CHAI

"This should be the new standard for global health." CHAI CEO Dr. Neil Buddy Shah on the first generic lenacapavir for HIV prevention, tentatively approved by the US FDA just 16 months after the originator. clintonhealthaccess.org/news… @UNITAID, @WitsRHI, @drreddys, @GileadSciences

“We can actually begin to bring an end to the HIV epidemic.” CHAI’s Carolyn Amole on scaling generic lenacapavir to the 20 million people who need PrEP, in @AP's coverage of the news: ow.ly/ji2N51039eY

The first generic lenacapavir has US FDA tentative approval, just 16 months after the originator’s approval. A twice-yearly injection at US$40pppy in 120 LMICs. First supplies expected in countries by year-end. ow.ly/Zu5S51038Rq @UNITAID @WitsRHI @drreddys @GileadSciences

From our 2025 Annual Report: • US$40 pppy for generic lenacapavir • ~58M Ethiopians with reliable oxygen access • 666K+ girls vaccinated against HPV in Liberia • US$1 sickle cell diagnostic test + aid cuts, AI, and more Download: ow.ly/6nPW51023Sj

Our 2025 Annual Report is out now. Read how CHAI worked with governments to protect essential services in one of the hardest years global health has faced. ow.ly/9jm651023Lw

22,000+ Village Health Workers in #Zimbabwe now get paid on time through a system the government owns. Payment rejections: 25% to <5%. How a national VHW Master List made it happen 👇 ow.ly/7vje5100fZT Led by @MoHCCZim with @GlobalFund Project BIRCH, @Frontline1st and CHAI.

Count lives saved, and count the health systems that keep saving them. CHAI CEO @NeilBuddyShah in @nytimes on why “effective” philanthropy has to include health systems: ow.ly/AIO45100Z9F

TB prevention options growing from what is available today to new TPT regimens, long-acting injectables, and novel vaccines. Our new toolkit compares them all: ow.ly/AP7z50ZYuoa #TBPrevention @GlobalFund @WHO @gatesfoundation @gavi

Could AI allow health systems in LMICs leapfrog legacy systems in wealthier countries? CEO @NeilBuddyShah on how ministries of health can flip the script: ow.ly/9gIH50ZZpJu

AI can put expert-level ultrasound reads in the hands of frontline health workers. CEO @NeilBuddyShah on what it will take to price, regulate, and scale tools like this: ow.ly/afcX50ZZpyM

Several new TB prevention tools are in trials. But children aged 5-14 in the general population aren’t covered by any of them. Our new toolkit lays out who the pipeline could reach, and where gaps remain. ow.ly/JtWJ50ZYuoU @GlobalFund @WHO @gatesfoundation @gavi

"There are large amounts of capital coming in to solve some of the most important problems in the world." Our CEO @NeilBuddyShah in @nytimes on how new AI-era philanthropy could reshape global health, and why health systems have to be part of the answer: ow.ly/O6gw50ZZs3l

What’s on the horizon for TB prevention? Our new toolkit puts today’s options and the pipeline of new pharmaceutical prevention options side by side. ow.ly/nvvG50ZYu8k #TBPrevention @GlobalFund @WHO @gatesfoundation @gavi

CHAI has helped negotiate more than 140 deals that lowered prices of life-saving medicines and diagnostics. Why do they work? CEO @NeilBuddyShah explains on @MedAccessUK's new podcast: ow.ly/iUzR50ZZ5Zu

It’s #ILPPW: 1 in 3 children worldwide have blood lead levels above @WHO threshold, yet testing is out of reach in many countries. Join CHAI & @RenPhilanthropy on Oct 29, 10am EDT to discuss low-cost testing & an open call for innovators. @VitalStrat @UW ow.ly/hxfX50ZYZ0h

"Before I could not thread the needle in my sewing machine, but now I can do it very well." Maryam Yakub, a tailor for more than 13 years, got free reading glasses through Nigeria's Jigi Bola 2.0, which reached 1.3 million people in year one. #WorldSightDay

Join us Oct 8 for a virtual Innovator Showcase on LLM-enabled clinical decision support, hosted by the AI Commons for Global Health, which we co-launched with Endless Health (@rubayatkhan) and @AgencyFund. 8am ET | 3pm EAT | 5:30pm IST Register: ow.ly/4nIP50ZUFji

38% -> nearly 100% across 50+ districts. In Uganda, almost every child who needs oxygen now gets it. The fix started with a simple idea: swap empty cylinders for full ones at delivery. #WorldOxygenDay #InvestInOxygen @MinofHealthUG | @gatesfoundation

A year ago, we announced a deal to bring lenacapavir, a twice-yearly HIV prevention shot, to 120 LMICs for US$40. Now the focus is delivery. CHAI CEO Buddy Shah joined @AlterIgoe on @devex Theory of Change at #UNGA81. ow.ly/34K650ZTF94 @drreddys | @UNITAID | @WitsRHI

This week Papua New Guinea launched HPV vaccinations nationally, reaching an estimated 60,000 girls aged 9–14 in its first phase—protecting women against cervical cancer, the country's leading cause of cancer deaths. Proud to support the Government of PNG, @gavi @WHO, @UNICEF