Disease Models & Mechanisms - discovery for human health. A @Co_Biologists Open Access journal that publishes human disease research.
Cambridge, UK
Joined September 2009
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*** Call for papers deadline extended ***
Submit your latest #Paediatric #GeneticDiseases paper to be included in our next special issue.
The deadline has been extended to 7 December 2026. Find out more today 👇️
tinyurl.com/3b8zscaz
ALT Call for papers - Special Issue - Paediatric Genetic Diseases: Models, Mechanisms and Therapies. Edited by James Amatruda, Ross Cagan and Elaine Mardis. Extended deadline: 7 December 2026.
A bioengineered platform reveals progressive impairment of skeletal muscles by metabolic dysfunction-associated steatotic liver disease-derived factors.
Check out the Research Article by Armando Cortés-Reséndiz & co: doi.org/10.1242/dmm.052820
ALT Schematic representation of construct fabrication and experimental timeline of the model.
Check out the #FirstPerson interview with Armando, a PhD student in the lab of Javier Ramón-Azcón at Institute for Bioengineering of Catalonia (IBEC), developing human in vitro models to investigate complex disease mechanisms and organ–organ interactions. doi.org/10.1242/dmm.053137
ALT Armando Cortés-Reséndiz
We are delighted to support the Milner Therapeutics Institute seminar series. Don't miss the next seminar on 18 November, with a focus on #neurodegeneration. In the meantime, read DMM's neurodegeneration subject collection: journals.biologists.com/dmm/…
Milner Seminar: Focus on neurodegeneration 🧠
🗓️ 18 November
⏰ 4-5pm
📍 Jeffrey Cheah Biomedical Centre
Speakers:
Maura Malpetti, Department of Clinical Neurosciences and John Skidmore, @ALBORADA_DDI.
Special thanks to our sponsors @DMM_Journal!
🔗 ow.ly/VXhT50ZRmce
DMM Journal retweeted
Registration is now open to attend our 2027 Journal meeting on #metabolism, organised by Sally Dunwoodie, Irene Miguel-Aliaga @FlyGutLab, Satdarshan [Paul] Singh Monga & Hans-Georg Sprenger
Apply to attend at tinyurl.com/k56s3rk4
#BiologistsMetabolism
ALT Metabolism: From Cellular Mechanisms to Development and Disease 21 – 23 June 2027, St Mary’s Marylebone, London, UK
We are pleased to be a @reviewcommons.org affiliate journal. Our Academic Editors are happy to consider transfers from Review Commons.
Find out more about the platform and why authors chose it: embo.org/features/why-i-chos…
For your #WeekendRead - Tracey Murray Stewart and colleagues present an improved mouse model of #SnyderRobinsonSyndrome, providing a robust platform for therapy testing.
Read and share the article for free doi.org/10.1242/dmm.052953
ALT Effects of the SmsG56S allele on regional protein expression in the brain
Today is #BreastCancerAwareness #WearItPink day. In our interview with Funmi Olopade, she talks about her serendipitous research path, improving care for breast cancer patients and the heroism of women in genetics. doi.org/10.1242/dmm.049198
Claes Fryklund & co use longitudinal metabolic phenotyping to identify a fixed-dose streptozotocin protocol that produces a stable type 2 diabetes-like phenotype in high-fat-diet-fed mice.
Check out this article for free in DMM: doi.org/10.1242/dmm.053071
ALT Mathematical modelling of STZ intervention in mice. Schematic representation of the mathematical model structure.
‘Why is publishing so expensive?’
This year’s theme for #OAweek is #TheCostOfKnowledge - an opportunity to revisit the Editorial where DMM, a fully Open Access journal, is transparent about its publishing finances: journals.biologists.com/dmm/…
We're still celebrating #OAweek: Our subject collections of #openaccess reviews and research articles make it easy to browse your favourite topics: journals.biologists.com/dmm/…
Ignacio Simó and colleagues find polyQ-expanded ataxin-3 is associated with mitochondrial alterations in #MachadoJosephDisease
Read the Research Article for free: doi.org/10.1242/dmm.052757
ALT Primary cortical neuron cultures from CMVMJD135 and WT embryos and analysis of mitochondrial and metabolic markers.
To find out more about this research, check out the #FirstPerson interview with Ignacio, a postdoc in the lab of @AngelaSLaird at Macquarie University, investigating mitochondrial dysfunction, cellular metabolism and m6A RNA regulation doi.org/10.1242/dmm.053121
Celebrate #OAweek 2026 with DMM. Learn more about DMM's Open Access policies journals.biologists.com/dmm/…
Female-specific alterations in insulin dynamics are associated with glucose tolerance in a Glut1DS mouse model
Check out the article by Tamio Furuse & co: doi.org/10.1242/dmm.052836
ALT Glucose-related features measured in clinical blood chemistry test.
Thank you to organisers James Amatruda, Pratiti (Mimi) Bandopadhayay, Ana Banito and Elaine Mardis and everyone who joined us last week for our meeting on Innovative Preclinical Models for Pediatric Cancer Research
#DMM2026cancer
For your #WeekendRead this #BreastCancerAwarenessMonth - Functional exploration of copy number alterations in a Drosophila model of triple-negative breast cancer.
Read the article by Diaz et al: doi.org/10.1242/dmm.050191
Eduardo Vieira Neto and colleagues characterise the #cardiomyopathy developed by a mouse model carrying a mutation in the β-subunit of mitochondrial trifunctional protein
Read and share for free: doi.org/10.1242/dmm.052921
ALT Myocardial interstitial fibrosis in a homozygous βTFP-deficient mouse with the highest collagen fraction.
DMM Editors - Jim Amatruda, Steve Clapcote, Elaine Mardis, Liz Patton and Karen Liu - at the DMM meeting earlier this week, exploring Nationwide Children’s Hospital @nationwidekids in Columbus, Ohio. nationwidechildrens.org/
Thank you to everyone who made the DMM meeting on Innovative Preclinical Models for Pediatric Cancer Research a success! See our wonderful venue all set for presentations below - Nationwide Children’s Hospital Conference Center - and Columbus looking beautiful in the sun ☀️
ALT Columbus, Ohio in the sun
ALT A conference room, set up with a slideshow and empty chairs on the stage for a panel talk
ALT A room full of delegates sat in rows listening to a talk at the conference
DMM Journal retweeted
The Company of Biologists is a not-for-profit publisher that exists to support biologists and inspire biology. This video tells you more about our aims and activities.
youtu.be/lVH6zgfl-zM
