50 years after the publication of The Selfish Gene, it's time for books that capture the complexity of life to take centre stage go.nature.com/4dXkdlX

Nature research paper: Persistent neuronal stress signalling underlies Angelman syndrome phenotypes go.nature.com/48cSSIY

In nematodes, a metabolite induced by the cold links low temperatures to a body-wide signal that promotes longevity go.nature.com/3UIGTjk

Nature research paper: Structural basis for protocadherin-1 recognition by New World hantaviruses go.nature.com/4ieepFS

A more than 40% risk reduction “would send many researchers over the Moon”. This personalised mRNA vaccine reduced the risk of skin cancer returning or the recipient dying by 42% go.nature.com/4zIVp9E

The speed at which regions of the brain mature during early adolescence can forecast the emergence of mental-health conditions up to four years before symptoms develop go.nature.com/4ik40Zn

A powerful gene-editing technique has been used to edit DNA directly in a person’s body — the first known instance of such a treatment. go.nature.com/4iC2gMn

Scientists have mapped one of the most mysterious parts of the human brain in unprecedented detail go.nature.com/4slBv1T

“We are finally starting to put a face to the Denisovan” go.nature.com/4jCV43G

Evidence grows for ‘circadian depression’ go.nature.com/4yHVJ7R

Money from the world’s increasingly prosperous technology entrepreneurs has been flooding into biomedical research. Is it changing how science is done? go.nature.com/3WmNwIz

Nature research paper: GRP75-dependent SIMPA mediates inter-organellar quality control go.nature.com/4zQqXux

Latest from the Nature Pod 🔊 The team discuss how precisely measuring a positron could shed light on one of physics’ greatest mysteries — plus, the latest on an ambitious mission to a Martian moon go.nature.com/4i9TTX2

This drug has been approved for the treatment of narcolepsy, but could also treat conditions across the health spectrum - could it be the next blockbuster? go.nature.com/3UiRx06

Can a human survive in a whale’s belly? Can a glowing jellyfish work as a torch? Nature speaks to researchers about the science behind the new film Whalefall. go.nature.com/3UGvdO8

You Can See Everything chronicles the final weeks before disgraced entrepreneur Elizabeth Holmes went to prison in 2023 go.nature.com/4eP3tgZ

Nature research paper: Programmable design of functional proteins from natural language go.nature.com/47xbVh8

Scientists tracked the changing sleep patterns of Indigenous people in Argentina who gained access to mains electricity — and smart phones go.nature.com/4yCFTv8

A cancer patient in France has become the first human known to contract the Shamonda virus go.nature.com/4dWWzGe

The use of AI tools in medicine is increasing. What types of technology might be on the horizon and how can such health-advice tools be tested? go.nature.com/4dTvPq3