David Perlmutter, MD (@DavidPerlmutter) header
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Board-Certified Neurologist | Harvard CME Faculty | 7x NYT bestselling author Empowering you to take control of your brain health.

Naples, Florida, USA
Joined July 2009
Photo by David Perlmutter, MD (@DavidPerlmutter)Photo by David Perlmutter, MD (@DavidPerlmutter)Photo by David Perlmutter, MD (@DavidPerlmutter)Photo by David Perlmutter, MD (@DavidPerlmutter)Photo by David Perlmutter, MD (@DavidPerlmutter)Photo by David Perlmutter, MD (@DavidPerlmutter)Photo by David Perlmutter, MD (@DavidPerlmutter)Photo by David Perlmutter, MD (@DavidPerlmutter)Photo by David Perlmutter, MD (@DavidPerlmutter)
Today, Brain Defenders is officially available. After more than 40 years of research, clinical experience, and asking different questions about Alzheimer’s disease, this book feels like the culmination of everything I’ve learned about protecting cognitive health for the long term. I truly believe it’s some of the most important work I’ve done. Your brain’s future is not predetermined. You have more agency over your cognitive health than you may have been led to believe. I hope you’ll join me for this next chapter in protecting your brain. Order your copy: braindefenders.com/
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Brain aging begins earlier than you think. Your diet, sleep, movement, and metabolic health can influence inflammation and how well your brain functions over time. Are your daily habits protecting your brain? Take my free assessment: drperlmutter.com/the-brain-d…
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Halloween is this Saturday, and candy is everywhere. While an occasional treat is one thing, consistently high sugar intake can contribute to insulin resistance, a major concern for long term brain health. A reminder that what you eat today can influence your brain health tomorrow.
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A simple technique may help reduce anxiety in just minutes. On this week's episode of The Empowering Neurologist, I'm joined by @nickortner, bestselling author and CEO of The Tapping Solution, to explore the science behind tapping and its potential benefits for stress, anxiety, and cognitive function. Tune into the full episode here: youtu.be/JV-M0s8iv2g
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Millions of dollars have been spent chasing the wrong target in Alzheimer’s. For decades, beta-amyloid has dominated Alzheimer’s research. Yet even when drugs successfully remove amyloid from the brain, the cognitive decline that defines the disease continues. That should force us to ask a different question. What is driving the disease process in the first place? In my Brain Defenders Immersion Course, we go much deeper into the biology of Alzheimer’s, including the role of metabolism, inflammation, microglia, and the factors that may influence brain health long before memory begins to fail. Join me: drperlmutter.com/immersion-c…
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Your brain is not separate from your environment. Many scented candles and air fresheners release volatile organic compounds, or VOCs, into indoor air. Some VOC exposures are associated with symptoms that include headache, dizziness, and memory-related effects. A simple swap: simmer cinnamon sticks, orange slices, cloves, and rosemary. Better home fragrance. Less unnecessary chemical exposure.
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I’m honored to be presenting at Eudēmonia Summit in West Palm Beach, November 5- 8! Join me and leading voices in health and wellness for conversations on the future of wellbeing. Use code DPERLMUTTER for 10% off your badge: eudemonia.net/dperlmutter
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Your brain cannot afford bad sleep. Chronic sleep disruption can affect far more than your energy levels, including inflammation, metabolic health, and long-term brain health. I discussed this and more wih @thegarybrecka. Watch here: youtu.be/JJqBbx6c9qM
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Your lab results can offer important clues about what is happening metabolically long before changes in brain function become apparent. 3 markers I pay particular attention to: Fasting insulin: Ideally 2–5 µIU/mL. Above 10 may signal insulin resistance. Homocysteine: Above 15 µmol/L is elevated. Vitamin D: I generally look for 60–80 ng/mL.
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Your oral health is not limited to your mouth. It affects your entire system. Research is now exploring how bacteria linked to gum disease may contribute to neuroinflammation and Alzheimer’s disease. I discussed this with @askthedentist: youtu.be/k8jAXzYaUhk
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Brain health can feel overwhelming: sleep, exercise, nutrition, metabolic health. Where do you even begin? Start with the next choice in front of you. Take a walk after a meal. Prioritize sleep tonight. Choose food that supports stable blood sugar. Check your blood pressure. Build consistency before complexity. Brain health is not built through one dramatic change. It is built through repeated daily decisions. For a practical roadmap, Brain Defenders offers steps to help you get started: braindefenders.com/
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David Perlmutter, MD retweeted
Consistently getting less than 6 hours of sleep has been associated with a 30% increased dementia risk.
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What happens when AI can predict something about your future that you’d rather not know? In my conversation with @TillyNorwoodX's creator, @Elinehq, we explored some unsettling possibilities. Watch here: youtu.be/wGLyO-vfn0Q
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Your age at menopause could predict your brain health years later. I recently spoke with @Preventionmag about new research examining the relationship between the timing of menopause and long-term cognitive health. The findings add to an important and evolving conversation about how hormonal changes during midlife may influence the female brain and why this period deserves far more attention when thinking about Alzheimer’s risk. Read the full article here: prevention.com/health/a74030…
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If you've ever felt busy, capable, and needed, yet somehow invisible, this conversation is for you. On this episode of The Empowering Neurologist, John R. Miles joins me to explore the difference between being useful and truly mattering. It's far more than an emotional question. Feeling unseen can influence your sleep, inflammation, and even how your brain perceives threat. youtu.be/IQtn4un-wFU?si=yDtO…
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Scented-candle season is here, and it’s worth thinking about what you’re putting into the air inside your home. Fragranced products can release a mixture of compounds into indoor air, especially in spaces with limited ventilation. If you love candles, consider using them less often or finding cleaner options, ventilating the room, and paying attention to the other scented products you use throughout the day.
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Your brain is responding every day to the environment you create for it. What you eat, how you sleep, how often you move, your stress level, and even the people you spend time with all matter. What is one change you have made that has noticeably improved how you feel?
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Feeling like you don't matter can take a toll on your brain health. On this week's episode of The Empowering Neurologist, I'm joined by John R. Miles, host of the Passion Struck podcast and author of The Mattering Effect, to explore the difference between being valued for what we accomplish and feeling valued for who we are. youtu.be/IQtn4un-wFU
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