@AlexPJMartin
 Lyon, France
Joined December 2015
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An exciting new collaboration between Lena Tveriakhina and Gustavo Scanavachi of the Blacklow and Kirchhausen labs. Unprecedented real time imaging of Notch signaling in living cells. @KirchhausenLab @LenaTveri @GuScanavachi Check out the preprint here - biorxiv.org/content/10.1101/…

Temporal Dynamics and Stoichiometry in Notch Signaling - from Notch Synaptic Complex Formation to...

Mammalian Notch signaling occurs when binding of Delta or Jagged to Notch stimulates proteolytic release of the Notch intracellular domain (NICD), which enters the nucleus to regulate target gene...

biorxiv.org
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Building a time-resolved subcellular map, @BlacklowLab tracks the path of the intracellular domain of #Notch during its journey to the cell nucleus and find that the domain isn’t released from the plasma membrane as was previously thought. #CellBiology scim.ag/3Ap
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