@AngTopher

PhD candidate at the @JodyPeters20 Lab. Fascinated by ISFs and ISVs.

 Brisbane, Queensland
Joined March 2021
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🚨 We found some cool viruses in Singapore!! 🚨 Over 18 months, we screened 17,070 🦟mosquitoes across 17 locations in Singapore, uncovering 🦠viruses that could shape future biocontrol strategies against dengue and other arboviruses! 🔗: doi.org/10.1099/jgv.0.002105 🧵👇 (1/)
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Can Hantavirus cruise into the next pandemic? - PMC ⁦@PlaqueAssay⁩ and @alberilla spitting facts!! pmc.ncbi.nlm.nih.gov/article…

Can Hantavirus cruise into the next pandemic?

Despite concerns arising from a recent ship-associated outbreak on the M/V Hondius cruise, current evidence suggests that Andes virus (ANDV) poses a low pandemic risk. Nevertheless, viral evolution,...

pmc.ncbi.nlm.nih.gov
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Zika virus produces two isoforms of the NS2A protein that play mutually exclusive roles in viral replication and virion assembly | PLOS Pathogens journals.plos.org/plospathog…

Zika virus produces two isoforms of the NS2A protein that play mutually exclusive roles in viral...

Author summary The Orthoflavivirus NS2A protein is a small, hydrophobic, integral membrane protein implicated in both viral RNA replication and virion assembly. However, how NS2A participates in...

journals.plos.org
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SCMB’s @JodyPeters20, @HenryDmal & @JessHarrison03 developed the ISVac™ platform using non‑infectious virus particles. It's now moving toward human trials with Proboxis Biotechnology, a start up with support from Uniquest & $1.5M via Biointelect Venturer. tinyurl.com/9bumpb7u
Dr Jessica Harrison, Dr Henry de Malmanche, and A/Prof Jody Peters

ALT Dr Jessica Harrison, Dr Henry de Malmanche, and A/Prof Jody Peters

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Longitudinal dynamics and lineage cross-reactivity of the human antibody response to West Nile virus | mBio journals.asm.org/doi/10.1128…

Longitudinal dynamics and lineage cross-reactivity of the human antibody response to West Nile...

West Nile virus (WNV) is a growing global health threat spread by mosquitoes that can cause severe disease, yet there are currently no approved vaccines or treatments available. We followed 55 WNV...

journals.asm.org
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Evolutionary Dynamics-Aware De Novo Design of a Thermostable NS1-Derived Diagnostic Protein for Yellow Fever Virus | ACS Omega | ACS Publications pubs.acs.org/acsodf/article/…

Evolutionary Dynamics-Aware De Novo Design of a Thermostable NS1-Derived Diagnostic Protein for...

Abstract. Serological diagnosis of neglected arboviruses remains hindered by extensive intra-genus cross-reactivity, compromising both assay specificity an

pubs.acs.org
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Dr Masaru Nobu gave an outstanding & thought provoking talk at Monday afternoon's 2026 Skerman lecture. He discussed the origins of life and life's adaptation to Earth's changing landscape. Afterward, fabulous discussion was had over afternoon tea.
Prof Phil Hugenholtz, Dr Masaru Nobu, and Prof James De Voss

ALT Prof Phil Hugenholtz, Dr Masaru Nobu, and Prof James De Voss

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Fast remote nucleotide sequence alignment with Riboseek | bioRxiv biorxiv.org/content/10.64898…

Fast remote nucleotide sequence alignment with Riboseek

Structure prediction has reached RNA, where generating deep alignments is now the bottleneck. We developed Riboseek, a search and alignment tool for RNA and DNA that represents sequences as overlap...

biorxiv.org
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Comparative analysis of flavivirus sfRNA dynamics and secondary structure | Journal of Virology journals.asm.org/doi/10.1128…

Comparative analysis of flavivirus sfRNA dynamics and secondary structure | Journal of Virology

Flaviviruses are highly prevalent human pathogens. The flavivirus genome contains RNA structural elements (RSEs), including those encoded in the 3′-UTR, that are necessary for viral replication....

journals.asm.org
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First paper with the lab's affiliation!! ✨✨ summarising some of the cool concepts that the Antigen Evolution & Design Lab will be working on! Together with amazing collaborators @Mahan_Ghafari and Joe Grove @CVRinfo annualreviews.org/content/jo… 🧵🧵

Studying the Deep Evolution of Viruses in the Era of Artificial Intelligence Structure Prediction

High mutation rates erode viral sequence similarity, obscuring deep evolutionary history. While protein structure is far more conserved than sequence, its use in evolutionary studies has historically...

annualreviews.org
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Genetic diversity of the Chikungunya virus E2 gene may have implications for the design of vaccines and therapeutic antibodies | Virus Genes | Springer Nature Link link.springer.com/article/10…
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Long-term antibody dynamics challenge the paradigm of lifelong homotypic immunity to dengue virus | PNAS Some important insights that could affect future vaccine and vector control strategies pnas.org/doi/10.1073/pnas.26…

Long-term antibody dynamics challenge the paradigm of lifelong homotypic immunity to dengue virus |...

Immunity following infection with the four dengue virus serotypes (DENV1-4) remains difficult to define. Reports of individuals being reinfected wi...

pnas.org
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The RNA promoter for pathogenic orthoflaviviruses replication is universal and serves as target for viral inhibition | PLOS Pathogens journals.plos.org/plospathog…

The RNA promoter for pathogenic orthoflaviviruses replication is universal and serves as target for...

Author summary Orthoflaviviruses are important human pathogens that cause recurrent outbreaks worldwide. These viruses infect both vertebrate and invertebrate hosts, including dengue, Zika, West...

journals.plos.org
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Small RNA genomics of Aedes aegypti mosquitoes discovers infectious viruses that trigger an RNA interference response | Nature Communications nature.com/articles/s41467-0…

Small RNA genomics of Aedes aegypti mosquitoes discovers infectious viruses that trigger an RNA...

Nature Communications - This study is a small RNA genomics survey from global Aedes aegypti mosquito samples, and detected replicating viruses. This study then isolated several mosquito viruses...

nature.com
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Christopher Ang retweeted
Eric Topol
@EricTopolApr 21
Predicting RNA 3D structure is a grand challenge of biology. 2 new approaches published today to get at it sciencedirect.com/science/ar… @MolecularCell nature.com/articles/s42256-0… @NatMachIntell
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Frontiers | Cloning, expression and characterisation of antigen-specific recombinant bat immunoglobulin from the black flying fox (Pteropus alecto) frontiersin.org/journals/imm…

Frontiers | Cloning, expression and characterisation of antigen-specific recombinant bat immunogl...

Bats are natural reservoir of viruses that cause severe disease in livestock and humans. Recent high-profile spillover events have directed significant atten...

frontiersin.org
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m6A epigenetic modification of viral RNA is critical for the transmission cycle of mosquito-borne flaviviruses | PNAS pnas.org/doi/10.1073/pnas.25…

m6A epigenetic modification of viral RNA is critical for the transmission cycle of mosquito-borne...

Arboviruses maintain alternative transmission routes between arthropods and vertebrates through precise dual-host adaptation of their viral genome....

pnas.org
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Dengue virus harnesses mosquito Syntenin to load and secrete viral RNA into salivary exosomes | PNAS pnas.org/doi/10.1073/pnas.25…

Dengue virus harnesses mosquito Syntenin to load and secrete viral RNA into salivary exosomes | PNAS

Viruses exploit extracellular vesicles (EVs) to transfer infection-enhancing viral RNAs. However, mechanisms underlying viral RNA loading remain el...

pnas.org
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Been so busy that I almost forgot how beautiful and tranquil the UQ lakes are. Not a cloud in the sky either!
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The Jody Peters Lab @JodyPeters20 at @UQ_SCMB finally has a website 🎉 After more than a decade studying arboviruses and insect-specific viruses, we now have a place to share what we do and make it easier to connect with us. peterslab-uq.github.io/Lab-W… Thread 👇

Peters Molecular Arbovirology Laboratory | The University of Queensland

The Peters Molecular Arbovirology Laboratory at The University of Queensland researches mosquito-borne viruses, developing next-generation vaccines, diagnostics and monoclonal antibody reagents.

petersvirologylab.com
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Over the years, we have also generated TONS of antibodies. MozzyMabs™ is our antibody collection that we are making available to the research community. If you are looking for antibodies and do not see what you need, please get in touch! We can probably work something out.
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If you are interested in arboviruses, vaccines, antibodies, or collaboration, check out our website to learn more about what we do: peterslab-uq.github.io/Lab-W… We are always happy to chat 👋

Peters Molecular Arbovirology Laboratory | The University of Queensland

The Peters Molecular Arbovirology Laboratory at The University of Queensland researches mosquito-borne viruses, developing next-generation vaccines, diagnostics and monoclonal antibody reagents.

petersvirologylab.com
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