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Just one amino acid prevents the small ruminant morbillivirus #PPRV from infecting human cells. Predicting viral zoonoses without gain-of-function tests.
jvi.asm.org/content/early/20…
ALT Overlay image of H proteins from PPRV (red), MeV (green), CDV (yellow) and RPV (blue). Residue R191 determines receptor specificity.
How do you track population immunity to COVID when national surveillance has ceased? A random selection of 1000 serum samples from the bio-repository of a major health board reveals valuable insights into current levels of COVID immunity.
papers.ssrn.com/sol3/papers.…
Repeated vaccination with mRNA-based vaccines led to a marked increase in class-switching to IgG4. As mRNA boosters have been restricted largely to the elderly, there is now a complex immunological landscape in which there is an age-related increase in SARS-CoV-2-specific IgG4.
Veterinary Virology retweeted
Additionally, research from @CVRPreparedness & colleagues tested blood from vaccinated people to measure antibody neutralisation of emerging variants.
Data show current boosters provide cross-protection against BA.2.86.
doi.org/10.1016/S0140-6736(2…
Veterinary Virology retweeted
📣 Delighted to share latest work by the @CVRinfo #Preparedness group, published in @TheLancet. 📣
Omicron BA.2.86 cross-neutralising activity in community sera from the UK
1/3
thelancet.com/journals/lance…
Risks for zoonotic spillover of Rift Valley fever virus (RVFV) in Tanzania. Strong positive association between the reported history of raw milk consumption and human RVFV seropositivity...dx.plos.org/10.1371/journal.…
Veterinary Virology retweeted
Having a great time working the @UofGlasgow labs! Great way to revise some key content and get hands on experience carrying out PCR, DNA sequencing and gel electrophoresis. @gsc1 @BellahoustonAc #STEM #DYW
Veterinary Virology retweeted
Today a group of S5 Higher Biologists enjoyed a PCR workshop ran by the @gsc1. Pupils were treated to gel electrophoresis, PCR, some virus diagnostics and discussed DNA technology with a group of scientists 👩🔬 👨🔬 @HillheadHS
Veterinary Virology retweeted
Thank so much @UofGlasgow and @gsc1 for a fantastic day at the PCR masterclass! Everyone from @KirkintillochHS had a great time and all of the staff were so helpful. The practical was great and a great intro to uni life #stem #biology #pcr
Day 3 of the @gsc1 and @CVRinfo PCR workshop at @UofGlasgow . Learning about DNA structure and diagnosing viral diseases.
Veterinary Virology retweeted
Out now: SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway. By Brian Willett, Emma Thomson & colleagues. @emcat1 @CVRbioinfo #omicron
Read it here: rdcu.be/cReRB
nature.com/articles/s41564-0…
New research reveals how Omicron variant escapes immune response hdruk.ac.uk/?p=526459
Great to see our study on the Omicron variant of SARS-CoV-2 finally published! A big thank you to all our collaborators 👏
rdcu.be/cRahG
@GroveLab @CVRinfo
The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism medrxiv.org/content/10.1101/…
Veterinary Virology retweeted
This paper concludes with this key sentence:
" Moreover, our work demonstrates that SARS-CoV-2 exhibits high antigenic and functional plasticity; further fundamental shifts in transmission and disease should be anticipated"
i.e. expect Covid to keep adapting.
📖NEW | Omicron pre-print🦠
Latest work by @cvrinfo reveals fundamental changes in the #Omicron variant. The study, led by @emcat1, uses laboratory experiments and real world infection data, and has three major findings👇
gla.ac.uk/researchinstitutes…
Veterinary Virology retweeted
Adding to yesterday's good day for T-cells against Omicron! :D @SetteLab @Alba_Grifoni @MarionKoopmans @Corine_GvK @bart_haagmans medrxiv.org/content/10.1101/…
Veterinary Virology retweeted
While SARS-CoV 2 is evident in white-tailed deer 🦌, the virus hasn’t mutated.
More info is key to understand impacts of the virus’ introduction to wildlife on ecosystems. We call on countries to: Encourage, Inform, Monitor, Share, Report
LEARN MORE 👉oie.int/en/oie-statement-on-…
Veterinary Virology retweeted
📖 READ | From hippos to hamsters: how #Covid is affecting creatures great and small🦠
Take a read as @margaret_hosie discusses #coronaviruses, how they mutate and jump between species in the @guardian!
theguardian.com/world/2021/d…
High anti-FeLV SU antibody levels correlate with a regressive infection, complementing existing diagnostic tests.
mdpi.com/1024798
ALT Graph depicting correlation between SU antibody levels and outcome of FeLV infection