aurelius omlin retweeted
Dear Colleagues at #ESMO25
Our Faculty🚨 @AOmlin and @Silke_Gillessen who are chairs of our partners at @APCCC_Lugano 🇨🇭Discuss trials presented here that will be hot topics in Lugano
Ping
@neerajaiims @tompowles1 @Ecastromarcos @BourlonMaite @cdanicas @nataliagandur
Dear #ESMO25 Big News from #APCCC26 🚨APCCC is opening a Call for Abstracts! 👉 apccc.org
Here are @Silke_Gillessen & @AOmlin to tell you why the discussions here in Berlin will be so relevant for APCCC in Lugano 🇨🇭
@APCCC_Lugano Creating new opportunities for younger investigators & the next generation of leaders in advanced #ProstateCancer
@fabioturco92
@Prof_IanD
@drjefstathiou
@Prof_Nick_James
@ChrisSweens1
@BertrandTOMBAL
@ZilliThomas
@neerajaiims
@bjartell
@PBlanchardMD
@BourlonMaite
@Albert0Briganti
@cdanicas
@Ecastromarcos
@mdesantis234
@nachoduranm
@drlouiseemmett
@stefanofanti4
@fontev1
@Nicola_Fossati
@marty_gleave
@ProfKHerrmann
@DrMHofman
@BarbaraJereczek
@ravikanesvaran
@FacsRaja
@LoebStacy
@quimmateo
@DrRanaMcKay
@amerseburger
@CaPsurvivorship
@declangmurphy
@DrPaulNguyen
@WilliamOhMD
@piet_ost
@DrSpratticus
@cnsternberg
@DrYukselUrun
@DrChoueiri
@tompowles1
@brian_rini
Ping
@nataliagandur
aurelius omlin retweeted
Optimized use of immunotherapy and targeted therapies in #mCRPC. Presentation by @AOmlin. #ESMO25 written coverage by @RKSayyid > bit.ly/47nUjnl @myESMO @neerajaiims
aurelius omlin retweeted
A warm invite to all, we wait for you at #APCCC26
⭐ Full details & submission apccc.org
@Silke_Gillessen & @AOmlin
@OncoAlert 🚨
@fabioturco92 @Prof_IanD @drjefstathiou @Prof_Nick_James @ChrisSweens1 @BertrandTOMBAL @ZilliThomas @neerajaiims @bjartell @PBlanchardMD @BourlonMaite @Albert0Briganti @cdanicas @Ecastromarcos @mdesantis234 @nachoduranm @drlouiseemmett @stefanofanti4 @fontev1 @Nicola_Fossati @marty_gleave @ProfKHerrmann @DrMHofman @BarbaraJereczek @ravikanesvaran @FacsRaja @LoebStacy @quimmateo @DrRanaMcKay @amerseburger @CaPsurvivorship @declangmurphy @DrPaulNguyen @WilliamOhMD @piet_ost @DrSpratticus @cnsternberg @DrYukselUrun @DrChoueiri @tompowles1 @brian_rini
Dear Colleagues at #ESMO25
An honor to present our faculty🚨 @Silke_Gillessen and @AOmlin straight from Berlin who discuss about:
The Radioligand Therapy Session on #ProstateCancer
VERY hot Topics and some that will spark up conversation in Lugano🇨🇭 for #APCCC26
@APCCC_Lugano
@montypal @crisbergerot @DrDanielHeng @apolo_andrea @DrChoueiri @PGrivasMDPhD @TiansterZhang @HHammersMD @ravikanesvaran @neerajaiims @amerseburger @sonpavde @drenriquegrande @scserendipity1 @Silke_Gillessen
@EfstathiouEleni @tompowles1 @BraunMDPhD @nataliagandur @cdanicas @bavilima
@yekeduz_emre @DrYukselUrun @TylerSbrt @mgmglobal @LoebStacy @piet_ost @_ShankarSiva @seanmmcbride
aurelius omlin retweeted
🧬 Cribriform architecture changes the story in localized prostate cancer.
🔥 ProtecT 15-year biopsy re-review shows who really needs treatment vs surveillance.
🎯 n = 712 with available slides (13 % cribriform+)
💊 Arms:
▫️ Active monitoring
▫️ Radical prostatectomy
▫️ Radiotherapy + neoadjuvant ADT
📊 Key Results
• Cribriform + → ↑ metastasis risk (HR 3.61, 95 % CI 1.60-8.11)
• RT + ADT → lowest metastasis (HR 0.35 vs active monitoring)
• Surgery → HR 0.52 vs active monitoring (NS)
• 15-yr metastasis (cribriform +): AM 25 % | Surg 26 % | RT + ADT 8 %
• Cribriform –: 7 % | 4 % | 3 %
✅ Takeaway:
Cribriform + = treat aggressively (RT + ADT best long-term control)
Cribriform – = active surveillance still safe for most patients.
📖 Sushentsev et al. JAMA Oncology 2025. 🔗 doi.org/10.1001/jamaoncol.20…
#OncoTwitter #MedTwitter #ProstateCancer #UroOnc
@OncoAlert @myesmo @esmo_open @ASCO @JAMAOnc
aurelius omlin retweeted
Great talk by @TylerSbrt about the complementarity of MRI and PSMA PET, and the future of imaging is quantitative #APCCCDiagnostics25 @OncoAlert
aurelius omlin retweeted
🌟 LIVE from #APCCC25! #APCCCDiagnostics25
📢 The PSMA train has left the station… are you on it? 🚆
💡 @DrMHofman delivering brilliant insights on the paradigm shift in prostate cancer imaging!
@APCCC_Lugano @OncoAlert
🔍 CT/Bone Scan vs. Next-Gen PSMA PET—how do we adapt clinical decisions?
📊 PSMA PET is redefining detection & treatment planning, leading to earlier and more precise interventions!
🔥 Key Takeaways:
✅ PSMA PET significantly reduces false positives compared to CT/BS (7% vs. 23%)
✅ Better disease delineation → better management decisions
✅ FDG PET/CT helps detect PSMA-negative lesions, improving accuracy
💬 What’s next in imaging? How do we optimize multi-modality approaches for prostate cancer?
@ProfKHerrmann @stefanofanti4 @Silke_Gillessen @AOmlin @Albert0Briganti @Ecastromarcos @drlouiseemmett @DrAGafita @karolien_goffin @ProfHadaschik @DrMHofman @Prof_Nick_James @piet_ost @gpalapa2 @MoniqueRoobol @TylerSbrt @DrSpratticus @Tilki_De @BertrandTOMBAL @Nina18205 @UrsulaVogl @ResearchWyatt – at Ciudad Autónoma de Buenos Aires, Argentina
aurelius omlin retweeted
When to assess biology with a re-biopsy? Presentation by @mishabeltran @DanaFarber. #APCCCDiagnostics25 written coverage by @zklaassen_md @GACancerCenter > bit.ly/4kiSpKm #APCCC25 @APCCC_Lugano
aurelius omlin retweeted
🔥 A FANTASTIC Day 2 at #APCCCDiagnostics25 in Lugano!
🎙️ @Silke_Gillessen 🇨🇭 & @AOmlin 🇨🇭 share their insights on this inaugural edition, highlight key takeaways, unexpected surprises, and already set the stage for #APCCCDiagnostics27!
🚀 Looking ahead to the future of #ProstateCancer diagnostics!
@APCCC_Lugano @OncoAlert – at Ciudad Autónoma de Buenos Aires, Argentina
A GREAT DAY 2 of #APCCCDiagnostics25 from Lugano
@Silke_Gillessen 🇨🇭& @AOmlin 🇨🇭 Give us their take of this inaugural edition of this meeting, unexpected surprises and leave us already looking forward to #APCCCDiagnostics27
@APCCC_Lugano #ProstateCancer 🚨 @OncoAlert
Scientific Committee
@ProfKHerrmann 🇩🇪
@stefanofanti4 🇮🇹
@Silke_Gillessen 🇨🇭
@AOmlin 🇨🇭
Ambassadors
@LoebStacy 🇺🇸
@ZilliThomas 🇨🇭
@nataliagandur 🇦🇷
@bavilima 🇧🇷
@fabioturco92 🇨🇭
@weoncologists 🇺🇸
The #APCCCDiagnostics Panel
@bjartell
@Albert0Briganti
@Ecastromarcos
@drlouiseemmett
@DrAGafita
@karolien_goffin
@ProfHadaschik
@DrMHofman
@Prof_Nick_James
@piet_ost
@gpalapa2
@MoniqueRoobol
@TylerSbrt
@DrSpratticus
@Tilki_De
@BertrandTOMBAL
@Nina18205
@UrsulaVogl
@ResearchWyatt
aurelius omlin retweeted
The @APCCC_Lugano #APCCC24 Webinar on Management of patients with Advanced #ProstateCancer : Cases from #APCCC24
LINK TO ARTICLE👇👇👇👇👇👇👇👇
sciencedirect.com/science/ar…
ENTIRE WEBINAR HERE in this post
@Silke_Gillessen & @AOmlin
A great Pleasure to Present the first @APCCC_Lugano #APCCC24 Webinar on Management of patients with Advanced #ProstateCancer : Cases from #APCCC24
LINK TO ARTICLE👇👇👇👇👇👇👇👇
sciencedirect.com/science/ar…
ENTIRE WEBINAR HERE in this post
The 2024 Advanced Prostate Cancer Consensus Conference (APCCC) highlights significant advances in prostate cancer management while underscoring areas where high-quality evidence is still lacking.
A warm invite from
@Silke_Gillessen 🇨🇭 & @AOmlin 🇨🇭
@fabioturco92
@Prof_IanD
@drjefstathiou
Karim Fizazi
@Prof_Nick_James
Neal Shore
Eric Small
Matthew Smith
@ChrisSweens1
@BertrandTOMBAL
@ZilliThomas
@neerajaiims
Emmanuel S. Antonarakis
Ana Aparicio
Andrew J. Armstrong
Diogo Assed Bastos
Gerhardt Attard
Karol Axcrona
Mouna Ayadi
Himisha Beltran
@bjartell
@PBlanchardMD
@BourlonMaite
@Albert0Briganti
Muhammad Bulbul
Consuelo Buttigliero
Orazio Caffo
@cdanicas
@Ecastromarcos
Heather H. Cheng
Kim N. Chi
Caroline S. Clarke
Noel Clarke
Johann S. de Bono
@mdesantis234
@nachoduranm
@EfstathiouEleni
Onyeanunam N. Ekeke
Tamer I.H. El Nahas
@drlouiseemmett
@stefanofanti4
Omolara A. Fatiregun
Felix Y. Feng
Peter C.C. Fong
@fontev1
@Nicola_Fossati
Daniel J. George
@marty_gleave
Gwenaelle Gravis
Susan Halabi
Daniel Heinrich
@ProfKHerrmann
@DrMHofman
Thomas A. Hope
Lisa G. Horvath
Maha H.A. Hussain
@BarbaraJereczek
Robert J. Jones
Anthony M. Joshua
@ravikanesvaran
Daniel Keizman
@FacsRaja
Gero Kramer
@LoebStacy
Brandon A. Mahal
Fernando C. Maluf 75 76,
@quimmateo
David Matheson 78,
Mika P. Matikainen 79,
Ray McDermott 80,
@DrRanaMcKay
Niven Mehra 82,
@amerseburger
@CaPsurvivorship
Michael J. Morris 85,
Hind Mrabti 86,
Deborah Mukherji
@declangmurphy
Vedang Murthy
Shingai B.A. Mutambirwa
@DrPaulNguyen
William K. Oh
@piet_ost
Joe M. O’Sullivan
Anwar R. Padhani
Chris Parker
Darren M.C. Poon
Colin C. Pritchard
Danny M Rabah
Dana Rathkopf
Robert E. Reiter
Raphaele Renard-Penna
Charles J. Ryan
Fred Saad
Juan Pablo Sade
Shahneen Sandhu
Oliver A. Sartor
Edward Schaeffer
Howard I. Scher
Nima Sharifi
Iwona A. Skoneczna
Howard R. Soule
@DrSpratticus
Sandy Srinivas
@cnsternberg
Hiroyoshi Suzuki
Mary-Ellen Taplin
Camilla Thellenberg-Karlsson
Derya Tilki
Levent N. Türkeri
Hiroji Uemura
@DrYukselUrun
Claire L. Vale
Neha Vapiwala
Jochen Walz
Kosj Yamoah
Dingwei Ye
Evan Y. Yu
Almudena Zapatero
aurelius omlin retweeted
A great Pleasure to Present our paper on Management of patients with Advanced #ProstateCancer : A Report from #APCCC24
LINK TO ARTICLE👇👇👇👇👇👇👇👇
sciencedirect.com/science/ar…
The 2024 Advanced Prostate Cancer Consensus Conference (APCCC) highlights significant advances in prostate cancer management while underscoring areas where high-quality evidence is still lacking.
The conference gathered expert opinions on controversial clinical issues, particularly in advanced prostate cancer, offering guidance in cases where guidelines are unclear or conflicting.
The report emphasizes personalized treatment approaches, considering patient-specific factors and evolving clinical data, and stresses the importance of ongoing clinical trials to fill knowledge gaps. It provides a practical framework for physicians and patients to engage in shared decision-making, especially in complex cases of high-risk localized and locally advanced prostate cancer.
Our Thanks to all authors:
@Silke_Gillessen
@fabioturco92
@Prof_IanD
@drjefstathiou
Karim Fizazi
@Prof_Nick_James
Neal Shore
Eric Small
Matthew Smith
@ChrisSweens1
@BertrandTOMBAL
@ZilliThomas
@neerajaiims
Emmanuel S. Antonarakis
Ana Aparicio
Andrew J. Armstrong
Diogo Assed Bastos
Gerhardt Attard
Karol Axcrona
Mouna Ayadi
Himisha Beltran
@bjartell
@PBlanchardMD
@BourlonMaite
@Albert0Briganti
Muhammad Bulbul
Consuelo Buttigliero
Orazio Caffo
@cdanicas
@Ecastromarcos
Heather H. Cheng
Kim N. Chi
Caroline S. Clarke
Noel Clarke
Johann S. de Bono
@mdesantis234
@nachoduranm
@EfstathiouEleni
Onyeanunam N. Ekeke
Tamer I.H. El Nahas
@drlouiseemmett
@stefanofanti4
Omolara A. Fatiregun
Felix Y. Feng
Peter C.C. Fong
@fontev1
@Nicola_Fossati
Daniel J. George
@marty_gleave
Gwenaelle Gravis
Susan Halabi
Daniel Heinrich
@ProfKHerrmann
@DrMHofman
Thomas A. Hope
Lisa G. Horvath
Maha H.A. Hussain
@BarbaraJereczek
Robert J. Jones
Anthony M. Joshua
@ravikanesvaran
Daniel Keizman
@FacsRaja
Gero Kramer
@LoebStacy
Brandon A. Mahal
Fernando C. Maluf 75 76,
@quimmateo
David Matheson 78,
Mika P. Matikainen 79,
Ray McDermott 80,
@DrRanaMcKay
Niven Mehra 82,
@amerseburger
@CaPsurvivorship ,
Michael J. Morris 85,
Hind Mrabti 86,
Deborah Mukherji
@declangmurphy
Vedang Murthy
Shingai B.A. Mutambirwa
@DrPaulNguyen
William K. Oh
@piet_ost
Joe M. O’Sullivan
Anwar R. Padhani
Chris Parker
Darren M.C. Poon
Colin C. Pritchard
Danny M Rabah
Dana Rathkopf
Robert E. Reiter
Raphaele Renard-Penna
Charles J. Ryan
Fred Saad
Juan Pablo Sade
Shahneen Sandhu
Oliver A. Sartor
Edward Schaeffer
Howard I. Scher
Nima Sharifi
Iwona A. Skoneczna
Howard R. Soule
@DrSpratticus
Sandy Srinivas
@cnsternberg
Hiroyoshi Suzuki
Mary-Ellen Taplin
Camilla Thellenberg-Karlsson
Derya Tilki
Levent N. Türkeri
Hiroji Uemura
@DrYukselUrun
Claire L. Vale
Neha Vapiwala
Jochen Walz
Kosj Yamoah
Dingwei Ye
Evan Y. Yu
Almudena Zapatero
@AOmlin
aurelius omlin retweeted
🌍 Just in time for #EarthMonth, check out my new paper “Engaging in Clinical Research & Practice Approaches that Reduce Environmental Impact.” Thx to the team @EurUrolOncol for this opportunity- so many ways we can make a difference! 🌱
Full text link: sciencedirect.com/science/ar… – at Manhattan, NY
aurelius omlin retweeted
When Oligometastatix (aka me) and Pelvix (aka @VedangMurthy) share a 3h train ride home from #APCCC24 , new trials are born! Be ready for us #APCCC30! Thanks again @Silke_Gillessen and @AOmlin for having us.
aurelius omlin retweeted
Sad to be leaving #APCCC24 and beautiful Lugano, but what a fantastic meeting it has been. Plenty to think about, and some practice-changing information. Thank you @Silke_Gillessen @AOmlin @APCCC_Lugano for giving me the joy and privilege of being part of such a great community.
aurelius omlin retweeted
Agree, one of the best and most comprehensive talks I have ever heard about the topic- and in 10 minutes! Thanks @heatherhcheng !
#APCCC24 @APCCC_Lugano 👉Excellent talk by @heatherhcheng on who should undergo germ line testing?👉ongoing neoadjuvant trials in germline mutation+ #prostatecancer and take home message👇@OncoAlert @PCF_Science @Silke_Gillessen
aurelius omlin retweeted
💫🌟 #APCCC24 Day 3️⃣ Highlights 🌟💫
@APCCC_Lugano @OncoAlert
@Silke_Gillessen @AOmlin
1. 🧬 Dr. Heather Cheng - Urgency of germline testing in advanced prostate cancer. Detecting mutations to open up personalized treatment options. 🔬 #GeneticsInCancer
2. 🌐 Dr. Ana Aparicio - Impact of non-DDR genomic alterations on prostate cancer management. Emphasizes the importance of biomarkers for FDA-approved targeted drugs. #ProstateCancerCare
3. 📊 Dr. Himisha Beltran - Differentiating aggressive variants of castrate-resistant prostate cancer. Stresses the need for combined strategies to address both AR-driven and non-AR-driven diseases. 🧬 #OncologyResearch
4. 🚀 Dr. Andrew Armstrong - Discusses treatment for neuroendocrine and aggressive variants, highlighting platinum combinations and the need for genomic testing for targeted therapies. 🧪 #AdvancedProstateCancer
5. 🛠️ Dr. Matthew Smith - Challenges in sequencing chemotherapy and PSMA radioligand therapy. Discusses the potential superiority of 177Lu-PSMA-617. #CancerTreatment
6. 🔬 Dr. Michael Hofman - Comparison of alternative PSMA ligands for diagnostics and treatment. Equivalence between 68Ga-PSMA-11 and 18F-DCFPyL discussed. #DiagnosticImaging
7. 📝 Dr. Stefano Fanti - Utilizing CT findings in PSMA PET/CT. Discusses challenges with false positives and the importance of acting based on high detection rates of PSMA PET. #MedicalImaging
🌍 Each presentation underscores the crucial need for genomic evaluation and personalized therapy in managing prostate cancer.
👨🎓👩🎓💬@neerajaiims @ravikanesvaran @scserendipity1 @EfstathiouEleni @SandhuShahneen @ChrisSweens1 @DrSpratticus @soulehoward1 @nealshore @RobertReiterMD @DRathkopf @ColinCPritchard @piet_ost @WilliamOhMD @ProfJOSullivan @DrPaulNguyen @NDowJames @VedangMurthy @declangmurphy @dmukherji @tompowles1 @brian_rini @mrabti_hind @CaPsurvivorship @DrRanaMcKay @MatikainenMika @quimmateo @LoebStacy @Prof_Nick_James @DrMHofman @montypal @DrDanielHeng @apolo_andrea @DrChoueiri @PGrivasMDPhD @TiansterZhang @HHammersMD @sonpavde @drenriquegrande @BraunMDPhD @yekeduz_emre @GGrisay @fabioturco92 @urotoday @ZilliThomas
@gu_onc
#OncologyUpdate #APCCC2024 – at Bellevue, Suisse
aurelius omlin retweeted
And it’s a wrap! It’s been a wonderful and exciting conference. Thanks @Silke_Gillessen @AOmlin and @APCCC_Lugano !
Let’s meet all in 2026 for #APCCC26
And next year for APCCC Diagnostics led by @ProfKHerrmann and @stefanofanti4
#APCCC24
aurelius omlin retweeted
It has been a fantastic @APCCC_Lugano meeting. Already looking forward to APCCC 2026!
aurelius omlin retweeted
Thanks Yüksel, was wonderful to have you with us!
A heartfelt thank you to Silke, Aurelius, and all the APCCC staff for organizing such an excellent meeting. Your commitment to excellence shone through, making the event not only successful but also memorable. Your hard work and dedication to every detail truly made a difference!💐👏😘
#APCCC24 @APCCC_Lugano @Silke_Gillessen @AOmlin @OncoAlert @uromigos #ProstateCancer #oncology

















































