Model Matters: Genetic Architecture and Cardiovascular Physiology in Translational Medicine

Fibro‐Adipogenic Progenitors From Skeletal Muscle Enhance Microvascular Angiogenesis in a 3D Model

Fibro-adipogenic progenitors (FAPs) are skeletal muscle stem cells that reside between fibers and near capillaries. However, relatively few studies have investigated interactions between FAPs and...

Frontiers | Editorial: Investigating the role of extracellular vesicles in cardiovascular disease...

As key mediators of local and distant intercellular communication, extracellular vesicles (EVs) have emerged as an increasingly important focus in cardiovasc...

Thrombogenicity of stent graft materials as a potential contributing factor to limb graft occlusions

Limb graft occlusions (LGOs) remain a significant complication after endovascular aneurysm repair. Several clinical risk factors have been recognized, but these do not fully account for the consist...

Effect of Shear-Induced Macrophage Secretome on Endothelial Permeability

Discrete subaortic stenosis (DSS) is a pediatric cardiovascular disease marked by fibrotic growth within the left ventricular outflow tract (LVOT), leading to severe complications, including left...

Patient-Specific Analysis of Ventricular Vortex Formation and Flow Energetics in Rheumatic and...

Annals of Biomedical Engineering - Mitral stenosis (MS) accounts for 12% of cardiac patients with single valve disease. There are two main causes: rheumatic disease of the mitral valve (MV) and...

Loss of Chromosome Y and Risk of Abdominal Aortic Aneurysm

This cohort study evaluates the association between loss of chromosome Y and the incidence of aortic aneurysm based on anatomic location.

Comprehensive In Vitro Profiling Demonstrates Successful Immune Evasion of Bioengineered Immune‐S...

Living donor heart valves offer superior durability for pediatric patients but trigger immune rejection. Lentiviral delivery of viral immune-evasion genes US2 and Serpin b9 into donor valve cells...

Remnant virus proteins sustain vascular inflammation post coronavirus infection in mice and humans

Abstract. SARS-CoV-2 coronavirus infections are associated with long-term vascular dysfunction, yet the drivers remain unclear. We hypothesized that remnant Betacoronavirus antigens remain in...

Frontiers | Bioprosthetic heart valve degeneration: new insights into structural remodeling and...

Bioprosthetic heart valves (BHVs) are widely used to treat aortic valve disease, and their demand is rising. However, BHV lifespan remains limited by degener...