Angelique Deleris (@AtDeleris) header
Angelique Deleris (@AtDeleris) profile picture
Joined August 2017
Angelique Deleris retweeted
Our new study on characterizing plant DNA methylation reader proteins, led by @jon_cahn and @JamesPBLloyd, and great collaboration with the Michiel Vermeulen and @ahmillar9 groups genome.cshlp.org/content/ear…
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Our long standing review on T-DNA epigenetic regulation during plant transgenesis and pathogenesis is finally out ! Congrats @joaquinfrp for all the work reviewing the littérature since 1982! Such a fascinating mobile element and complex regulation! track.smtpsendmail.com/90321…
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Angelique Deleris retweeted
Very happy and proud to share the preprint of our integrative study revealing a unique mechanistic framework for a chromatin switch mediated by a dual trxG/PcG factor. Made possible thanks to the work and dedication of several PhD students & postdocs, and fruitful collaborations.
The dual trxG/PcG protein ULTRAPETALA1 modulates H3K27me3 and directly enhances POLYCOMB REPRESSIVE COMPLEX 2 activity for ... biorxiv.org/cgi/content/shor… #biorxiv_genetic
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Spécial thanks and congrats to Valentin Hure for his great work and thanks ANRJCJC for funding that was fruitful!
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3) Our work further reveals a new function of active DNA demethylation in modulating H3K27me3 levels in vegetative tissues, which we confirmed via targeted DNA methylation experiments.
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Together, our results uncover a novel crosstalk between DNA methylation and Polycomb at TEs and reveal that these pathways, thought to be specialized and antagonistic, can be interdependent and cooperate more than anticipated to maintain genome/epigenome integrity in eukaryotes.
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An atlas of conserved transcription factor binding sites reveals the cell type-resolved gene regulatory landscape of flowering plants biorxiv.org/cgi/content/shor… #biorxiv_genomic
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Angelique Deleris retweeted
Last week to register for the @epiplant / @SEBiology symposium on Plant Epigenetics, @GReD_Clermont Clermont-Ferrand, France, July 10-12, 2024. Program & registration ➡️epiplant-seb-2024.sciencesco… Deadline 30th of April!
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Angelique Deleris retweeted
Hello world! We are looking to hire : - a Master 2 student (with possibility for a PhD) contact: chloe.girard [a] i2bc.paris-saclay.fr - Lab engineer (molecular biology and microscopy) apply here: emploi.cnrs.fr/Gestion/Offre… Details on the project: cordis.europa.eu/project/id/…
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Angelique Deleris retweeted
The last 100% home made story about (epi)genome surveillance interplays 🌱🧬☀️…Enjoy !!!!! The histone demethylase JMJ27 acts during the UV-induced modulation of H3K9me2 landscape and facilitates photodamage repair | bioRxiv biorxiv.org/content/10.1101/…
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💥Our new preprint! Transposon ADDICTION in development! Gag proteins of endogenous retroviruses are required for zebrafish development Study led heroically by @sylviaandbu & @JN_Wells This work has transformed my view of transposons, no less! 🧵1/n biorxiv.org/content/10.1101/…
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Angelique Deleris retweeted
Happy to share our preprint: biorxiv.org/cgi/content/shor…
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We show i) that some TEs are targeted by H3K27me3 (Polycomb) instead of DNA methylation in wildtype Arabidopsis ii) H3K27me3 can be deposited on newly inserted TE sequences iii) the existence of “bifrons” TEs that are marked by DNA methylation or H3K27me3 depending on the ecotype
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In sum, we document an alternative control of TEs by H3K27me3 which is more plastic than DNA methylation, and that a TE can change epigenetic silencing state throughout its lifespan. This challenges the dogma that Arabidopsis TEs are solely targeted by DNA methylation in nature.
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