Dev Majumdar (@BcellD) header
Dev Majumdar (@BcellD) profile picture

Majumdar Lab. Fun with B cells and RNA. Here to help anyone doing science.

Burlington, Vermont
Joined May 2020
Photo by Dev Majumdar (@BcellD)Photo by Dev Majumdar (@BcellD)Photo by Dev Majumdar (@BcellD)Photo by Dev Majumdar (@BcellD)Photo by Dev Majumdar (@BcellD)Photo by Dev Majumdar (@BcellD)Photo by Dev Majumdar (@BcellD)Photo by Dev Majumdar (@BcellD)Photo by Dev Majumdar (@BcellD)
Dev Majumdar retweeted
Replying to @bioalgorithmist
I'm not referring to any particular tool. I'm referring to how scientists are presenting their science and that of others. It's getting so bad that it's impossible for any non-domain expert to believe anything anyone claims. This is extremely troubling for credibility of science.
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Excellent example of the core issue I was trying to get at wrt "virtual cells" - optimizing a prediction objective will not necessarily provide an accurate representation of physical or biological phenomena. It's extremely important to be very clear about this. 1/
Can an AI model predict perfectly and still have a terrible world model? What would that even mean? Our new ICML paper formalizes these questions One result tells the story: A transformer trained on 10M solar systems nails planetary orbits. But it botches gravitational laws 🧵
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Dev Majumdar retweeted
TIL the best way to spread misinformation is by presenting it in LaTeX
This quoted post is unavailable.
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✅ @Harraz_Lab has an open lab technician position ✅ Highly motivated individuals with relevant experience are encouraged to apply. uvmjobs.com/postings/75843 📢 We explore brain blood flow, physiology and pathophysiology of ion channels. Learn more harrazlab.com Plz RT
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Dev Majumdar retweeted
NYC's public college system paid Oracle ~$600M to build our course management portal. It's built on top of Oracle's PeopleSoft suite, which they refused to customize without an extra $400M (to hit $1B). New Yorkers got the image below and pay $5M+ / year for *hosting*.
WHAT. DOES. ORACLE. DO???????
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Fascinating study @NatureComms from @RohacsTibor showing that phosphatidic acid can regulate PIEZO2, the mechanosensitive ion channel — and so glad to see yet another application “in the wild” of optoPLD, @ReikaTei’s optogenetic membrane editor for phosphatidic acid! #lipidtime
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Dev Majumdar retweeted
Tried to express and purify your own Tn5 transposase only to run into stability or activity issues? Our new @biorxiv preprint describes OpenTn5: a robust, high-yield protocol for producing a stable pG-Tn5 transposase fusion. Spearheaded by @Jan_Soro. biorxiv.org/content/10.1101/…
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Dev Majumdar retweeted
We posted a new preprint (biorxiv.org/content/10.1101/…). We've been thinking about how to characterize TF function. One challenge is that function and occupancy are difficult to disentangle. We use a simple model and a simple system to test how promoter features change function.
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Replying to @dieworkwear
Some can pull it off
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Dev Majumdar retweeted
We are looking for postdocs interested in working on this project to engineer polyclonal vectored antibody delivery!
Ragon faculty member Alejandro Balazs, PhD, has been awarded a prestigious Avant-Garde Award for HIV and Substance Use Disorder Research from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH). #HIV #Research #NIDA #NIH #Award
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Dev Majumdar retweeted
I am recruiting graduate students, postdocs, and research staff. The future of vascular physiology research is bright, and I'm excited to fill the space with amazing people & discoveries.
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I am beyond proud of our McGill iGEM team, who won the Grand Prize, Best Therapeutics Project, Best Part Collection and Best Presentation Special Prizes in the undergrad category of #iGEM2023 competition. Well done all! Together, we can do it! @McGill_Eng @BioengMcGill
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Undergrad McGill: Through their project “Proteus”, they created a modular system of chimeric fusion proteins that kills cancerous cells while sparing healthy cells that could expand the treatment options for pancreatic cancer patients. 6/9
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Please check up on folks around you. Most folks around who read the news are struggling but some people are ‘really’ struggling. Be the obnoxious boss or colleague who does not take “fine!” for an answer. Dig deeper. Keep Kleenex handy. – at Morrisville, NC
College kids will encounter identity politics as they grow up and venture out into the world. What is not acceptable is if the ugly side of identity politics jeopardizes their lives and well being; you are failing if you allow this or think this to be acceptable, no matter what.
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We’re hiring and looking for incredibly motivated people who want to join us in massively accelerating biomedical research. Check out our openings for Head of ML and Head of Data! boards.greenhouse.io/incubat… boards.greenhouse.io/incubat…
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Dev Majumdar retweeted
Why does installing a minimal conda environment in github actions take upward of 35 minutes? It is 2023, is it not? Have we boiled the oceans for this....
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Mount Mansfield, Vermont’s highest summit, sees its first inch of snow this season dlvr.it/SxrXyS
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Super fun to be featured along with my @uvmvermont @UVMLarnerMed colleagues (@poisondartfrog7 , @jwocro , and Jason Botten) on the most recent episode of TWiV (#1055) with the one and only @profvrr : microbe.tv/twiv/
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Mahishasuramardini" marks the commencement of Debi Pokhkho, the period when it is believed goddess Durga descends from Kailash to visit her parental home on earth. The story of how this magnum opus was brought to life, amidst debate and hate mails, is no less interesting. 1/22
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Dev Majumdar retweeted
Animation of Gbeta5 folding by the CCT protein folding machine. Multiple snapshots were recovered from cryo-EM image processing, which revealed the step-by-step folding trajectory of its beta-propeller fold. Paper link: dlvr.it/SxZ31g. Animation by @MargotRiggi
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