Organoids culture, 3d imaging and image analysis. Biomedical applications and extreme conditions. #organoid

Singapore
Joined February 2022
A universal AI-powered pipeline developed by @Beghinteam enables precise 3D analysis of cell morphology and topology within organoid structures. nature.com/articles/s41592-0…
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Our #CellLineOfTheWeek is SOX-2 - our first cell line to go into space! 🚀 Last year, @axiom_space and @CSRegenMedicine researchers @ArunSharmaPhD and @CliveSvendsen sent SOX-2 to the @ISS_CASIS to study stem cell production in microgravity. More: cedars-sinai.org/newsroom/mi…
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Hi everyone, check this : dlvr.it/SyZRRP Hopefully you will enjoy it !Have fun with organoids...always. #organoids #microscopy @MBIsg @BeghinTeam
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Innovative 3D segmentation of #organoids + datamining software = OrganoProfiler(?) @MBIsg @QuantaCell_SAS
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Zero-G Wells: Taking Mechanobiology into Space - Mechanobiology Institute, National University of Singapore mbi.nus.edu.sg/news/zero-g-w…
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Thanks to #po_strale for this 'Organoid-onaut' montage made from our 3D images of our #organoids (batch of thousands brave organoids ! Keep calm and #AI). #SpaceBiology #GSTC2023 #SgSpace #AsiaSpace #spaceindustry
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Tout est question de perspective... La Lune éclipsait la Terre hier alors que @NASA_Orion se trouvait à plus de 430 000 km de notre planète. Ces incroyables images sont prises par les caméras situées aux extrémités des panneaux solaires du Module de service européen #OrionESM.
OK... so this capture from the live Artemis stream is simply bonkers. Wowza! Orion Spacecraft is approaching the farthest distance from Earth
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Interview with @BeghinTeam and Gianluca Grenci with @UZHspacehub about testing their ZeroG-Well technology for growing organoids in microgravity on the latest Swiss parabolic flight campaign. youtu.be/w3c0Z_nSGUU
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Replying to @BeghinTeam
@BeghinTeam and Gianluca all suited up for their parabolic flight!
Replying to @UZHspacehub
🔬 Prof. Anne Beghin from the National University of Singapore tests her newly developed “ZeroG Wells” for building, development, and analysis of organoids in #microgravity during the ongoing Swiss Parabolic Flight Campaign. @MBIs @UZH_en @NLR_NL @BeghinTeam
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I had an exicting day today ! xitter.cf/UZH_en/status/15779710… More info and pictures to come from our first zero G experiments !
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New paper from the lab! We developed an optogenetic tool, OptoShroom3, to induce apical constriction in illuminated cells(left). By controlling cell shapes, OptoShroom3 can induce tissue shape changes, including lumen shrinkage of neural organoids(right). doi.org/10.1038/s41467-022-3…
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And I discover that we shared the same volume with the wonderful TrackMate7 paper from D.Ershov. Congrats again to JYTinevez and GJacquemet teams ! I still like sometimes the real paper version...
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Back to work...some paper gift!
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How does the complex internal structure of an organ emerge during development? Happy and relieved to see our attempt to answer this just out: authors.elsevier.com/sd/arti… Below, I give an overview of the paper and the key results (1/21)
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Wait for it bis !Our JeWells as the cover of Nature methods ! Fantastic work of Diego Pitta de Araujo for the illustration. "Volume 19 Issue 7, July 2022" nature.com/nmeth/volumes/19/…
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Wait for it ....Our new Nature method on #organoids is published ! a lot of efforts including multidisciplinary teams, from #microfabrication, #stemcells biology, cutting edge #microscopy, image analysis & #AI !Congrats to all for this tremendous work ! nature.com/articles/s41592-0…
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Organoids as Hubble galaxies #sciart #microscopy #colonoid #confocalbloopers 1/♾
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