@BiVictriX

Exploiting the Bi-Cygni technology, delivering a new class of biotherapeutics with superior selectivity. https://xitter.cf/t.co/n0JxAV5xPV

 Macclesfield, England
bivictrix.com
Joined May 2021
  • Tweets170
  • Following469
  • Followers180
83Media
🚀 Exciting news from BiVictriX! Our lead solid‑tumour ADC, BVX002, has delivered tumour growth inhibition and regressions in an AZD8205-resistant mouse 🎯 New data shows that a single dose of BVX002 reverses tumour growth in an AZD8205-resistant mouse 🌟
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In a mouse unresponsive to AstraZeneca’s B7H4-TOPOi-based ADC, AZD8205, a single dose of BVX002 was not only able to reverse the exponential growth of the tumour but also resulted in tumour regressions of >62% in just 14 days!
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These compelling results demonstrate the potential of BVX002 to deliver meaningful efficacy where other B7-H4-targeted ADCs fall short. To read more about this study, visit our website.
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🚀 Preclinical win for #BiVictriX: Our bispecific ADC, BVX002, outperformed 2 B7H4-targeted competitors (Pfizer’s SGN-B7H4V* & AZ’s AZD8205*) in head-to-head studies. 📊 Tumor regressions across all doses tested. 👇 More on why this matters:
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✅ Our Bi-Cygni® platform breaks through expression thresholds that limit conventional ADCs. 🧬 Precision, potency, and consistent DAR4 from our site-specific conjugation tech. We’re setting a new bar in #ADC innovation.
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🔗 Read the full press release for the data & context: lnkd.in/evbRu9Fa #Oncology #Biotech #PharmaInnovation #BispecificADC

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🔬 At BiVictriX, we’re not confined to 1 ADC design philosophy. Our BVX002 programme employs an innovative “AND/OR”-gated bispecific ADC to tackle ovarian cancer's tumour heterogeneity. It’s about clinically relevant solutions, not just being different. #ADC #bispecific #oncology
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We’ve got MORE exciting data to share with you! 🚨 Our latest pre-clinical study found that BVX001 increased survival rates in acute myeloid leukaemia (AML) by 126% compared to an untreated control group. Find out more: bivictrix.com/news/extended-… #AML #BloodCancer #antibodies
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@BiVictriXTherapeutics retweeted
Proactive
@proactive_x24 Aug 2023
$BVX Bivictrix Therapeutics progress attracting interest, says CEO tinyurl.com/22q2gvfu @bivictrix $BVTXF #BVX #BVTXF

BiVictriX Therapeutics progress attracting interest, says CEO

Markets and small-cap news.

themarketreporter.co.uk
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We're pleased to announce our lead asset, BVX001, has been granted a US patent! This is a big step on BiVictriX's journey, providing broad protection for our lead therapeutic asset at the antigen level. Find out more: bivictrix.com/news/us-patent… #bloodcancer #AML #ADC #biotech

US Patent Granted Providing Broad Protection for BVX001 - Bivictrix

THE INFORMATION CONTAINED WITHIN THIS ANNOUNCEMENT IS DEEMED BY THE COMPANY TO CONSTITUTE INSIDE  INFORMATION AS STIPULATED UNDER ARTICLE 7 OF THE EU REGULATION 596/2014 AS IT FORMS PART OF THE UK...

bivictrix.com
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Is the accepted dogma around the therapeutic window of #ADCs in need of a rethink? In their recent paper, Columbo and Rich highlight the mounting clinical evidence that suggests ADCs do not significantly increase the MTD of their conjugated drugs: cell.com/cancer-cell/pdf/S15…
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Discover how our clinical lead candidate, BVX001, addresses some of the shortcomings of current antibody drug conjugate (ADC) treatments for acute myeloid leukaemia in this in-depth article in @Labiotech_eu labiotech.eu/in-depth/bivict… #ADC #AML #pipeline #biotech

Antibody drug conjugates: BiVictriX drives a new era in cancer medicine

In the race to develop safe cancer therapies, BiVictriX is developing a targeted treatment for acute myeloid leukemia with a bispecific ADC.

labiotech.eu
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@BiVictriXTherapeutics retweeted
LUKA GLOBAL GROUP@lukaglobal27 Jul 2023
Antibody drug conjugates: BiVictriX drives a new era in cancer medicine - zurl.co/ai4z

Antibody drug conjugates: BiVictriX drives a new era in cancer medicine

In the race to develop safe cancer therapies, BiVictriX is developing a targeted treatment for acute myeloid leukemia with a bispecific ADC.

labiotech.eu
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@BiVictriXTherapeutics retweeted
Proactive
@proactive_x17 Jul 2023
$BVX BiVictriX sees positive final data in BVX001 leukaemia drug study tinyurl.com/2kuo5gml @bivictrix $BVTXF #BVX #BVTXF
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We’re delighted to share positive final data in the preclinical efficacy study of BVX001, our lead Bi-Cygni® bi-specific ADC for AML. Find out more: linkedin.com/feed/update/urn… #ADC #AML #pipeline #Drugdevelopment
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With Cancer Immunotherapy Month coming to an end, we wanted to highlight another way we are contributing to the development of high-impact cancer therapies. Discover more about our science and pipeline: linkedin.com/feed/update/urn… #CIM23 #Immune2Cancer #immunotherapy
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We’re excited to reveal the positive interim data from our second preclinical efficacy study of BVX001 — our lead ADC programme for AML - in larger tumours. Read more: bivictrix.com/news/positive-… #ADC #AML #Biotech #pipeline #antibodytherapeutics #oncology #drugdevelopment
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@BiVictriXTherapeutics retweeted
Proactive
@proactive_x19 Jun 2023
$BVX BiVictriX Therapeutics data underscores the potential of leukemia drug tinyurl.com/23lbj668 @bivictrix $BVTXF #BVX #BVTXF

BiVictriX Therapeutics data underscores the potential of leukemia drug

Markets and small-cap news.

themarketreporter.co.uk
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@BiVictriXTherapeutics retweeted
Proactive
@proactive_x6 Jun 2023
$BVX BiVictriX Therapeutics shares close 7% higher after making preclinical progress tinyurl.com/2n9za589 @bivictrix $BVTXF #BVX #BVTXF
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