@BioWorldScience

Essential discovery and preclinical research news to support crucial drug R&D decisions at the earliest stages.

bioworld.com/topics/520-bioworld-science
Joined May 2022
  • Tweets1.1K
  • Following2
  • Followers86
38Media
Alzheimer’s blood tests mean earlier diagnosis, new type of patient bioworld.com/articles/734888… #biomarkers #neurology #diagnostics #research @WorldDementia

Alzheimer’s blood tests mean earlier diagnosis, new type of patient

New blood-based biomarker tests that detect Alzheimer’s before symptoms appear are poised to transform the clinical landscape by catching the disease when controlling for risk factors is known to...

bioworld.com
11
#UEGWeek: Early antibiotic exposure linked to IBS in adulthood (free w/ registration) bioworld.com/articles/734808… #gastrointestinal #preclinical #research #science #news

Early antibiotic exposure linked to IBS in adulthood

At the United European Gastroenterology Week (UEGW) 2026 annual conference being held in Barcelona Oct. 17-20, a team of researchers from the Karolinska Institutet, the Sahlgrenska University...

bioworld.com
1
2
202
Duke takes digital twins from snapshots to living models (free w/ registration) bioworld.com/articles/734757… #preclinical #research #science #news

Duke takes digital twins from snapshots to living models

A decade ago, Amanda Randles and her colleagues could use a supercomputer to simulate only a few heartbeats through a patient’s cardiovascular anatomy. Duke University researchers now believe they...

bioworld.com
1
3
232
Complete genomes reveal hidden somatic mutations (free w/ registration) bioworld.com/articles/734738… #preclinical #research #science #news

Complete genomes reveal hidden somatic mutations

A consortium funded by the National Institutes of Health (NIH) has unveiled the most comprehensive map of somatic mosaicism to date, uncovering the mutations that arise during development and aging...

bioworld.com
1
12
Moderna designs bispecific antibodies against SARS-CoV-2 variants (free w/ registration) bioworld.com/articles/734705… #COVID19 #preclinical #research #science #news

Moderna designs bispecific antibodies against SARS-CoV-2 variants

Scientists at Moderna Inc. are seeking a solution to the rapid emergence of viral variants that escape treatments. Many monoclonal antibodies (mAbs) initially work well against a single target but...

bioworld.com
1
27
γδ T cells expose hidden immune vulnerability in small-cell lung cancer (free w/ registration) bioworld.com/articles/734675… #cancer #preclinical #research #science #news

γδ T cells expose hidden immune vulnerability in small-cell lung cancer

Researchers have identified gamma delta (γδ) T cells as potent killers of small-cell lung cancer (SCLC), with their genetic signature potentially revealing patients who could benefit from immunothe...

bioworld.com
1
2
261
#ECNP2026: Metabolism could be site of psychiatry’s next breakthrough bioworld.com/articles/734652… #neurology #preclinical #research #science #news

ECNP 2026: Metabolism could be site of psychiatry’s next breakthrough

Psychiatric drug discovery is “ready for transformation 2.0,” Roger McIntyre told his audience at the annual congress of the European College of Neuropsychopharmacology (ECNP) this week. “I believe...

bioworld.com
1
1
226
Pathogen-activated PROTACs to target chronic infections (free w/ registration) bioworld.com/articles/734601… #infection #preclinical #research #science #news

Pathogen-activated PROTACs to target chronic infections

Persistent mycobacterial infections may depend on senescent macrophages that provide a long-term intracellular refuge to survive as a reservoir. Based on this concept, researchers from the University...

bioworld.com
1
5
255
P2Y2 activation reverses #autism symptoms in mice (free w/ registration) bioworld.com/articles/734568… #neurology #preclinical #research #science #news

P2Y2 activation reverses autism symptoms in mice

A team of researchers from The Ottawa Hospital Research Institute shed some light on a potential association between the chromosome 16p11.2 deletion observed in autism, endothelial dysfunction and a...

bioworld.com
1
22
#NobelPrize in Chemistry goes for chiral molecules (free w/ registration) bioworld.com/articles/734541… #preclinical #research #science #news

Nobel Prize in Chemistry goes for chiral molecules

The Royal Swedish Academy of Sciences has awarded the 2026 Nobel Prize in Chemistry to Henri Kagan and Kenso Soai for discoveries that transformed asymmetric organic synthesis, a field dedicated to...

bioworld.com
1
1
232
Gamma delta T-cell receptor bridges innate and adaptive immunosurveillance (free w/ registration) bioworld.com/articles/734520… #immune #cancer #preclinical #research #science #news

Gamma delta T-cell receptor bridges innate and adaptive immunosurveillance

A study has analyzed the role of gamma delta T lymphocytes (γδ T cells) in immunosurveillance against tissue damage and cancer. This specialized immune cell population combines features of both...

bioworld.com
1
35
2026 #NobelPrize honors work shining light in and on brain circuits (free w/ registration) bioworld.com/articles/734472… #neurology #preclinical #research #science #news

2026 Nobel honors work shining light in and on brain circuits

The Nobel Assembly at Karolinska Institutet announced today that it has awarded the 2026 Nobel Prize in Physiology or Medicine to three scientists “for their discoveries concerning light-gated ion...

bioworld.com
1
1
259
Mitochondrial cardiolipin loss drives muscle adaptation in #aging (free w/ registration) bioworld.com/articles/734453… #musculoskeletal #preclinical #research #science #news
2
35
#EASD2026: rebuilding the pancreas: new paths to restoring β cells (free w/ registration) bioworld.com/articles/734412… #preclinical #research #science #news

EASD 2026: rebuilding the pancreas: new paths to restoring β cells

Efforts to restore the pancreas’ insulin-producing capacity are moving beyond glucose control and toward regeneration. At the European Association for the Study of Diabetes (EASD) meeting, several...

bioworld.com
1
1
2
63
#EASD2026: Beyond incretins, new targets reshape metabolic drug development (free w/ registration) bioworld.com/articles/734387… #preclinical #research #science #news

EASD 2026: Beyond incretins, new targets reshape metabolic drug development

At the ongoing European Association for the Study of Diabetes (EASD) meeting, researchers showcased a new generation of experimental therapies that move beyond traditional appetite and insulin...

bioworld.com
2
293
Menopause blood proteins linked to dementia risk (free w/ registration) bioworld.com/articles/734369… #womensheatlh #aging #neurology #preclinical #research #science #news

Menopause blood proteins linked to dementia risk

Menopause has long been linked to a higher risk of cognitive decline and Alzheimer’s disease (AD) later in life, but the mechanisms behind that connection are poorly understood. To address this...

bioworld.com
13
Blood DNA flags cancer risk years before diagnosis (free w/ registration) bioworld.com/articles/734310… #diagnostics #cancer #preclinical #research #science #news

Blood DNA flags cancer risk years before diagnosis

A team of researchers from the University of Toronto and Oxford Population Health have shed some light on the interpretation of plasma cell-free DNA methylation signatures that could be associated...

bioworld.com
1
23
Development uncovers EDA2R as a key senescence regulator (free with registration) bioworld.com/articles/734272… #preclinical #research #science #news

Development uncovers EDA2R as a key senescence regulator

Cellular senescence is commonly associated with aging, but it also plays essential roles during embryonic development. Scientists at the Institute of Genetics and Molecular and Cellular Biology...

bioworld.com
1
25
IL-21 mimetic drives durable remission in PDAC (free w/ registration) bioworld.com/articles/734242… #cancer #preclinical #research #science #news

IL-21 mimetic drives durable remission in PDAC

Despite decades of effort, pancreatic ductal adenocarcinoma (PDAC) has remained largely resistant to immunotherapy. The emergence of KRAS inhibitors marked a long-awaited breakthrough, delivering...

bioworld.com
1
144
Host-directed therapies can shape microbial resistance (free w/ registration) bioworld.com/articles/734223… #infection #preclinical #research #science #news

Host-directed therapies can shape microbial resistance

Researchers at the National Institutes of Health (NIH) have shown that the host-targeted immunosuppressive drug mycophenolic acid (MPA) is a contributor to drug resistance in the fungal pathogen...

bioworld.com
1
133
Load more