“I ❤️ Cholesterol; but my ❤️ doesn’t” However, there’s much much more to cholesterol than that. We study how we and our cells balance this Jekyll/Hyde molecule
Sydney, New South Wales
Joined September 2018
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Brown Lab UNSW retweeted
One of the best things about science is speculating on how to solve a fascinating problem.
Check out our paper "A paREDOX in the control of cholesterol biosynthesis" in #BioEssays.
doi.org/10.1002/bies.2024000…
@UNSWScience @UNSWBABS (1/3)
Brown Lab UNSW retweeted
Thrilled to have the final pieces of my PhD work with @BrownLabUNSW published in @jbiolchem - huge thanks go to @TinaBNguy for the effort to get it across the line after my departure for the UK, and also to @ximingDu for the beautiful microscopy! (🧵1/4) doi.org/10.1016/j.jbc.2024.1…
Brown Lab UNSW retweeted
Very excited to uncover SC5D as the 6th cholesterol synthesis enzyme targeted by our favourite E3 ligase MARCHF6! Check out our findings in
@BBAjournals
doi.org/10.1016/j.bbalip.202…
@UNSWScience
Brown Lab UNSW retweeted
CO2, regulation and metabolism. @NicoleMFenton @BrownLabUNSW explore a #PLOSBiology study that provides the first link between #CarbonDioxide and the master transcriptional regulator of #cholesterol homeostasis. Paper: plos.io/3QEDs7f Primer: plos.io/46sLSV2
Our latest paper just out! @NatMetabolism – at Sydney, New South Wales
Check out our commentary on the latest landmark study from Peter Tontonoz's group @UCLA! A staggering amount of work solidifying the role of plasma membrane-to-ER #cholesterol transport in systemic lipid balance. doi.org/10.1038/s42255-022-0… @BrownLabUNSW @UNSWBABS @UNSWScience
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Brown Lab UNSW retweeted
Great way to end the year with my first first-author publication - a mini-review looking at the interplay between sugar and cholesterol metabolism. @UNSWScience🧵(1/3)
sciencedirect.com/science/ar…
A new way to control our favourite E3 ligase MARCHF6! With our lab neighbours @voineagulab @akira_gokool, we found MARCHF6 forms a circRNA to control protein levels of itself and its substrate SM. New publication by @qian_lydia and @laurajsharpey out now! authors.elsevier.com/a/1fuio… – at Sydney, New South Wales
Last presentation for the Brown Lab at @ComBio2022 Nicole Fenton! @NicoleMFenton #combio2022 – at Melbourne, Victoria
Now we have Isabelle Capell-Hattam presenting her work from her recently submitted PhD thesis! @isabelle_CapHat #combio2022 – at Melbourne, Victoria
Posters by Lydia Qian and Laura Sharpe on now! #combio2022 @qian_lydia @laurajsharpey – at Melbourne, Victoria
Brown Lab is excited to be at @ComBio2022! There are six presentations from our lab over the next three days. Please feel free to reach out if you want to chat with us! #combio2022 – at Melbourne, Victoria
On Friday, @isabelle_CapHat at 10:30 am in Eureka Room 2, @NicoleMFenton at 4:10 pm in Hospitality Suite 1, and @TinaBNguy at poster 212. – at Melbourne, Victoria
Brown Lab UNSW retweeted
A big milestone today with @BrownLabUNSW celebrating 20 years with @UNSWScience !!!
It is amazing to think how many young researchers have walked through the lab and emerged as actual real life scientists thanks to Andrew's mentoring and guidance.
Early signals of spring in Sydney bring the @BrownLabUNSW out for icecream. – at Sydney, New South Wales
Lab meeting in lockdown with a random pet thrown in for good measure @UNSWBABS @UNSWScience
We are saddened to say goodbye to @Nicola_A_Scott who’s been with the lab for five years (Hons + PhD), and wish her all the best as she takes up an exciting post-doc in @Neal_Lab. Nicola is modelling her PhD artwork (the many tentacles of an E3 ubiquitin ligase).
