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Cocaine has overtaken fentanyl as the drug most often involved in Cuyahoga County, Ohio, overdose deaths for a second year. County projections for 2026 put cocaine involvement at 200 of 340 deaths and fentanyl at 130, but categories overlap because many deaths involve multiple drugs. Overdose prevention needs to reflect a changing local drug supply, including risks to people who may not expect opioids in cocaine.

A prodrug is a substance that undergoes chemical transformation inside the body to produce another active compound. In the case of 1P-LSD, enzymes remove its additional propionyl group, converting it into LSD. This helps explain why a substance with different molecular properties can produce similar effects.

MGM-15 and MGM-16 remain temporarily in Schedule I. The DEA’s October notice proposes maintaining those controls while separating the compounds from a different action on mitragynine pseudoindoxyl.

We LOVE tools that help create safer nightlife experiences. 🫶 That’s why we encourage everyone to Triple Check their substances before use: 🔍 SCREEN with test strips to check for potential adulterants. 🧪 IDENTIFY with multiple reagent tests to help determine what may be present. 📲 VERIFY your results using the free Transparency Harm Reduction app to compare reactions and access harm reduction resources. No single test can guarantee safety, but using multiple tools helps you make more informed decisions. Learn more at BunkPolice.com or TransparencyTesting.com

Georgia Poison Center’s director reported 315 calls and four deaths involving kratom-like products this year. He said approximately 80% of calls involved hospitalization. Lab analysis and toxicology reports are needed to distinguish concentrated or synthetic compounds within the kratom-like products.

Beginning December 12, 2026, covered New York private employers must make opioid-overdose reversal medication available at work. The requirement applies to employers subject to federal workplace first-aid supply requirements. Government employers are exempt. Proposed regulations include accessible placement, sufficient doses, replacement of expired supplies, and at least one trained employee on-site during business hours.

EMA’s medicines committee recommended removing Nyxoid’s prescription requirement, potentially widening access to naloxone nasal spray. For now, this is a committee recommendation, not confirmation of immediate prescription-free availability.

1P-LSD first appeared on the recreational drug market around 2015. Unlike some earlier LSD derivatives, it had not been documented in scientific or patent literature before appearing as a recreational substance. Researchers subsequently began investigating its chemistry, pharmacology, and metabolism.

Los Angeles County announced its first confirmed cychlorphine-related fatality on October 15th. The death occurred in February 2026, but substance confirmation has just been made.

Utah linked four deaths from October 5th to potent compounds found in supplements sold as “cat’s claw” and kratom products, including the brand Buzzers. Testing identified pseudoindoxyl and MGM-15.

The DEA has issued a notice of intent addressing 7-OH and mitragynine pseudoindoxyl. Proposed controls include concentrations above 1 mg/g in solids or 1 mg/mL in liquids, or a mitragynine-to-target-compound mass ratio below 100. A new order could be published on or after November 13, 2026. The October notice itself does not enact that order. Existing temporary controls on mitragynine pseudoindoxyl remain effective pending replacement or expiration.

Reagent tests use color-changing chemical reactions to help identify substances in your sample. 🧪 Simply add 1-2 drops of a reagent to a tiny sample and compare the reaction to the included color chart or lab-verified reaction videos on the free Transparency Harm Reduction App.

A secret shopper study had researchers call into 22 licensed Oregon psilocybin centers to examine their screening practices. None of the contacted centers offered unsupervised consumption or dosing without prior psychiatric assessment. No center advised callers taking antidepressants to discontinue them without consulting their physician. The median quoted session cost was $1,900, and none accepted insurance.

A controlled human study found that orally administered 1P-LSD was rapidly converted into LSD. Researchers detected LSD in participants' blood and urine, providing direct evidence that 1P-LSD acts as a prodrug in humans. bunkpolice.com/1p-lsd-vs-lsd…

Colorado’s October 9th Craft vape recall has grown as health complaints have reached 38. An October 13th notice added a batch containing the prohibited pesticide chlorfenapyr. Earlier actions involved methylene chloride contamination and concerns about geraniol’s compliance with ingredient rules.

In a recent study, a low dose of LSD appeared to improve certain measures of attention in women but not men. Women who received the LSD microdose responded approximately 8% faster during a sustained-attention task and experienced fewer lapses in attention. Researchers did not observe a comparable improvement among the men in the study. 🔗 Read the full blog: bunkpolice.com/does-lsd-micr… 🧪 Learn to test LSD and find kits at BunkPolice.com 🔬 Go deeper with lab analysis at TransparencyTesting.com

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Ibogaine is attracting research funding and attention as a possible treatment for opioid use disorder. Early reports suggest potential benefits, but limited clinical evidence and serious cardiac risks remain central obstacles.

Unsafe bacteria, yeast, and mold were found in six flower and pre-roll products from The B Maine dispensary in Lebanon, Maine. None had undergone contaminant testing. The advisory highlights a major gap: Maine’s medical cannabis program lacks the testing and recall requirements that apply to the state's adult-use program products.