Radiologist & Clinician Scientist | Prostate MRI | Oncologic Imaging | Interventional Oncology - Charité Universitätsmedizin Berlin | Berlin Institute of Health
Berlin, Germany
Joined April 2023
- Tweets18
- Following49
- Followers48
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New publication in @JAMANetworkOpen!
Could a single #PSA test in midlife guide risk-adapted #ProstateCancer screening?
We explored this question in a population-based cohort of 2,651 men with a 20-year follow-up.
Find the #OpenAccess paper below🔽
@ChariteBerlin @IvoSchootsNL
Cohort study of men aged 45–70 years found that low baseline prostate-specific antigen (PSA) was associated with low long-term #ProstateCancer risk, supporting risk-adapted screening strategies.
ja.ma/4kbadHy
ALT Two graphs, 'Cumulative incidence of prostate cancer' and 'Cumulative incidence of death', show time in years(y) versus cumulative incidence. Prostate cancer incidence rises sharply for >3.0 ng/mL, moderately for 1.0-3.0 ng/mL, and slightly for <1.0 ng/mL.
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Charlie Hamm retweeted
Oncological Safety of MRI-Informed Biopsy Decision-Making in Men With Suspected Prostate Cancer
jamanetwork.com/journals/jam…
Cohort study evaluated the feasibility and safety of using a community-based MRI diagnostic pathway to avoid prostate biopsy (PB) in men with suspected #ProstateCancer (PCa) based on 3-year monitoring. Conducted across multiple urology practices and imaging centers in Berlin, Germany, the study included 593 men who underwent multiparametric MRI (mpMRI). Nearly half (48%) of the participants had negative MRI results, and 41% avoided PB over three years. Clinically significant PCa (csPCa) was detected in 29% of men after three years.
Study found that men with negative MRI results who avoided biopsy were not at increased risk of csPCa, supporting the safety of an MRI-first diagnostic approach when combined with systematic follow-up.
@Charlie_Charite
@AsbachP
@veerukasi
@CashHannes
@OncoAlert 🚨 @bavilima @nataliagandur @yekeduz_emre
Charlie Hamm retweeted
Most viewed in the last 7 days from @JAMAOnc:
Men with negative multiparametric MRI results avoiding biopsy were not at elevated risk of clinically significant prostate cancer.
ja.ma/3BF8usc
Charlie Hamm retweeted
Happy to share our commentary led by @ProfPadhani on the PROKOMB trial, shorturl.at/gCWSz discussing:
1⃣Long-term safety of avoided Bx: MRI(-)👉≥GG2 4% @3yr)
2⃣Risk stratification
3⃣High-quality reporting
4⃣Re-thinking guidelines
5⃣Implications for AI development
#pcsm
Proud to share our @JAMAOnc study validating the oncological safety of MRI-guided biopsy decisions in suspected #ProstateCancer. A true honor to work with @AsbachP @IvoSchootsNL @veerukasi @CashHannes on this 3-year monitoring study. @ChariteBerlin ja.ma/41vdL02
Charlie Hamm retweeted
Last 2024coffee break ☕️? @Charlie_Charite and the team say "The main finding of this prospective, multisite trial demonstrated that prebiopsy prostate MRI, as an integral component of the MRI pathway, is feasible in a community-based setting and oncologically safe" go read it🔓
Proud to share our @JAMAOnc study validating the oncological safety of MRI-guided biopsy decisions in suspected #ProstateCancer. A true honor to work with @AsbachP @IvoSchootsNL @veerukasi @CashHannes on this 3-year monitoring study. @ChariteBerlin ja.ma/41vdL02
Charlie Hamm retweeted
A well organised, well presented session, with challenging cases at #ESUR24
Congratulations especially to the ESUR-Juniors. You did an excellent job! @AdrianoDiasRad @AilinRadio @JHernandez_RX @Charlie_Charite @vbloegager @Ema_Messina_ @IztokCaglic @ESUR_JN @EsurOffice
An engaging session on prostate #MRI. From #prostatecancer diagnosis and staging to recurrence, while emphasizing the importance of #quality! @AdrianoDiasRad @AilinRadio @JHernandez_RX @Charlie_Charite @vbloegager @JelleBarentsz @Ema_Messina_ @IztokCaglic @ESUR_JN #ESUR24
Charlie Hamm retweeted
Traditions are important - the JN night out! We are growing, huh? @ESUR_JN
#ESUR2024 #lisbon
@giga_fra @MaartendeRooij @panico_camilla @ZawaidehJeries @A_PonsiglioneMD @JHernandez_RX @Charlie_Charite @carnellicarlos @Mart_Pecoraro @lrusso_md @MiriamDolciami
Charlie Hamm retweeted
An engaging session on prostate #MRI. From #prostatecancer diagnosis and staging to recurrence, while emphasizing the importance of #quality! @AdrianoDiasRad @AilinRadio @JHernandez_RX @Charlie_Charite @vbloegager @JelleBarentsz @Ema_Messina_ @IztokCaglic @ESUR_JN #ESUR24
Charlie Hamm retweeted
✅ New ESR Essential in @EurRadiology
➡ Using the right scoring system in #prostate MRI—practice recommendations by #ESUR
🖇 link.springer.com/article/10…
@EsurOffice @ESUR_JN @myESR
Charlie Hamm retweeted
You have something to read ✅
Also, if you are into image based prostate procedures (and you are an ESUR member), you can go see our webinar too! It's available online 😎
esur.org/webinars-2024/
Thrilled to share our new study presenting initial prospective data on AI-guided prostate biopsy management:
authors.elsevier.com/c/1i-uV…
Many thanks to @GuenzelKarsten for the fantastic collaboration! #ProstateCancer @EurUrolFocus @ChariteBerlin @Vivantes @berlinnovation @ESUR_JN
Thrilled to share our new study presenting initial prospective data on AI-guided prostate biopsy management:
authors.elsevier.com/c/1i-uV…
Many thanks to @GuenzelKarsten for the fantastic collaboration! #ProstateCancer @EurUrolFocus @ChariteBerlin @Vivantes @berlinnovation @ESUR_JN
Charlie Hamm retweeted
In this edition of Coffee break, we do an overview of this faltastic article from @charlie_charite about using zone specific PSA density. According to the authors "Using the sPSAD-based BDS, false positives were reduced by 25%" ... Gocheck it out! rdcu.be/dFbkb
Happy to share our new study on transition zone-specific PSAD for prostate biopsy planning.
rdcu.be/dCIrL
⬆️specificity + ↔️sensitivity = ⬆️accuracy in GG2 #ProstateCancer detection
@EurRadiology @ChariteBerlin @ProfPadhani @AsbachP @CashHannes @ESUR_JN
Charlie Hamm retweeted
Commentary: Contrast-medium administration for #prostate MRI - yes! Contrast-medium administration can be abandoned. (@AsbachP, @ChariteBerlin)
#EuropeanRadiology
🔗 buff.ly/3OgYRDG
Great overview by @ProfPadhani on Prostate Cancer Detection Using Artifical Inteligence Software - 2023 Up... youtu.be/JIPsFIpGCBA via @YouTube
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Charlie Hamm retweeted
👉🏼 commentary on DCE positive prostate lesions
👉🏼 read the original paper - very interesting and important!
Are upgraded DCE-positive PI-RADS 3 lesions truly suspicious for clinically significant prostate cancer? pubmed.ncbi.nlm.nih.gov/3715…
