Mitochondrial health expert applying peer-reviewed science to develop evidence-based protocols for human health and longevity. Founder of https://xitter.cf/t.co/p1KbY9pqx8.
Joined October 2009
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Your cells are aging faster than you think.
After age 18, mitochondrial density declines by 1% every year—one of the clearest biological markers of aging.
By 70, you’ve lost more than half your cellular energy capacity.
Here’s what most people miss: this decline isn’t inevitable. 🧵👇
Yes, because bears induce hypothyroidism in themselves in order to hibernate.
Hibernating brown bears have roughly double the cholesterol and triglycerides of healthy humans—yet show no atherosclerosis or heart disease.
During winter hibernation, free-ranging brown bears (Ursus arctos) experience plasma cholesterol levels around 12 mmol/L (versus ~5 mmol/L in humans) and elevated triglycerides, along with obesity, physical inactivity for months, and other metabolic stressors that would typically promote vascular disease in humans.
Histopathology of coronary arteries and aortic arches from adult bears has repeatedly shown no fatty streaks, foam cell infiltration, inflammation, or atherosclerotic lesions—even in animals that have lived through multiple hibernation cycles.
Key protective mechanisms identified in research include:
• LDL particles that are larger and have 5–10× lower affinity for arterial proteoglycans (the binding that helps drive plaque formation in humans)
• Higher plasma cholesterol efflux capacity
• Stabilized or more cardioprotective HDL composition (including increased HDL2b)
• Greater antioxidant capacity and reduced inflammatory/oxidative markers during hibernation
These findings come from multiple studies on Scandinavian brown bears, including work in Scientific Reports, the Journal of Lipid Research, and related papers.
The takeaway is straightforward: high circulating cholesterol and triglycerides do not automatically produce atherosclerosis. Context—lipoprotein structure, function, inflammatory status, and overall metabolic handling—matters. Bears offer a natural model of high lipids without the expected vascular damage.
Not only that, but this morning's news is that when Zelensky misbehaved, Elon slowed down starlink so that their military drones couldn't work.
You might like *that* choice if you didn't like how Zelensky was behaving, but that's also the power to slow down your own internet if *you* misbehave.
The Supreme Court struck down net neutrality regulations last year. That means this is totally legal if it is done in a way that is not deemed discriminatory by civil rights statutes, and possible to do illegally if kept hidden.
This means that as the global control grid consolidates, freedom-loving people are going to have to think a lot more carefully about how to maintain decentralized access to the internet.
THE GLOBAL CONTROL GRID IS BEING BUILT. FOLLOW THE TIC, MIC & FIC.
Everyone is talking about SpaceX potentially merging with Tesla.
But I think they’re missing the bigger picture.
We’re watching the consolidation of the Technical Industrial Complex (TIC) into an increasingly integrated global infrastructure.
Consider what a SpaceX and Tesla combination could bring together.
AI models and computing infrastructure.
Satellite communications through Starlink.
Robotics and autonomous vehicles.
Energy generation and storage.
Space infrastructure and military communications.
Now look at China.
While Washington restricts China’s access to its most advanced AI chips, Chinese technology giants are reportedly placing enormous orders for export-compliant NVIDIA chips.
Meanwhile, Beijing is seeking to protect its own advanced AI technologies while developing its domestic computing infrastructure.
China wants access to the American technology ecosystem while building its own sovereign alternatives.
At the same time, American AI companies, chipmakers, energy providers and financial institutions are assembling enormous data-centre projects.
We’re watching the integration of:
AI
CHIPS
DATA CENTRES
ENERGY
SATELLITES
DIGITAL IDENTITY
SURVEILLANCE
MILITARY SYSTEMS
FINANCIAL INFRASTRUCTURE
This is what I mean by the emerging GLOBAL CONTROL GRID.
Not necessarily one centralised organisation controlling everything.
But increasingly interconnected regional infrastructures capable of shaping how people communicate, transact, identify themselves, access information and interact with governments.
Now add the economic layer.
As energy costs rise and the cost of capital increases, the economics of this entire ecosystem become even more important.
AI infrastructure requires extraordinary amounts of electricity, financing, land, chips and physical infrastructure.
Those costs don’t disappear.
They flow through the economy.
Households and businesses consuming energy face higher bills.
Governments and companies borrowing to finance infrastructure face higher debt-servicing costs.
Meanwhile, those issuing the loans, owning the infrastructure, refining the energy and selling the energy can capture an increasing share of the economic value.
A massive potential wealth transfer from energy consumers and borrowers to energy producers, infrastructure owners and creditors.
And much of that infrastructure is increasingly owned or financed through the same global capital markets.
Now apply my framework.
TIC builds and operates the technological infrastructure.
MIC integrates it into military, intelligence and national-security systems.
FIC finances the expansion, structures ownership and captures financial returns through debt, equity and infrastructure assets.
And as the cost of energy and capital rises, those who control scarce energy supplies and financing can gain even more leverage over those dependent on them.
The interesting part is China.
Is China building a completely separate system?
Or are we watching competing regional control grids emerge, with different governments and corporations but overlapping suppliers, capital markets and technological dependencies?
I suspect the latter.
A multipolar political world does not necessarily mean a decentralised technological world.
And the global control grid isn’t just about surveillance, AI or digital identity.
It’s also about who owns the infrastructure, who supplies the energy, who issues the debt and who ultimately pays for it.
The flags may be different.
The infrastructure may be remarkably similar.
And the wealth transfer can continue regardless of which regional power comes out ahead.
You need to be building towards the ownership layer rather than the consumption layer, every month starting today.
Boomers overwhelmingly say in polls that young people should be taxed more to pay for their social security.
Social security is going bankrupt because it is a ponzi scheme misleadingly marketed to the missionary generation as if it were some sort of retirement account, and successively marketed to each generation through the boomers this way.
Just because a ponzi scheme goes broke doesn’t make the people caught with the bag entitled to sell it to the next generation of victims.
Hold the people who created it reputationally responsible and the people who perpetuated it financially responsible.
Blame congress for spending it away.
Blame the fed for backing up the right of banks to make money out of thin air.
If boomers want to tax young people to pay for it, a fair trade would be that we
a) tank the housing market by removing its artificial support (for example Fed could sell its mortgage-backed securities)
b) subsidize home loans for everyone under 30 so they can buy them on the cheap
c) put a property tax on homes bought with subsidized loans that is used to pay boomer social security
This would be especially fair because it wouldn’t artificially tank the housing market, it would just stop artificially propping it up; only boomers who own homes would be hurt but poor boomers would be unaffected; poor boomers would even have a chance to get a home on the cheap if they had good credit; and the extra taxes would only go on young people who took advantage of the subsidy.
However, inter-generational battles are a distraction from congress, the fed, the banks, and the regulatory state.
Boomers have much more wealth than younger generations and young people can’t afford to pay their bills.
That’s not because boomers made so much better choices than young people.
It’s because money printing and public debt steals from the future.
Each generation gets worse off as the bills of the past come due on those in the future.
Boomers got houses that the government artificially made massively increase in value. Young people are now priced out of the market.
The regulatory state and subsidized college loans let boomers become university presidents making corporate CEO salaries and gave admin jobs to lower-paid boomers while the cost of education went to the moon and young people got saddled with debt.
Boomers took a blind eye to what their rulers were doing just like the missionary generation, the lost generation, the greatest generation, and the silent generation before them, and just like generation X and millennials have done after them and Z and alpha are doing so far.
Blame the spenders and the printers — congress, the fed, and the banks — not the older or younger generations.
Sue the ponzi for damages, don’t pass it on to the next sucker.
Bind together against the people who screwed us and start with the spender and the printers.
To be a bit fairer to boomers, the statement that boomers want young people to be taxed more to pay their social security benefits is derived from the dataset depicted in the attached graph.
1) The 65+ group doesn’t have their upper range defined and could include boomers, silent, and greatest generations.
2) The article about the survey itself doesn’t mention “boomers.”
3) The 55-64 group blends Gen X and boomers, so there is no actual “boomer” category.
4) The trend in support for this belief actually starts with Millenials!
The most accurate thing to say is that the older you get, the more likely you are to agree with the statement that taxes should be increased on young people to pay your own social security benefits.
A second reason to temper the interpretation is that the question is whether they agree more that young people should be protected from tax increases even if it means retirees have benefits cut, or if retirees should be protected from their benefits being cut even if it means young people pay higher taxes.
This is quite different from asking people “what is your most important political concern” and large numbers of older people saying “that we raise taxes on young people to pay for my social security.”
There are all sorts of permutations in between that would indicate different levels of commitment to the concept that taxes should be raised on young people to pay for older people’s social security, and the way the question was phrased is among the lighter forms of commitment to that concept.
Some people in the comments of my last post said this is a false binary.
It isn’t.
Social security is not an investment program.
It is by definition redistribution from young people who work to old people who no longer work.
Current taxes on workers pay for current benefits to current retirees.
The Social Security Trust Fund is bound by law not to borrow money unless authorized by Congress and this was done only once in 1982 in a loan that was repaid with interest in 1986.
Even if the law were changed to allow it to be funded with government debt, this would cause inflation that would drain the value of future dollars from young people to pay for the current dollars of older people.
All redistribution in the economy is a zero-sum or negative-sum game unless it increases productivity.
The classical definition of entrepreneurship is the intellectual and executive activity of moving resources from areas of lower productivity to areas of higher productivity.
Technology increases producticity by increasing the leverage each unit of resources has to contribute to productivity.
While entrepreneurship and technology lead to positive-sum games (the size of the pie grows), moving money from one person to another with no respect to what they do is on average a zero-sum game (the pie stays the same, some get bigger slices some get smaller slices) and moving money from workers to non-workers is a negative-sum game that actually shrinks the pie.
None of that is to say that we must maximize productivity at all costs. I am not saying that.
I am saying that social security does not increase the size of the pie so it is simply a movement of value from young people who work to older people who no longer work.
As such, the question was completely fair and the binary was not false.
There is no other way to pay for older people’s social security than to tax younger people.
The most accurate statement is that “older people support raising taxes on young people to pay for their own social security benefits, and the older they are, the more they agree.”
To be a bit fairer to boomers, the statement that boomers want young people to be taxed more to pay their social security benefits is derived from the dataset depicted in the attached graph.
1) The 65+ group doesn’t have their upper range defined and could include boomers, silent, and greatest generations.
2) The article about the survey itself doesn’t mention “boomers.”
3) The 55-64 group blends Gen X and boomers, so there is no actual “boomer” category.
4) The trend in support for this belief actually starts with Millenials!
The most accurate thing to say is that the older you get, the more likely you are to agree with the statement that taxes should be increased on young people to pay your own social security benefits.
A second reason to temper the interpretation is that the question is whether they agree more that young people should be protected from tax increases even if it means retirees have benefits cut, or if retirees should be protected from their benefits being cut even if it means young people pay higher taxes.
This is quite different from asking people “what is your most important political concern” and large numbers of older people saying “that we raise taxes on young people to pay for my social security.”
There are all sorts of permutations in between that would indicate different levels of commitment to the concept that taxes should be raised on young people to pay for older people’s social security, and the way the question was phrased is among the lighter forms of commitment to that concept.
Some people in the comments of my last post said this is a false binary.
It isn’t.
Social security is not an investment program.
It is by definition redistribution from young people who work to old people who no longer work.
Current taxes on workers pay for current benefits to current retirees.
The Social Security Trust Fund is bound by law not to borrow money unless authorized by Congress and this was done only once in 1982 in a loan that was repaid with interest in 1986.
Even if the law were changed to allow it to be funded with government debt, this would cause inflation that would drain the value of future dollars from young people to pay for the current dollars of older people.
All redistribution in the economy is a zero-sum or negative-sum game unless it increases productivity.
The classical definition of entrepreneurship is the intellectual and executive activity of moving resources from areas of lower productivity to areas of higher productivity.
Technology increases producticity by increasing the leverage each unit of resources has to contribute to productivity.
While entrepreneurship and technology lead to positive-sum games (the size of the pie grows), moving money from one person to another with no respect to what they do is on average a zero-sum game (the pie stays the same, some get bigger slices some get smaller slices) and moving money from workers to non-workers is a negative-sum game that actually shrinks the pie.
None of that is to say that we must maximize productivity at all costs. I am not saying that.
I am saying that social security does not increase the size of the pie so it is simply a movement of value from young people who work to older people who no longer work.
As such, the question was completely fair and the binary was not false.
There is no other way to pay for older people’s social security than to tax younger people.
The most accurate statement is that “older people support raising taxes on young people to pay for their own social security benefits, and the older they are, the more they agree.”
Boomers overwhelmingly say in polls that young people should be taxed more to pay for their social security.
Social security is going bankrupt because it is a ponzi scheme misleadingly marketed to the missionary generation as if it were some sort of retirement account, and successively marketed to each generation through the boomers this way.
Just because a ponzi scheme goes broke doesn’t make the people caught with the bag entitled to sell it to the next generation of victims.
Hold the people who created it reputationally responsible and the people who perpetuated it financially responsible.
Blame congress for spending it away.
Blame the fed for backing up the right of banks to make money out of thin air.
If boomers want to tax young people to pay for it, a fair trade would be that we
a) tank the housing market by removing its artificial support (for example Fed could sell its mortgage-backed securities)
b) subsidize home loans for everyone under 30 so they can buy them on the cheap
c) put a property tax on homes bought with subsidized loans that is used to pay boomer social security
This would be especially fair because it wouldn’t artificially tank the housing market, it would just stop artificially propping it up; only boomers who own homes would be hurt but poor boomers would be unaffected; poor boomers would even have a chance to get a home on the cheap if they had good credit; and the extra taxes would only go on young people who took advantage of the subsidy.
However, inter-generational battles are a distraction from congress, the fed, the banks, and the regulatory state.
Boomers have much more wealth than younger generations and young people can’t afford to pay their bills.
That’s not because boomers made so much better choices than young people.
It’s because money printing and public debt steals from the future.
Each generation gets worse off as the bills of the past come due on those in the future.
Boomers got houses that the government artificially made massively increase in value. Young people are now priced out of the market.
The regulatory state and subsidized college loans let boomers become university presidents making corporate CEO salaries and gave admin jobs to lower-paid boomers while the cost of education went to the moon and young people got saddled with debt.
Boomers took a blind eye to what their rulers were doing just like the missionary generation, the lost generation, the greatest generation, and the silent generation before them, and just like generation X and millennials have done after them and Z and alpha are doing so far.
Blame the spenders and the printers — congress, the fed, and the banks — not the older or younger generations.
Sue the ponzi for damages, don’t pass it on to the next sucker.
Bind together against the people who screwed us and start with the spender and the printers.
This is a revised version of a previous version I deleted because it came across as blaming boomers which is not what I want.
This is a revised version of a previous version I deleted because it came across as blaming boomers which is not what I want.
I take back my statement, “Boomers are the most corrupt generation.”
This was rhetorical but in a divisive direction I didn’t intend, not accurate, and not in line with what I was ultimately trying to say.
What I meant and wish to replace it with is this:
“The large disparity in wealth between boomers and younger generations is a result of corrupt policies, not spontaneous market-based rewarding of good and bad decisions.”
The problem with this quip is it appeals to our collective sense that farting is gross.
But our collective sense that pooping is gross runs much deeper.
And we all know what happens when we don’t poop…
I am not claiming here that farting and pooping have equivalent health value.
How important farting is depends on how much gas you produce. If the gas is produced, not farting it out will cause you much pain.
But on carnivore you make less gas due to less fermentable substrate.
However, simply looking at *dietary* fermentable substrate and *fartable* gas produced is misleading.
Gas produced on a carnivore diet will shift from CO2 to H2S as the fermentable substrate shifts from dietary fiber to endogenous mucins.
The fart per volume (FPV) of H2S is lower than they produced by CO2 because CO2 is an unmetabolizable end product whereas H2S is endogenously converted to soluble sulfate that leaves in the urine.
Analyzing the health implications of this requires much more careful thought than “are farts good or bad.”
Fair enough, but flying exposes you to unnatural amounts of solar irradiation and altitude stress equivalent to an average of 8500 feet (balancing pressurized cabin with actual height) for the duration of the flight, with a completely unnatural rate of going into and out of the altitude stress.
I write this on the way to the airport, but I also eat an occasional slice of pizza.
If you want to be a purist, travel by train and boat.
People think I’m crazy…
Not just for chugging honey daily, but for how I travel in general. Idk if you’ve seen the reactions to me bringing coconuts through security.. 😅
But let me say this…
When you’re on the go without preparation, this is where it’s most likely for us to get tripped up.
You’re hungry and your only options are airport McDonald’s, Starbucks, or seed oil soaked bar food… BRUTAL.
For me, I’m just not taking that risk. Why?
My health is my #1 priority.
Feeling great is my #1 priority.
Mental clarity is my #1 priority
Sleeping well is my #1 priority.
I love the work I do. I love helping people heal themselves through diet. I love educating about how to live optimally. For that, I need to be sharp every single day, no excuses.
I love surfing, being in nature, moving my body, and having endless energy. I love feeling my absolute best. Adequately fueling my body to continue doing these things. It’s a non-negotiable.
I will never sacrifice how I perform and feel for a quick treat. I mean it when I say I haven’t had a cookie or slice of pizza in over 10 years.
Let me be clear… I do understand I am on the extreme end here 😂 but I think knowledge is power, and so many people are suffering today with chronic illness, obesity, diabetes, bloating, fatigue, low energy, brain fog and bad sleep.
Being INTENTIONAL about your diet is, in my opinion, the SINGLE most powerful lever you can pull to reverse all of these things.
So call me crazy all you want, but I’ll take crazy for daily mental clarity, focus, energy, and a life lived to the fullest.
Eat like a human. This is how you thrive.
For what it’s worth, I’ve done a lot of bloodwork this year for other purposes, and I did a statistical analysis on how it’s impacted by flights.
EPO, a central marker of the hypoxia response, which governs over 200 other processes, mildly spikes after a flight for four days. By seven days, it over-recovers past its baseline then settles out.
So the altitude stress of a flight is real.
Altitude stress and its response is part of the natural human condition.
But to get to 8500 feet altitude prior to airplanes took days, making the natural way to obtain the stress very gradual.
Having reflected on this for a day, what Kennedy is saying is completely rational and not at odds with his messaging.
He’s not blaming small communities for not vaccinating against measles.
He is saying that the COVID lockdowns led to millions of missed doses of measles vaccines, which is true.
He is saying Fauci correctly predicted this would lead to measles outbreaks, which is true.
The fact that he stands for people’s right to make their own choices about vaccination does not mean that vaccination rates don’t influence prevalence of an infectious disease. They do.
The fact that Fauci is corrupt and belongs behind bars doesn’t mean everything he ever said is wrong. It isn’t.
Kennedy is essentially disclaiming blame put on him, his HHS, Trump, the Amish, and anyone who chose not to vaccinate and saying that the COVID lockdowns made this inevitable and even their great advocate, Fauci, said so himself.
Withholding tax and government borrowing are the two greatest scams in American government history.
Withholding tax: you don't see it, so you feel like your employer isn't paying it to you, then the government gives you a "refund" and you feel like the government gave you free money when actually it took half of it.
Government borrowing is THE major driver of your prices going up.
A market without government borrowing produces ever-lower prices from technological advancements that produce more goods and services with less inputs, thereby making them more available and more affordable to you.
Government borrowing not only makes your prices go up and your dollar worth less but also pushes interest rates up.
The worst scammers tell you they gave you "tax cuts" when they financed it with deficit spending. They were taking your money by path A, and they shifted to doubling the money they would take by path B then gave you back the money they took from path A and you again felt like they "gave you money," when they just doubled how much they were taking.
The reality is government market manipulation can *only* lead to a zero-sum game so if the government pushes some interest rates down, others will go up, when growth and inflation expectations are held constant.
For example, Bessent is trying to make the government debt less expensive to roll over for the government.
One thing he has been doing is buying back long-dated bonds. More recently he discussed not issuing the long-dated bonds.
Today inflation came out hot, so interest rates went up.
But look at the spread:
2-year bonds up a lot, 20- and 30-year bonds up barely, 10-year in the middle.
That reflects Bessent's manipulation of the long-dated bond supply to push long-dated government debt prices lower.
But what does 2s and 10s popping mean for you?
The 2-year is highly correlated with credit card rates because it reflects in large part investor expectations for what the Fed is going to do with the Fed Funds rate, and credit card companies derive their average rates from the Fed Funds rate.
The 10-year is a direct driver of mortgage rates.
So borrowing cheaper for government, more expensive for homeowners, and a lot more expensive for people with credit card debt.
So, big punish for the poor people who don't understand finances or feel overwhelmed by costs, little smack to the conservative traditional responsible savers who own homes and refinance mortgages.
There should be a law that an open-source python program that can be vetted by stakeholders and experts of all types be used to compute the amount of money taken from you by government spending that is given back to you as an official report on what was taken from you.
Update: after digesting the inflation news the bond market calmed down.
But the trend is the same: the Bessent maneuver has the 2y up, long down, 10s in the middle.
The point is the government can’t paper up the destruction of your living standard caused by deficit spending.
It can just play whack-a-mole and let the hurt pop out somewhere else.
If it whacks down its own 30-year bonds, 2s pop and people living off credit card debt wind up more screwed than they already are.
If Kennedy can’t stop CDC from publishing this one piece of nonsense above all pieces of nonsense he has zero power and there is just no point in MAHA. It’s dead.
