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The Defense Circuits Lab studies the neuronal basis for aversive emotional states, such as fear and anxiety

Würzburg, Germany
Joined May 2019
Photo by DefenseCircuitsLab (@CircuitsLab)Photo by DefenseCircuitsLab (@CircuitsLab)Photo by DefenseCircuitsLab (@CircuitsLab)Photo by DefenseCircuitsLab (@CircuitsLab)Photo by DefenseCircuitsLab (@CircuitsLab)Photo by DefenseCircuitsLab (@CircuitsLab)Photo by DefenseCircuitsLab (@CircuitsLab)Photo by DefenseCircuitsLab (@CircuitsLab)Photo by DefenseCircuitsLab (@CircuitsLab)Photo by DefenseCircuitsLab (@CircuitsLab)
Get to know the RTG 2660 🥳youtu.be/zO2d8fcB8rk?feature…
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🎉Join the RTG! We have 13 PhD positions available in our translational Research Training Group 2660 on approach and avoidance behaviour👀
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DefenseCircuitsLab retweeted
A few months ago @KarlDeisseroth & team achieved a huge milestone in the cardiac opto & interoception fields! I enjoyed highlighting this great work at @sigtrans_sttt with @CircuitsLab & @StefanFrantz @Uniklinikum_Wue Exciting times for 🫀/🧠 research! nature.com/articles/s41392-0…
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DefenseCircuitsLab retweeted
📢 CEN is hiring an early career researcher for 20 months at @CircuitsLab @Uni_WUE The project studies cerebellar neural circuits during emotional states in mouse models. #Neuroscience 🧠🐁 #SpreadTheWord  #JoinUs @MSCActions Apply by the 30th July 👉cen-itn.net/job-offers/
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Yesterday we had the honor to welcome Prof. Valery Grinevich & Dr. Eduard Maier from @zi_mannheim at our Dinner Meeting. They gave an exciting talk on "Operating Principles of the Brain Oxytocin System" & "Behavioral & Neural Correlates of Play-Associated Habituation". 🐁
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DefenseCircuitsLab retweeted
Think animal research is essential in biology/medicine? Then say so! Following a massive citizens initiative, European Parliament is about to discuss a complete ban. This is real. Please support our pledge: braincouncil.eu/pledge-for-s…
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DefenseCircuitsLab retweeted
#GabrielaNeubertdaSilva aims to understand the precise anatomical connections between cerebellum and brainstem defense circuitry and their functional role in fear and anxiety. She gets this information by combining viral tracing strategies with optogenetics in mice @CircuitsLab
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The cerebellum regulates fear extinction through thalamo-prefrontal cortex interactions in male mice ift.tt/sVDH0ZG
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DefenseCircuitsLab retweeted
@vassiliemma at @UoBrisPPN investigates how the cerebellum controls affective behaviour. She is interested in individual differences in emotional states and how this changes during chronic pain. @BristolNeurosci
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DefenseCircuitsLab retweeted
@ahsanayyaz42 studies the neurophysiological processes performed by the cerebellum, thalamus and prefrontal cortex during fear learning in mice and how manipulating this brain substructure with optogenetic techniques modifies emotional behaviour. @NBC_ParisENS #BrainWeek
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DefenseCircuitsLab retweeted
And here's a full 1min40sec version of me explaining our new findings on🫀 -⏳ -🧠. Stay tuned! sciencedirect.com/science/ar…
Can hearts distort observation of time? A report by @RHULPsychology @RoyalHolloway investigates how our heartbeats can distort our perception of time. Listen to @irena_arslanova explain how it all works bit.ly/3Fdu5Xk and read more here bit.ly/3ZU3DKe
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DefenseCircuitsLab retweeted
#NinaSeiffert at @Uni_WUE uses deep-brain imaging technology to monitor the activity of specific brain cell types within the cerebellum and brainstem of mice. She wants to better understand the cerebellar circuit dynamics underlying defensive emotional states. @CircuitsLab
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DefenseCircuitsLab retweeted
📢#BrainAwarenessWeek is finally happening.🧠🎉 This week, we will share our contribution to neuroscience, its importance for improving people's lives and, hopefully, inspire new neuroscientists. Join @CEN_ITN on this tour! @dana_fdn
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DefenseCircuitsLab retweeted
Cerebellum & Emotional Networks is a @MSCActions Innovative Training Network exploring the brain circuits that underlie emotional behaviour. Through a virtual institute of 8 EU universities and 9 partners, we provide training for 15 PhD students. 👉 cen-itn.net/
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DefenseCircuitsLab retweeted
While some postdocs go out for beers on Friday nights, Alexander Dieter and @Andrey_Formozov played around with optical fibers. The result is Fused Fiber Photometry: a cheap and highly versatile photometry system built around a fused fiber coupler. Cheers! cell.com/cell-reports-method…
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Was passiert im Gehirn, wenn wir Angst haben? Das @CircuitsLab @uniklinikum_wue hat Rahmenkonzept erstellt, um Ausprägung von Verhalten & körperl. Anpassungen inkl. komplexer Dynamik zu charakterisieren & so Gehirnaktivität bei Angst besser zu verstehen. idwf.de/-DF3wAC
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DefenseCircuitsLab retweeted
Anxiety can be created by the body, mouse heart study suggests go.nature.com/3YbYZWN
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DefenseCircuitsLab retweeted
As a resident I was intrigued by stats linking panic with cardiac disorders (mitral prolapse/tachycardia). 20 yrs later we finally could explore this! (w/ @HsuehBrian @ritchie_chen). William James on the right track: “we feel...afraid because we tremble”. rdcu.be/c6Fro
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DefenseCircuitsLab retweeted
We’re excited to extend noninvasive optogenetics beyond the brain to address a nearly 150-year-old question in a new study out today @Nature: nature.com/articles/s41586-0… Work led by @HsuehBrian, myself, and @KarlDeisseroth, with an amazing team in the D-lab and many others!
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DefenseCircuitsLab retweeted
Congrats to Dr. Annemarie Schulte for the successful public defense of her PhD thesis "In vitro reprogramming of glial cells from adult spinal ganglia into nociceptor-like neurons". Her work provides a valuable contribution to the Z project of ResolvePAIN.
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