Dad | Husband | Aging, Diabetes and Exercise Researcher | Liverpool FC | Weekend Warrior
Orlando, FL by way of Dublin, Ireland
Joined March 2009
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Sharing the result of a collaboration with @kistanford6 @woldloren and team @OhioStateDHLRI: The brown fat–derived lipokine 12,13-diHOME combats age-related heart decline by inhibiting CaMKII and reducing ER stress.
doi.org/10.1038/s41467-025-6…
@AdventHealthMD
Paul Coen retweeted
Sharing our paper - incretin receptors in peripheral nervous system. Much work w these signals centered on functions in brain only, but clearly also neural actions in PNS. We show staining on human nerves. Great work by @sousaerica90 in our lab #incretins tinyurl.com/5n6e99wy
The Study of Muscle Mobility and Aging (SOMMA) is open for enrollment!!
SOMMA is a longitudinal cohort study designed to examine the biological properties of skeletal muscle that predict onset of disability or dementia in older adults.
sommaonline.ucsf.edu
Delighted to share a recent publication from a long standing collaboration with @SiobhanMalany, Maddalena Parafati, and their outstanding team at University of Florida.
cell.com/stem-cell-reports/f…
@SpaceX
@stemcellreports
@AdventHealthMD
Paul Coen retweeted
Just a reminder as to the mechanism of action of Bimagrumab, and it's origins ;-).
An Antibody Blocking Activin Type II Receptors Induces Strong Skeletal Muscle Hypertrophy and Protects from Atrophy.
pmc.ncbi.nlm.nih.gov/article…
Paul Coen retweeted
We welcome Dr. Jim Carson, the new Director of the Texas A&M Huffines Institute for Sports Medicine & Human Performance, to San Antonio for our Molecular Metabolism Seminar Series.
New pub from Atalie Thompson and the team at Wake Forest University SOM.
academic.oup.com/biomedgeron…
We are recruiting! We have an open position for a Postdoctoral Fellow with the Aging, Exercise and Bioenergetics group at the Translational Research Institute in Orlando, Florida. If you know of an any trainees who might be interested, please let them know!
WTF! Leadership of the National Institute on Aging was apparently “decimated,” with deputy director Amy Kelly and scientific director Luigi Ferrucci— “one of the brightest luminaries in the world in gerontology,” per a source — among those fired.
splinter.com/bloodbath-at-ni…
Congrats @MattStockPhD ! Great study!!
PUBLISHED in @japplphysiol! Working with @DrMikeRoberts and co, we investigated atrophic, hypertrophic, and molecular adaptations associated with 2 wks of immobilization followed by 8 wks of resistance training, comparing the results between trained vs untrained participants.
Paul Coen retweeted
The Global Consensus on #HealthyLongevity emphasizes:
🌟 Movement is the key to a healthy life! 🌟
Scientific evidence shows that staying physically active, maintaining a healthy diet, avoiding smoking, and limiting alcohol consumption are essential for well-being at any age.
🔴 Left side: The pathway of inactivity: higher risk of diseases, loss of muscle mass, and decreased functional capacity.
🟢 Right side: Physical activity as preventive medicine: preserves physiological functions and lowers the risk of falls, fractures, and mortality.
💡 Remember! While aging is inevitable, exercise slows down the process and enhances your quality of life. Choose to move, choose to live better!
🔗 Learn more: sciencedirect.com/science/ar…
#ExerciseIsMedicine #HealthyAging #ActiveLifestyle #ICFSR #PhysicalActivity #Longevity #PreventionIsKey #StrengthAndVitality #HealthyHabits #StayActive
Delighted to share a recent consensus statement on the integration of PA into health promotion, disease prevention, and management strategies for older adults. This is a very comprehensive set of guidelines and rationale. Enjoy!
🧵 The Ultimate Guide to Healthy Longevity Through Exercise for Older Adults!
A NEW global consensus is here, led by @ICFSR2025 @JNHA6 experts! 🎉
💡 Discover evidence-based recommendations to enhance life quality & health span in aging populations. Let’s dive in!👇 #LongevityScience
Free download: sciencedirect.com/science/ar…
Paul Coen retweeted
Come join us in Columbus in February!! @OhioStateDHLRI @OSUWexMed
It’s time! Early registration @ Ohio State: Thurs Feb 20 PHAT/TRINS (adipose & NeuroMetabolism; Scherer keynote), then Fri Feb 21 @BigTenAcademic BTAA Lipids meeting! Register here: cvent.me/x03aAX Programs posted here & Cvent soon: ktownsendlab.com/townsend-la… @kistanford6
An important perspective and counter to the question posed by Conte, Hall and Klein; "Is Weight Loss-Induced Muscle Mass Loss Clinically Relevant?"
jamanetwork.com/journals/jam…
More work needs to be done in this area!
Muscle matters: the effects of medically induced weight loss on skeletal muscle thelancet.com/journals/landi…
A big thanks to @m_roves for leading this effort!!
Great collaboration with international experts @stelar75 @CoenPM @OroborosI in #humanskeletalmucle #mitochondriarespiration #bioenergetics
Partly supported for COST action 1523 MitoEAGLE. Relevant methodological aspects to take into account.
sciencedirect.com/science/ar…
Paul Coen retweeted
The Department of Cellular & Integrative Physiology at UT Health San Antonio is recruiting for a Physiology faculty tenure track position.
uthscsa.referrals.selectmind…
Great talk @HeWaHippo! I learned a lot about the importance of glucose on tissue growth (cancer and healthy tissue growth)
Great honour to present our ideas on the biochemistry of muscle hypertrophy at @BiochemExercise at @UL in front of many exercise physiology legends!🍀🍀🍀