@ColecraftL

Tweets are from lab members.

Joined May 2022
  • Tweets7
  • Following45
  • Followers97
Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies biorxiv.org/content/10.1101/…

Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies

Targeted recruitment of E3 ubiquitin ligases to degrade traditionally undruggable proteins is a disruptive paradigm for developing new therapeutics. Two salient limitations are that <2% of the ~600...

biorxiv.org
1
6
1
27
3,542
Colecraft Lab retweeted
bioRxiv@biorxivpreprint31 May 2024
Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies biorxiv.org/cgi/content/shor… #bioRxiv
1
6
4,634
Colecraft Lab retweeted
Norbert Weiss@TheWeissLab14 Nov 2022
In this chapter, Sergej Borowik & Henry M. Colecraft @ColumbiaMed provide a comprehensive overview of the role of the Cavβ subunit in the regulation of #calcium #ionchannels, its pathophysiological implication, and its potential as therapeutic target ➡️ bit.ly/3WZMmi4
4
14
Happy to share our latest work published in @NatureComms. Thanks to collaborators @ElectrosomeUCSF and Roger A. Bannister. @ColumbiaPHY @ColumbiaMed Selective posttranslational inhibition of CaVβ1-associated voltage-dependent calcium channels with a… disq.us/t/4cu0kl6
2
10
Twitter opener from the @HColecraft lab @ColumbiaPHY #Firsttweet
1
2
Targeted ubiquitination of sensory neuron calcium channels reduces the development of neuropathic pain pnas.org/doi/10.1073/pnas.21…

Targeted ubiquitination of sensory neuron calcium channels reduces the development of neuropathic...

Neuropathic pain caused by lesions to somatosensory neurons due to injury or disease is a widespread public health problem that is inadequately man...

pnas.org
1
4
Load more