Professor at UVic. interested in neuroscience, micro-circulation, hockey. Lab website: https://xitter.cf/t.co/mYMRXqmTMS
Victoria, British Columbia
Joined January 2018
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Pleased to share our latest (now published), from star student Kamal Narayana. Lowering (not increasing) peri-infarct blood flow beyond 24h period, improved #stroke recovery by lessening blood brain barrier disruption and #neuroinflammation.
See paper at:
nature.com/articles/s41419-0…
New finding from the lab. This surprised us since it went against the common assumption that increasing peri-infarct blood flow is best for stroke recovery. Congrats to Kamal and the team!
biorxiv.org/content/10.1101/…
peterattiamd.com/link
Nice write up on our paper by @PeterAttiaMD
Was a pleasure to contribute a little to this new work from Tuan Trang and Yuta Kohro
molecularbrain.biomedcentral…
Happy to share new paper from MSc grads Myrthe and Jenna. We asked the question, when part of the brain dies during stroke, what happens to local and distant cortical neurons that innervate the stroke site (in S1 cortex) or those that receive outputs?
journals.sagepub.com/doi/10.…
The pathobiology of neurovascular aging: Neuron cell.com/neuron/abstract/S08…
Craig E Brown retweeted
Endothelial Response to Blood-Brain Barrier Disruption in the Human Brain | JCI Insight
insight.jci.org/articles/vie…
Craig E Brown retweeted
Happy to share our study on the beneficial role of the innate immune system on vascular remodeling in retinal disease and potential negative impact of steroids. @MasayukiHata7 @UMontreal @ARVOinfo @CIHR_IRSC @_BrightFocus @AmDiabetesAssn @iserworld
pnas.org/doi/10.1073/pnas.24…
Craig E Brown retweeted
That Trudeau would expect @cafreeland to deliver the FES after telling her ON FRIDAY he was firing her is peak chauvinistic arrogance. Wtf did he think she was going to do? LOL
Then he sat around all weekend and released a vid of him baking buns.
IDIOT
Craig E Brown retweeted
iFlpMosaics are now published @naturemethods. A compendium of novel genetic tools and related methods for inducing and analysing genetic mosaics in a high-throughput manner. nature.com/articles/s41592-0… Tweetorial 👇
Craig E Brown retweeted
Excited to share our work, new in @ScienceMagazine: science.org/doi/10.1126/scie…. We explored how sex chromosomes, gonadal hormones, and their interaction shape cellular responses in aging and #Alzheimers mouse models. This led to key insights on Tlr7 and neurodegeneration 🧵(1/5)
@westjet screwed us on our Europe trip. Of course no one is surprised by this. Canadians have few travel options and are forced to put up with this crap. Its especially bad for small city travellers that always have to make a connection
vancouver.citynews.ca/2023/0…
Happy update. In response to losing a day of holiday and 1 night hotel in Paris, @WestJet offered us a $15 food voucher. They really do care!!
Craig E Brown retweeted
The epidemiology of type 1 diabetes mellitus in older adults go.nature.com/4hR0q8e #diabetes #T1DM #T1D
Congrats to the team! Here we directly image and quantify cerebral #angiogenesis and pruning in vivo. Found interesting regional differences and dependence on #notch signalling. Where you look does matter! cell.com/cell-reports/fullte…
Craig E Brown retweeted
Excited to share our new work out in @Nature !
Learning-Associated Astrocyte Ensembles Regulate Memory Recall
nature.com/articles/s41586-0…
Pleased to share our new paper implicating #interleukin 10 in perturbed #brain #microcirculation and #cognitiveimpairment in mouse model of type 1 diabetes. Congrats to the team @uvic, @sharmasorabh88, @UVicMedSciences, @NatMetabolism, nature.com/articles/s42255-0…
Craig E Brown retweeted
In diabetes, the capillary microvessels can become obstructed, leading to damage to neurons and cognitive deficits. A new mechanism elucidated involving interleukin-10 may help explain why
@NatMetabolism
nature.com/articles/s42255-0…
@CraigEdBrown @MyUVic
nature.com/articles/s42255-0…
@celineriera
