Redefining digestive health by pioneering non-endoscopic diagnostics, enabling early detection of diseases and access to care for everyone, everywhere.

Cambridge, England
Joined June 2020
Our EndoSign® cell collection device has received 510(k) clearance from the FDA, enabling earlier and more efficient detection of esophageal pre-cancer and other conditions. #DetectToProtect #FDA
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Persistent #reflux shouldn't be ignored. @HeartburnCancer UK's blog highlights Jess’s Rule, encouraging GPs to review patients presenting three times with the same symptoms. Earlier investigation can make a difference: Discover EndoSign® for #heartburn: heartburncanceruk.org/blog/w…
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Replying to @CytedHealth
@CytedHealth’s EndoSign detects Barrett’s esophagus with 90% sensitivity in US study pharmadevicenews.com/cyted-h… EndoSign achieved 90% sensitivity and 86% specificity for Barrett's esophagus in a prospective 324-participant US study, with successful cell collection in 95% of patients. Cyted Health also reported 100% sensitivity for dysplasia and esophageal cancer, but positive results still require endoscopy and the molecular test itself is not FDA-cleared. #CytedHealth #EndoSign #DETECTME #BarrettsEsophagus #EsophagealCancer #MolecularDiagnostics #EarlyDetection #MedicalDevices #Gastroenterology #ACG2026
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Changes to #FIT criteria are expected to increase NHS #endoscopy activity by 35 %. With services already under pressure, effective triage is more important than ever. Read how EndoSign® can help protect capacity: endosign.com/post/how-can-en…
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We’re pleased to welcome Thomas A. West as Board Chair and Epstein, Robert as Non-Executive Director at Cyted. Their combined expertise will be invaluable as we continue to bring earlier, more accurate detection of esophageal disease to more patients. cytedhealth.com/uk/post/cyte…
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What support is available to help teams deliver EndoSign® in the NHS? We provide training and ongoing support, with a cascade training model to help build sustainable local expertise. Learn more: endosign.com/hcp/endosign-in… #EndoSign #Gastroenterology #NHS
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20 % of the UK population experiences GORD, yet serious pathology is rare. How can services identify high-risk patients without overwhelming endoscopy pathways? Read our article that explores risk stratification with EndoSign®: gastroenterologytoday.com/vi… #GORD #EndoSign
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Many #NHS services are moving beyond endoscopy-first approaches with risk stratification, nurse-led assessment and less invasive investigations with EndoSign®. How has your pathway evolved? endosign.com/
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How do patients respond to EndoSign? A study with EndoSign® reported a 95.3 % swallow success rate and no adverse complications. Read the study from @gastroendonews : gastroendonews.com/PRN/Artic…
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Eddie lived with heartburn for 40+ years, unaware it could lead to cancer. One capsule sponge test detected early cell changes, leading to treatment before the disease could progress. Read his story: youtube.com/watch?v=4ICuevA9… #Reflux #EndoSign #OesophagealCancer
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Not every Barrett's oesophagus patient carries the same cancer risk. So, should everyone follow the same surveillance pathway? Read our article in @thenhenews that discusses how biomarker-based risk stratification can support more targeted care: nationalhealthexecutive.com/…
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A UK study found sponge-based surveillance detected more high-grade dysplasia or adenocarcinoma than endoscopy. A second study with EndoSign® reported a 95.3 % swallow success rate and no adverse complications. Read more in @gastroendonews: gastroendonews.com/PRN/Artic…
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Clinicians are being urged to reduce low yield endoscopies, and earlier risk stratification could be key to this. EndoSign® capsule sponge testing offers minimally invasive triage to support targeted referral. Learn more: endosign.com #Endoscopy #BarrettsOesophagus
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What is the difference between capsule endoscopy and capsule sponge technology? Explore more of our frequently asked questions: #UpperGI #Diagnostics #OesophagealCancer #Reflux #Endoscopy
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31-MarYou may know EndoSign® as the ‘pill on a string’ – but what is it? A minimally invasive triage tool that collects oesophageal cells to assess #reflux and Barrett’s risk. Learn more: endosign.com #OesophagealCancer #Reflux
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Oesophageal cancer is often diagnosed late, impacting outcomes. 5 year survival can be ~95 % when detected early, but reduces to 5-40 % at advanced stages. EndoSign® enables minimally invasive risk stratification for targeted referrals. Learn more: endosign.com
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Up to 75 % of UK #gastroscopies may be performed in patients with <1 % cancer risk. Earlier risk stratification could reduce low yield procedures. EndoSign® supports minimally invasive assessment to better target #endoscopy. Learn more: endosign.com
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What do patients think of EndoSign® capsule sponge test? Read more about the patient experience here: #HeartburnHealthCheck #OesophagealCancer #EarlyDiagnosis #NHSInnovation
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💭 What does long-term follow-up 📊 on low-risk patients w/ Barrett's esophagus triaged with 🧽 capsule sponge look like❓ ✅ Check out these interesting and reassuring results from a study (relatively small sample size) @FrontGastro_BMJ 🖇️ bit.ly/4moRYQ1 that showed ↪️ No significant differences in the detection of dysplasia or cancer in patients with follow-up endoscopy vs repeat capsule sponge testing and endoscopy ↪️ All cases w/ HGD and cancer were detected by repeat capsule sponge testing w/ positive biomarkers (atypia and p53) 👏 Thank you to authors @siobhan_chien @GastronautIan Paul Glen Gavin Bryce Michael Miller Neil Cruickshank Andrew Crumley Jonathan Fletcher Ivan Gunjaca Perminder Phull @JKApollos Kevin Robertson Grant M Fullarton @PhilSmithIsBack @OTavabie @dr_aditi_kumar @TrevorTabone @eathar_s @IrenePerezMD @KGananandan @zare_benjamin @medicalreg @dtleiberman @BASLedu @BSGtrainees @ulstergastro #GITwitter
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1 in 100 people in the UK may require surveillance for Barrett’s oesophagus, creating sustained #endoscopy demand. EndoSign® provides minimally invasive risk stratification, helping prioritise those most likely to benefit from endoscopy. Learn more: endosign.com
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