We study the biology of normal B cells & their cancerous counterparts. Affiliated with @IcahnMountSinai @TischCancer @SinaiImmunol.
Joined June 2020
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The Dominguez-Sola Lab retweeted
Every child deserves the chance to survive and thrive. ✨
In honor of National Cancer Survivor Day, support lifesaving childhood cancer research if you believe in our mission: ow.ly/qiH450Z6lWQ
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#cancersurvivor #togetherforthe5th
I think that the beauty (if I may) of this study is on the cell models that we built with @PapapetrouMDPhD. These are based on previous work in her lab exphem.org/article/S0301-472… and extremely valuable, it turns out, to understand how MYC works to transform cells.
What happens when MYC signaling is sustained in hematopoietic cells? This study from @PapapetrouMDPhD and @DDSoLab examines how persistent MYC activity blocks differentiation and promotes leukemic transformation. Explore on exphem.org/article/S0301-472…
More posts to follow here and on Bluesky, where we just started an account in case you’re interested.
This is the latest work from the lab, in collaboration with Peter Heeger at @CedarsSinai. We had the precious help of many, including @FribourgLab, Alex Tsankov’s lab and @pardi_lab. You can find it at @JExpMed:
rupress.org/jem/article-abst…
The Dominguez-Sola Lab retweeted
What happens when MYC signaling is sustained in hematopoietic cells? This study from @PapapetrouMDPhD and @DDSoLab examines how persistent MYC activity blocks differentiation and promotes leukemic transformation. Explore on exphem.org/article/S0301-472…
The Dominguez-Sola Lab retweeted
Congrats to David (@DDSoLab), Eirini (@PapapetrouMDPhD), and the team on how persistent MYC rewires epigenetic landscapes and TF networks, revealing sustained deregulation drives MYC-driven leukemic transformation. @ISEHSociety
The Dominguez-Sola Lab retweeted
Over 600 New Yorkers attended our Virtual Town Hall today to advocate for state-based science funding! We were joined by researchers, patients, institutions, and elected officials.
Support a New York State Biomedical Institute for a Healthier, More Affordable Future - Sign the Petition! c.org/YZj6QQZshL via @Change
For those who were not aware of this initiative:
c.org/jv6GfQwrjg
We are extremely grateful to @StBaldrick especially to Jack's Pack @jackspack10 ,(stbaldricks.org/hero-funds/j…), for their support in our quest to find better treatments for Burkitt Lymphoma.
Your donation dollars are turning hope into work that saves lives. 💚 Nearly $1.2 million in new grants just announced, and you can learn more about what you helped make possible: bit.ly/48b2cwJ
The Dominguez-Sola Lab retweeted
Dominguez-Sola @DDSoLab highlights work by Yada et al. (bit.ly/46Quz1c) which demonstrates that effective antibody affinity selection in germinal centers relies on the store-operated calcium entry component of the B cell receptor signaling network bit.ly/3Ndxmdd
