Director of the Neuroimaging Laboratory @stjuderesearch. Opinions my own.
Memphis
Joined March 2009
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Daniel Stabley retweeted
Hey y'all, I'd like networking reposts if you can. Georgios Skiniotis and I are pleased to announce a unique faculty position at St. Jude, and we're both particularly excited about what this search could become.
It is a true joint strategic effort between the Center of Excellence for Structural Cell Biology and the Division of Neuronal Cell Biology in the Department of Developmental Neurobiology.
The CoE-SCB is an intellectual community of investigators developing and applying emerging structural and cellular imaging approaches to understand biological mechanisms directly within cells and tissues.
The Division of Neuronal Cell Biology and Department of Developmental Neurobiology bring a complementary culture centered on fundamental questions of neuronal development, organization, and function, with deep expertise in advanced cellular imaging.
We are looking for the rare scientist who pursues important questions in neuronal cell biology wherever they lead and brings advanced structural and cellular imaging to bear.
If the intersection between cryo-ET or vEM and neuronal cell biology feels like your scientific home, take a look.
Application link to follow in the post belowš
Daniel Stabley retweeted
Researchers showed that brain cells respond differently to the H3.3 K27M mutation depending on their location in the developing brain. The findings help explain why diffuse midline glioma (DMG) develops where it does and identify potential therapeutic targets. bit.ly/4y3AHka
Daniel Stabley retweeted
Hey yāall š I need a little repost magic. š„
The Solecki lab is recruiting MULTIPLE postdocs for a chromatin imaging project at St. Jude.
This work sits at the intersection of live-cell imaging, neuronal cell biology, chromatin regulation, and quantitative image analysis ā and the eye-popping video below shows exactly why itās so exciting.
This may be for you if you are:
ā¢ A neurobiologist who wants to become DANGEROUS in cell biology š§
ā¢ A chromatin biologist who wants to ditch endpoint molecular biology and actually watch nuclear states unfold in living cells š§¬
ā¢ An imaging scientist or biophysicist who wants to get messy in real cells, not idealized samples š¬
A quantitative mindset is required. Prior experience in every area is not.
If you ever imagined touring the nucleus like nuclear render and our Pol II biosensor belowā¦ reach out because WE can do it.
Tag a scientist who needs to see this + RT to help us find them! š Letās make chromatin biology history.
Daniel Stabley retweeted
Most of what we āseeā in 3D #microscopy is wrong. But a new preprint from the lab driven by Anna Pittman comes to the rescue.
Hard truth: humans are bad at seeing 3D on screens. We collapse volumes, look at image slices and pretend itās enough. But, a model can interrogate the full 3D structure. Rather than work with black box , Anna rebuilt a classic (bag-of-visual-words) for 3D: with decisions you can actually understand. A huge win for interpretability and we use that power to dissect neuronal chromatin organization š
Sheās on the data scientist job market! Donāt miss her! Let's get some reposts to get her some exposure.
Daniel Stabley retweeted
1/ Better late than never, hereās a long thread of threads summarizing our MOSAIC preprint.
If youāre curious about the process by which a new microscope is conceived and brought into the world, this is the thread for you. If youāve come for eye candy, thereās plenty of that too below.
biorxiv.org/content/10.1101/ā¦
Daniel Stabley retweeted
Finally here! Our preprint on the MOSAIC, a multimodal adaptive optical microscope enabling nonāinvasive ināvivo imaging from molecules to organisms, is out.
biorxiv.org/content/10.1101/ā¦
@Eric_Betzig @legant_lab
Daniel Stabley retweeted
The MOSAIC reconfigurable microscope by @Eric_Betzig et al is finally out!
MOSAIC integrates multiple advanced imaging techniques including light-sheet, label-free, super-resolution, and multi-photon, all equipped with adaptive optics:
biorxiv.org/content/10.1101/ā¦
Daniel Stabley retweeted
Today has been AMAZING! Shoutout to all of you incredible humans who experienced the @StJude campus today! We are so grateful for you being here!
Why is it always "vibe coded this game with Claude in an hour" and not "vibe coded this re-write of SIM reconstruction in an hour so an entire field isn't dependent on CUDA code from 10 years ago".
Daniel Stabley retweeted
Beyond excited to share my big @StJude news! Weāre going to build an amazing hub for imaging technology development and deployment - driven by St Judeās mission to transform the way the world understands and treats pediatric catastrophic diseases. Imaging innovators come join us!
St. Jude welcomes @HillmanLab as the founding chair of the new Department of Imaging Sciences. Her team will develop innovative tools to accelerate discovery and improve patient care. ow.ly/GZQG50UL653
Daniel Stabley retweeted
Please RT!
We are very proud to announce LSFM 2025!Ā The light-sheet conference/workshop will be held this year June 1st-7th, 2025, at the Mount Desert Island Biological Laboratory (MDIBL) @MDIBL in Bar Harbor, Maine.
Application portal open now!
Application deadline (rolling) May 12th, 2025.
Limited financial assistance is available.
mdibl.org/course/lsfm-2025/
This is the only comprehensive conference/workshop of this length in the US.
This year, the conference will be 1.5 days and the workshop will be 4 days (more time on the systems!).
Workshop space is limited. First come!
Confirmed Speakers;
Reto Fiolka @RetoPaul - UTSW - Keynote
Steve Ross @NikonInst -Nikon Instruments
Simon Watkins @simoncwatkins1 -University of Pittsburgh
Claudette St. Croix @ClaudetteCroix -University of Pittsburgh
Kate McDole - MRC Laboratory of Molecular Biology
Holly Gibbs @holly_c_gibbs -Texas A&M
Anna-Karin Gustavsson @gustavssonlab -Rice University
Stephanie Kramer - Case Western Reserve University
Ruixuan Gao @Ruixuan3 -University of Illinois, Chicago
Bingying Chen @bingy_C -UTSW
Fabian Voight @voigtvision -Harvard University
Stephanie Rudolph @StephRudolphLab - Albert Einstein College of Medicine
Melissa Cooper @MelCooperPhD -NYU Langone Health
Doug Shepard @DougPShepherd -Arizona State Univesity
Doug Richardson @Harvard_CBI -Harvard University
Emmanuel Reynaud @ReynaudEmmanuel -University College Dublin
Kara Cerveny @kara_cerveny -Reed College
Carsten Wolff @carsten_wolff -MBL
With more to come!
Confirmed vendors:Ā 12 systems!
3i
ASI
Leica
Bruker
MBF
Zeiss
Miltenyi
LifeCanvas
LIT
Hamamatsu
Abhishek Kumar (co-organizer) - MBL
Kate McDole (co-organizer) - MRC Laboratory of Molecular Biology
Gary Laevsky (co-organizer) - Princeton University
Path-traced render of the nucleus of a 16x expanded 3T3 cell stained for total DNA as imaged via Lattice Light Sheet #Microscopy for #FluorescenceFriday.
It's #FluorescenceFriday, so here's a Lattice Light Sheet volume of some 3T3 cells (labeled: microtubules and DNA) from one of our in-house built microscopes. Rendered with @AllenInstitute Agave.
