Cellular and Molecular #Bioengineering laboratory at #UMN. Applying #MathematicalModeling #Microscopy and #Microsystems to understand and treat #Cancer.

Minnesota, USA
Joined March 2015
Happening now: David Odde, PhD (@DavidOddeLab) shares new insights on how cells migrate and how tumors grow, particularly in brain cancer progression. Key takeaways: • Classic collision theory sets an upper limit for immune cell effectiveness. • T cell migration is predicted to be potentiated by increasing myosin contractility. • CA-Rho OE potentiates myosin activity, T cell migration, and suppresses tumors better than. • We are seeking to initiate a clinical trial for CA-Rho CAR-T cell therapy. #NAMsSymposium
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David Odde Lab retweeted
✅ Check out the latest from @matilla_roberto @DavidOddeLab in @CellReports! “Biophysical modeling identifies an optimal hybrid amoeboid-mesenchymal mechanism for maximal T cell migration speeds” sciencedirect.com/science/ar…
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David Odde Lab retweeted
🇮🇷 We WILL win And We will make Iran great again And we won’t forget who helped us when we needed @realDonaldTrump @LindseyGrahamSC @elonmusk @BillAckman @TomCottonAR @wolfejosh @JTLonsdale
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David Odde Lab retweeted
URGENT call to help #Iran immediately🚨 Based on my conversations with doctors in Tehran, Fars, Isfahan, Lorestan, Rasht, Sari & Kerman, as well as reports, photos & footages from eyewitnesses, the estimated death toll of protestors exceeds 5,000. #DigitalBlackoutIran #R2P
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David Odde Lab retweeted
What a cursed silence. The footage comes from a place that is neither a hospital nor a morgue. Hospitals and morgues are overwhelmed, and families are forced to search for their loved ones in temporary, unknown locations. What is happening in Iran right now is an unprecedented humanitarian catastrophe. Reports and videos from the ground show ordinary people being killed in massive numbers scenes that the world can no longer ignore. This is no longer mere repression; it is an organized massacre unfolding in real time before the eyes of the world. The cries, the desperate searches, the screams of people wandering among lifeless bodies, testify to the depth of this catastrophe. Iran needs immediate action. At this moment, silence is no longer neutrality, it is complicity in death.
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David Odde Lab retweeted
Parents looking for their children. Those evil bastards! The West must find its voice, at the very least. Trump must redeploy some of those military assets he moved to the Caribbean, pronto. Now is the time for action. Free Iran!
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Are you following @DavidOddeLab My laboratory seeks to discover how cells migrate and how tumors grow, with a major focus in brain cancer progression. Learn More at oddelab.umn.edu
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During the next session at #CancerEngineeringSummit, experts shared solutions to hard problems. Samir Mitragotri, PhD (@SMitragotri) discussed advancing cytotoxic T cell therapies. David Odde, PhD (@davidodde) shared insights on glioblastoma and the mechanics of T cell migration in cancer progression. Karen Lu, MD (@karenluMD) highlighted the power of multidisciplinary teamwork, sharing a real-world example of bridging basic science and clinical trials in ovarian cancer.
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Excited to share that our review article, "Physical principles and mechanisms of cell migration", is now published online in npj Biological Physics and Mechanics! Read it here: rdcu.be/d6oUO @davidodde @ppproven
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David Odde Lab retweeted
Very proud of my group’s presentations at the @BMESociety annual meeting, including our high school intern Lily, @Aly_Mohammadd , @matilla_roberto , and former PhD student @lsprahl (presenting his Postdoc work with @HughesLabPenn).
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Excellent presentation by @matilla_roberto from @UMNews at #BMES2024 @BMESociety on biophysical models to understand T cell migration! Congrats, Dr. Roberto Alonso Matilla. ☑️ Check out his poster later today at 3:30 -4:30 pm!
Attending #BMES2024 @BMESociety? Join Dr. @matilla_roberto from @UMNews and Dr. Steven Becker from @NCICancerBio for a presentation on interdisciplinary programs at @theNCI aimed at accelerating research in fundamental cancer biology using engineering approaches. Details ⬇️
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Get an insider's view of the research that happens in the lab of @UMNBME Professor @davidodde! The research team is using mathematical modeling and simulation, as well as live cell imaging, to study cancer cell movements. @DavidOddeLab youtu.be/HCIzi0aLkpU
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David Odde Lab retweeted
Odde lab road trip to Madtown! Retreat for our C-MITIE CCBIR U54 center with @UWMadisonLOCI @ppproven out on the terrace with some Spotted Cow and open mic.
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Shape-shifting in science?? #UMNIEM member @davidodde and a team from #Cornell and #Tuskegee are connecting #architecture to #braincancer #plants and #heartdevelopment to understand how shapes emerge from the rules of life! Read more about the research: bit.ly/4cFFehV
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David Odde Lab retweeted
Enjoyed speaking at the @UMNCancer event for Doors Open Minneapolis this morning ! Goldy stopped by too. @doorsopenmpls
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David Odde Lab retweeted
Here’s the story with link to the CID article.
🚨 Research news! A new U of M study found that metformin can decrease the amount of COVID-19 virus in the body and lower the chances of the virus coming back strongly after initial treatment. Read more ➡️: bit.ly/4bhpsJm. #COVID19 | #Metformin
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A computer simulator developed by Prof. @davidodde & team was used in a phase 3 randomized clinical trial published in Clinical Infectious Diseases. @DavidOddeLab @UMNresearch @UMNCSE
🚨 Research news! A new U of M study found that metformin can decrease the amount of COVID-19 virus in the body and lower the chances of the virus coming back strongly after initial treatment. Read more ➡️: bit.ly/4bhpsJm. #COVID19 | #Metformin
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David Odde Lab retweeted
Repurposing Revisited: Exploring the Role of Metformin for Treatment of Coronavirus Disease 2019 academic.oup.com/cid/article… Commentary on our CID paper showing metformin reduced SARS-COV-2 viral load vs control, in addition to our previous papers on acute outcomes and long COVID. – at Minneapolis, MN
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