Dominic Helmerich retweeted
Our new functionalized docetaxel probe enables superior visualization of dense mitotic spindle structures during cell division by expansion microscopy!
| Journal of the American Chemical Society pubs.acs.org/doi/10.1021/jac…
Dominic Helmerich retweeted
I am super happy to share our latest article entitled "Decoding the molecular interplay of CD20 and therapeutic antibodies with fast volumetric nanoscopy", now published in Science science.org/doi/10.1126/scie…
Dominic Helmerich retweeted
🚨New Paper Alert🚨Explore our latest work on the Lysosomal BrainAtlas, now available on bioRxiv! This comprehensive resource maps lysosomal proteins in specific brain cell types and identifies SLC45A1 as a novel neuron-specific lysosomal sugar transporter doi.org/10.1101/2024.10.14.6…
Dominic Helmerich retweeted
🚨🎉Paper alert! Finally, our paper about the combination of ISM and SMLM is out! #SMLM #ISM #FLIM Many thanks to all contributing authors @NielsRadmacher, Ignacio Gallea, Ingo Gregor, @nanofein, Silvio Rizzoli and Jörg Enderlein. nature.com/articles/s41566-0…
Dominic Helmerich retweeted
I've always wanted to delve into virus imaging.🦠🔬 Please check out our newest preprint, where we introduce the use of the non-human-infecting virus, bacteriophage T4, as an effective and straightforward bio-ruler for 3D super-resolution imaging.📏 biorxiv.org/content/10.1101/…
Dominic Helmerich retweeted
📢 Excited to share our new preprint "Three-dimensional multi-target super-resolution microscopy of cells using Metal-Induced Energy Transfer and DNA-PAINT"! biorxiv.org/content/10.1101/…
#DNAPAINT #MIETPAINT #FLPAINT #SRM #MIET #FLIM @uniGoettingen
A short 🧵👇
Dominic Helmerich retweeted
🆕Out now: Our latest review explores innovative site-specific protein labeling strategies, pushing boundaries in biological imaging. Dive into the nanometer scale with us in Current Opinion in Chemical Biology.
▶️doi.org/10.1016/j.cbpa.2024.…
#ScienceTwitter #ProteinLabeling
Dominic Helmerich retweeted
My first paper at @OxfordChemistry is out in @NaturePhotonics: Single-protein optical holography! Big thanks to Emanuel Pfitzner and Philipp Kukura. We improved the sensitivity of optical holography by orders of magnitude to detect single proteins. 1/5 nature.com/articles/s41566-0…
Dominic Helmerich retweeted
🚨📢Out now: „Expansion microscopy enables 4-color fluorescence imaging of trans-synaptic protein organization.”
Discover the nanocolumn arrangement @FrontNeurosci:
Link ▶️: doi.org/10.3389/fncel.2024.1…
Dominic Helmerich retweeted
PicoRulers are new optical rulers for validating #SuperResolution #Microscopy performance. These rulers are based on the PCNA protein and use precisely positioned unnatural amino acids at 6 nm spacing, specifically labeled using click chemistry. More info: bit.ly/41aDJUf
Dominic Helmerich retweeted
Using Click Chemistry To Improve Viral Infection Modeling: New approach to virus visualization and labeling
chemistryviews.org/using-cli…
Dominic Helmerich retweeted
NEW📰🚨:"Protein-based PicoRulers set new standards for the verification of sub-10 nm super-resolution microscopy methods under cellular conditions."
▶️onlinelibrary.wiley.com/doi/…
Dominic Helmerich retweeted
Good news for the world of high-resolution #microscopy: @unnaturalGerti @LabSauer @RVZ_Wuerzburg present biocompatible molecular rulers for calibrating the latest super-resolution microscopy methods @advscinews! ➡️ uni-wuerzburg.de/en/news-and…
ALT PicoRuler: Protein-based molecular rulers make it possible to test the optical resolution of the latest super-resolution microscopy methods on biomolecules in the sub-10-nanometre range under realistic conditions. (Image: Gerti Beliu / University of Würzburg, created with DALL-E 3)
Dominic Helmerich retweeted
#Microscopy: The penetration of #viruses into cells can now be tracked with unprecedented accuracy - thanks to @LabSauer @unnaturalGerti @RVZ_Wuerzburg and their innovative design for #pseudoviruses @acsnano
➡️ uni-wuerzburg.de/en/news-and…
ALT An innovative method makes it possible to precisely detect viruses and visualise them in three dimensions. This opens up new horizons for virus research. (Image: Gerti Beliu / RVZ, created with DALL-E 3)
Dominic Helmerich retweeted
🚨🆕"What if we could map viral infections in 3D?" Now we can!
Discover our #clickVSV technology in our latest publication @acsnano:
▶️pubs.acs.org/doi/10.1021/acs…
A joint effort of the labs of @GeorgGasteiger and @unnaturalGerti at @Uni_WUE
#Virology #VirusResearch #Science
Dominic Helmerich retweeted
📢New Paper: "Expansion microscopy enables 4-color fluorescence imaging of synaptic protein organization with 20 nm spatial resolution."
➡️Here´s the link: doi.org/10.1117/1.NPh.10.4.0…
#FluorescenceFriday
Dominic Helmerich retweeted
🚨New preprint: “Two-dye imager (TDI)-DNA-PAINT allows up to 15-fold faster imaging at higher resolution and whole cell imaging in 4 hours.”
▶️Link: biorxiv.org/content/10.1101/…
Dominic Helmerich retweeted
Our new preprint is out. FL-SMLM + ISM =💪Check it here👉Doubling the resolution of single-molecule localization microscopy with image scanning microscopy biorxiv.org/content/10.1101/…
Dominic Helmerich retweeted
🔬Exciting news from our lab! Our recent paper uses #dSTORM to redefine our understanding of SARS-CoV-2 entry-receptors. Endogenous ACE2 is expressed as monomer at low densities of 1-2 receptors/µm2 in the plasma membrane❗️
➡️onlinelibrary.wiley.com/doi/…
Dominic Helmerich retweeted
Out in ACS Nano now, we make metal-induced energy transfer (MIET) imaging accessible to fluorescent proteins. We show nanometer resolution axial mapping of living cellular and subcellular components across multiple time scales, from a few ms to hrs.
pubs.acs.org/doi/10.1021/acs…
