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loop_enhancer

@EnhancerLoop

Enhancer papers manually picked by @IvKrivega. Views are my own. #chromatin #enhancer #synteticbiology #geneediting

 San Francisco, CA
linkedin.com/in/ikrivega
Joined July 2020
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Photo by loop_enhancer (@EnhancerLoop)Photo by loop_enhancer (@EnhancerLoop)
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cell.com/trends/genetics/ful…
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nature.com/articles/s41596-0…
Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture

Capture-C: a modular and flexible approach for high-resolution chromosome conformation capture

Nature Protocols - Capture-C detects DNA regions in close proximity in the nucleus, relying on oligonucleotide probes to enrich fragments of interest. This protocol describes several variations of...

nature.com
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Here, we introduce RedChIP, a technique combining RNA–DNA proximity ligation and chromatin immunoprecipitation for identifying RNA–chromatin interactions mediated by a particular protein.  pnas.org/content/119/1/e2116…
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CTCF-mediated loops are neither required for the interaction of the Sox2 promoter with distal enhancers, nor for its expression biorxiv.org/cgi/content/shor…
Image from loop_enhancer (@EnhancerLoop)
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Assessing genome-wide dynamic changes in enhancer activity during early mESC differentiation by...

Assessing genome-wide dynamic changes in enhancer activity during early mESC differentiation by...

Abstract. Embryonic stem cells (ESCs) can differentiate into any given cell type and therefore represent a versatile model to study the link between gene r

academic.oup.com
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Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops cell.com/cell/fulltext/S0092…
Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops

Jpx RNA regulates CTCF anchor site selection and formation of chromosome loops

Jpx RNA regulates chromosome looping throughout the genome by releasing CTCF from chromatin, thereby determining where CTCF binds, how anchor sites are selected, and how genome architecture is...

cell.com
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Epiphany: predicting Hi-C contact maps from 1D epigenomic signals biorxiv.org/cgi/content/shor… #journals #feedly
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motion of smaller 1 kbp regions depends strongly on local disruption to chromatin fibre structure marked by H3K27. This also influenced locus configuration dynamics by modulating promoter-enhancer loops associated with protein bridging.  biorxiv.org/content/10.1101/…
Transcription modulates chromatin dynamics and locus configuration sampling

Transcription modulates chromatin dynamics and locus configuration sampling

In living cells the 3D structure of gene loci is dynamic, but this is not revealed by 3C and FISH experiments in fixed samples, leaving a significant gap in our understanding. To overcome these...

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