Working on the spread of antibiotic-resistance plasmids and the role of plasmid-encoded CRISPR-Cas currently postdoc @institutpasteur previously phd @ETH
Paris, France
Joined May 2019
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fabienne.benz retweeted
Massive effort lead by the amazing @FabBenz to discuss the present and future of CRISPR-based antimicrobials ⚡
fabienne.benz retweeted
Two Postdocs (Lausanne, Switzerland)
Bacterial genomics in the context of evolutionary epidemiology, with potential projects including antibiotic resistance, HGT and plasmid dynamics.
with @sonjaklehtinen
at University of Lausanne
More details: iddjobs.org/jobs/bacterial-g…
fabienne.benz retweeted
For the past two years, we have been working on a novel approach to identify origins of transfer by conjugation in plasmids from any bacterial species.
We are thrilled to see this work now published in @NatureMicrobiol after thorough peer review!
nature.com/articles/s41564-0…
fabienne.benz retweeted
Fantastic PhD Opportunity on plasmid-phage interactions in Manchester with @c_igler and Mike Brockhurst👇also: the time in Germany would be spent in my lab
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fabienne.benz retweeted
Make sure you don't miss it! 🤓
Excited to share our last collab paper in @NatureComms on the structure & interference mechanism of the mysterious 𝗧𝘆𝗽𝗲 𝗜𝗩-𝗔 𝗖𝗥𝗜𝗦𝗣𝗥-𝗖𝗮𝘀 system!! 🧬🚀
🔗nature.com/articles/s41467-0…
🧵 by @patrick_pausch below!
fabienne.benz retweeted
Should I stay or should I go? 🎶
In a new opinion piece, @c_igler, Andrina Bernhard and I discuss how conjugative plasmids and temperate bacteriophages balance vertical and horizontal transmission: ecoevorxiv.org/repository/vi…
Our framework illuminates many sides of MGE biology (1/7)
fabienne.benz retweeted
1/8. 𝐧𝐜𝐑𝐍𝐀𝐬 often fly under the radar... but they're vital in bacteria-phage conflicts & beyond. Curious 𝙬𝙝𝙮!? 🤔
Here, we dive into their immune roles, plasticity, and discuss their hidden potential! 🧬🚀
🔗:cell.com/trends/microbiology…
fabienne.benz retweeted
Meet The Shielded Plasmid🛡️🧬
Our new @Nature paper reveals how plasmids outsmart bacterial defenses during conjugation.
It's all about being in the right place at the right time! The positioning of anti-defense genes boosts transfer efficiency🧵(1/7) nature.com/articles/s41586-0…
ALT Illustrated by @Irisburstein
fabienne.benz retweeted
We are hiring! 1 PhD position available within our newly-funded @ERC_Research project
#PHAGEPRO @LMU_Muenchen. We are looking for a candidate with a strong background in bioinformatics! ChatGPT-generated applications will not be considered. Watch👇to learn more about the project
ERC Starting Grant for PHAGE-PRO – Prof. Carolin Wendling🌟
@ERC_Research has awarded the project PHAGE-PRO with an #ERC Starting Grant.
🔎What is #PHAGE-PRO about?
👇Watch the video👇
👉 Prof. Carolin Wendling explains how PHAGE-PRO offers a novel approach to combating bacterial infections using phage therapy – a promising opportunity amidst the growing problem of antibiotic resistance.
💡 Traditional phage therapy faces challenges like slow phage identification and limited effectiveness. Prof. Carolin Wendling aims to overcome these obstacles by using prophages (viral DNA integrated into bacterial genomes) in probiotics to enhance their in vivo efficacy.
👉Learn more about this year's 5 ERC Starting Grants at #HelmholtzMunich in our news:
🔗t1p.de/ch7ex
@CCWendling @DeshwalSoni @ie_fernandez @Pseudomanifold @LungHealthMUC @HorizonEU @EUScienceInnov @ERCGrantees @LMU_Muenchen
#ERCStG #EUfunded #FrontierResearch #EuropeanResearchCouncil #StartingGrants #EU #PhageTherapy
fabienne.benz retweeted
So glad to see this out!
It was definitely a labor of love, but it has become my new blueprint of how I think about AMR evolution. We aimed to highlight how much we've learnt as a field, and especially, how much we still *don't* know 1/4
Thrilled to see the first review article from my lab out in advance @AnnualReviews, helmed by @Celia_Sqe: From Petri Dishes to Patients to Populations:
Scales and Evolutionary Mechanisms Driving Antibiotic Resistance
annualreviews.org/content/jo…
fabienne.benz retweeted
Sedentary chromosomal integrons (SCIs) are biobanks of anti-phage defence systems! In a huge collaboration with the @amazeld lab, we showed that these flexible genetic platforms encode known defences and further discovered 16 new systems. A thread (1/n)
doi.org/10.1101/2024.07.02.6…
fabienne.benz retweeted
Happy to share our results on #plasmid #evolution. We show that plasmid contribution to gene transfer corresponds mostly to transfer of the plasmid entity rather than gene transfer between plasmids and chromosomes. doi.org/10.1016/j.cub.2024.0… Great work by Samer Kadibalban!
fabienne.benz retweeted
Thrilled to see this in print! Huge congratulations to all the co-authors, especially @FabBenz and @SarahCamara94 for leading this incredible work. So proud! 🙌
Type IV-A3 CRISPR-Cas systems drive inter-plasmid conflict: Type IV-A3 rely on host I-E adaptation machinery to acquire spacers&mediate inter-plasmid competition via DinG helicase-assisted transcriptional interference @FabBenz @SarahCamara94 @rafapinilla92 cell.com/cell-host-microbe/f…
fabienne.benz retweeted
Thrilled to see this one out! It's been so much fun to go over so many great papers from the last years 🙏🏼
Going viral: The role of mobile genetic elements in bacterial immunity
@BeatrizBeamud @FabBenz @dbikard review work revealing that most bacterial defense systems are carried by mobile elements, indicating complex evolutionary forces driving immunity cell.com/cell-host-microbe/a…
fabienne.benz retweeted
Are you studying #polymicrobial interactions? #Bacteriophages? Competition/Cooperation of two or more species? Use my new standardized device for your experiments.
Coming soon...
Thanks to the @UZH_en Innovation Hub for funding.
fabienne.benz retweeted
Join my team in @CbiToulouse, a multidisciplinary research center grouping teams that study fundamental aspects of structure & function of complex biological systems.
#Toulouse is vibrant dynamic city ☀️ offering high quality of life & near 🏔️ & 🏖️
fabienne.benz retweeted
We're recruiting! Multiple postdoc and PhD positions at the University of Lausanne. Official adverts will be out soon, but you can have a sneak peek. Informal enquires are encouraged - if you like our papers, we want to hear from you! sites.google.com/view/sonjal…
fabienne.benz retweeted
"The mysteries of microbial mobilizable genetic elements" - This is what happens when MGE aficionados can't stop debating about mobile genetic elements in the best place to do it! Such interesting discussions while writing it with @doctor_jams, @ccoluzzi1 and @epcrocha!
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fabienne.benz retweeted
Looking for a postdoc? Fascinated by phage-bacteria interactions?
2-y position at the University of Copenhagen (UCPH), based at UCPH PLEN w/ @LeiseRiber, in collab with our team at UCPH Micro! 🧬🔬 🇩🇰
jobportal.ku.dk/videnskabeli…
Please share with interested colleagues!