Brent Fogel

Read from @fogellab "multiWGCNA: an R package for deep mining gene co-expression networks in multi-trait expression data" #BMCBioInformatics for study of disease-associated gene networks across time or space bmcbioinformatics.biomedcent… @TommasiniDario @UCLANeurology @UCLAHealthNews

"Alterations in oligodendrocyte transcriptional networks reveal region-specific vulnerabilities to neurological disease" in @iScience_CP sciencedirect.com/science/ar… @TommasiniDario @rachelgiulia @Kathie0309 collaboration with @HinmanLabUCLA @NAF_Ataxia @UCLAHealthNews @UCLANeurology

Hadjinicolaou & Ngo #SETX confirmed functionally to cause a rapidly progressive early‑onset #neurogenetic disorder w severe polyneuropathy @Fogellab collab w C Bennett Al La Spada & Grace Yoon #ALS4 @UCLANeurology @UCLAHealthNews @SickKidsNews @NAF_Ataxia rdcu.be/cDtVw

Wong & @Fogellab report a woman & family with acute dystonia to ondansetron, prochlorperazine, and metoclopramide. #Pharmacogenomic testing revealed the CYP2D6 enzyme *41 allele as the likely cause of the medication-induced dystonia. @UCLANeurology rdcu.be/cu6pS

A pleasure to speak in #AANAM S13: Advances in General Neurology on cortical oligodendrocyte gene networks in tauopathy. Wonderful talks showcasing excellent clinical & basic science in General Neurology! Happy to participate. @HinmanLabUCLA @FogelLab @UCLANeurology @AANMember

Happy to speak in Neuroscience in the Clinic session at #AANFC with Matthew Harms, Andrea Gropman, Anne Chiaramello, Suman Jayadev, & Kathie Ngo today. Fantastic presentations! Making progress toward precision health in common neurodegenerative disease. @AANMember @UCLANeurology

Presenting on Collaborative Genetic Platforms for Ataxia at SCA & ARCA Global meeting. #AtaxiaGlobal2020 @ataxia_global @NAF_Ataxia @UCLANeurology #RareDisease

Presenting at SCA & ARCA Global meeting on ARCA cohorts in the US #ataxiaglobal2020 @ataxia_global @NAF_Ataxia #raredisease @UCLANeurology

It was to great to speak in the #neurogenetics session at #ANA2020 with Matthew Harms, Stephan Zuchner, Monkol Lek, and David Dai today. Great talks! Exciting happenings in the genetics of neurodegenerative disease. @theFourier2k @szuchner @alicechenp @UCLANeurology

Congratulations to Dona Aboud Syriani for winning the 2020 Science Dean’s Prize at UCLA Undergraduate Research Week for her work on the prevalence of RFC1 in North America ng.neurology.org/content/6/3… #ataxia #raredisease @ROCAtaxia @UCLANeurology @UCLAHealthNews @NAF_Ataxia

Syriani et al. Prevalence of RFC1-mediated spinocerebellar ataxia in a North American ataxia cohort now published in Neurology Genetics ng.neurology.org/content/6/3… #ataxia #raredisease @ROCAtaxia @UCLANeurology @UCLAHealthNews @NAF_Ataxia

Ngo et al Diagnostic Ceiling for #Exome Sequencing in Cerebellar #Ataxia. doi.org/10.1002/humu.23946 Despite advancements ~50% is current upper limit of WES diagnosis. Better genome-wide methods needed to improve this. #raredisease @NAF_ataxia @UCLANeurology @UCLAHealth @ROCAtaxia

@FogelLab presenting ePoster today on male infertility in #ataxia with oculomotor apraxia type 2 (AOA2) at #AANAM #AANAM2019 @AANMember @UCLANeurology @NAF_Ataxia

For an introduction to the Clinical Application of #NextGenerationSequencing to the Practice of #Neurology see Rexach et. al. thelancet.com/journals/laneu… just published by @TheLancetNeuro @UCLANeurology @UCLAHealth #neurogenetics #precisionhealth #ataxia #rarediseases #exome #genome

New research from @fogellab and collaborators discovers Disruption of Spermatogenesis and Infertility in Ataxia with Oculomotor Apraxia Type 2 #AOA2 published in @TheCerebellum rdcu.be/bntD2 #ataxia @UCLANeurology @NAF_Ataxia @UCLAHealth

Read @Fogellab case report on how #exomesequencing led to successful treatment for a child with #ataxia due to a rare #genetic vitamin deficiency rdcu.be/9IY2 #raredisease #exome #neurogenetics #precisionhealth @UCLAHealthNews @NAF_Ataxia @UCLANeurology

@FogelLab speaking today on the use and clinical benefits of Whole #Exome Sequencing for Neurologic Disease at #AANAM! #RareDiseases @UCLANeurology @NAF_Ataxia #ataxia #DNA

@FogelLab presenting today on challenges in genetic testing - making sense of variants of uncertain significance! #AANAM #GeneticTesting #exome #ataxia @UCLANeurology @NAF_Ataxia

@FogelLab Valera et al poster Prevalence of #SCA36 in US displayed at #AANAM 2018 today! #ataxia @NAF_Ataxia @UCLANeurology