@FunImmune

Functional studies of autoimmune disease-associated variants. Interest on ncRNA-regulated pathways. Group led by Dr. Castellanos-Rubio and Dr. Santin at @upvehu

 Euskal Herria
Joined April 2020
  • Tweets553
  • Following471
  • Followers284
133Media
Nice first day at the #EASD2026 meeting! 🔝🔝🔝 We've had the opportunity to present our work on virus-induced non-canonical translation in pancreatic beta cells. 🤔 Are they a novel source of #T1D neoantigens?
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We are at the #EASD2026 in Milan! 👏👏👏 Do not miss our short talk about virus-induced non-canonical translation in beta cells ⬇️⬇️
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So excited to share the last contribution of our lab in collaboration with Prof. Ghosh’s lab in @Columbia. Another lncRNA harboring a genetic variant that contributes to risk to develop #IBD. Great collaborative work! cell.com/immunity/abstract/S…

An inflammatory bowel disease-linked lncRNA suppresses transcription factor T-BET expression in T...

The role of noncoding lncRNAs in human disease is difficult to ascertain. Yang-Fischer et al. identify lnc15 (2310015A10Rik/ENSMUSG00000097729) as a cytoplasmic brake on intestinal inflammation....

cell.com
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Muy contentas de que una de las líneas del lab haya sido financiada con un #PID2025. Seguiremos estudiando el papel del #RNA en la #inflamacionintestinal. Eso sí, tocará priorizar y reajustar…
Agencia Estatal de Investigación@AgEInvesJul 16
Publicada Propuesta de Resolución Provisional de la convocatoria Proyectos Generación de Conocimiento #PID2025 para impulsar la #investigación, generación de #conocimiento y búsqueda de soluciones a los grandes desafíos de la sociedad. 🔗aei.gob.es/noticias/convocat…
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FunImmune Lab's living a celebration!! 🥳🥳🥳 @bergara_leire, we missed you! 💜
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FUNctional genetics of IMMUNE disorders retweeted
Izortze 🇵🇸@IzorbarakaJul 11
Bizitzaren unerik onenean gaude. #1981
Gorka Orive
@gorka_oriveJul 11
Las evidencias científicas sugieren que el ser humano no envejece de forma lineal, si no más bien gradual. Un envejecimiento en 3-4 olas o periodos clave.
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Just arriving to Barcelona to join the #EISG2026. Looking forward to enjoy 3 days full of good science! 😊
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Yesterday, one of our group's PIs, Izortze Santin, was promoted to Full Professor of Biochemistry and Molecular Biology. Congrats! Zorionak! 🥳🥳
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Last day at the #Ribored2026. It has been an epic journay! Thanks to the speakers for their inspiring presentations and thanks to the organizers for an outstanding meeting! See you in #Ribored2028!!
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Nice presentation of our PhD student @IzeiPascual at the #RiboRed2026 meeting. He has shown the relation between PUS10 and epitranscriptomics with intestinal inflammatory diseases. 🔝🔝🔝 Well done, Izei! 👏👏
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FUNctional genetics of IMMUNE disorders retweeted
Sociedad Española del RNA@ribored_esMay 13
Our first scientific session topic is "Therapeutic RNAs and RNA in disease". Our speakers have covered several diseases and innovative treatments. Thanks to all of them! Marc Talló-Parra, Lorea Blázquez, Aarón Ramirez, Ángela Pérez and Julián Valero.
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Excited to be at the #RiboRed2026 meeting! Today, our postdoc @AaronRamirez02 presented his work on virus-induced non-canonical translation and the impact of micropeptides in type 1 diabetes 👏👏👏 Great discussions and inspiring science! 🧬✨
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Last contribution from the lab leaded by Ghosh lab at @Columbia. More #lncRNA fun this time as a mouse model of oral tolerance to #gluten. nature.com/articles/s41590-0…

The long noncoding RNA lnc13 restrains inflammatory responses to maintain oral tolerance to gluten

Nature Immunology - Ghosh and colleagues examine the mechanism underlying the long-noncoding RNA lnc13-mediated regulation to gluten tolerance. The authors show lnc13 restrains CD8αβ+...

nature.com
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Muchas gracias a @adirmu y @IMIB_RMurcia por darnos la oportunidad de presentar nuestro trabajo en este foro. Siempre es un placer compartir nuestra investigación con personas con diabetes tipo 1 y sus familiares. Hasta la próxima! 💜
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Hoy, la investigadora de nuestro grupo, Izortze Santin, participará como ponente en el V. Ciclo de Investigación y Ciencia en Diabetes, organizado por @adirmu @IMIB_RMurcia
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Investigación básica en Diabetes. Dream team! 🙌🙌🙌 #FSED2026
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So happy to share our last contribution published in @CellReports and leaded by @ARNesLab describing a novel #RNA regulatory layer in #PDAC. Thanks for involving us! cell.com/cell-reports/fullte…

Regulatory elements in the Sox9 locus license the initiation of pancreatic ductal adenocarcinoma

Ballester et al. reveal that developmental enhancers reactivated during pancreas regeneration can be hijacked by oncogenic KRAS to promote cancer initiation. We identify the enhancer-derived lncRNA...

cell.com
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@upvehu @biobizkaia @Ikerbasque @bergara_leire @Izorbaraka @AinaCastellanos
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Hoy @AaronRamirez02, investigador postdoc en nuestro grupo, ha presentado su trabajo sobre el efecto de las infecciones víricas en la traducción no canónica de la célula beta, en el congreso #FSED2026. Gran presentación! 👏👏👏
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FUNctional genetics of IMMUNE disorders retweeted
Islet Biology Lab - UMH@isletbiologylabApr 15
Empezamos el Congreso de la #FSED2026 con el curso organizado por el Grupo de Trabajo Experimentación Básica en Diabetes.
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