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GNPN

@GNPNetwork

Our researchers use #synbio to engineer genomes that produce natural products with potential pharmaceutical, industrial and agricultural value. Funded by @NIGMS

 United States
gnpn-genome.org
Joined October 2015
  • Tweets79
  • Following238
  • Followers199
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Photo by GNPN (@GNPNetwork)Photo by GNPN (@GNPNetwork)Photo by GNPN (@GNPNetwork)Photo by GNPN (@GNPNetwork)Photo by GNPN (@GNPNetwork)Photo by GNPN (@GNPNetwork)Photo by GNPN (@GNPNetwork)
.@FastCompany profiles our network member Christina Smolke of @StanfordBioE & her company's efforts to use yeast to engineer safer opioids more efficiently: fastcompany.com/3066129/can-…
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Could this be you? Postdoc and PhD position available on computational methods for natural product discovery! Plz RT connexys.nl/vacatures/wageni…
Image from Marnix Medema (@marnixmedema)
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.@AnneOsbourn1 on her lab’s methods for pathway engineering & improved agro-infiltration to produce gram-scale quantities of triterpenes: ncbi.nlm.nih.gov/labs/articl… #KSsynbio

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Replying to @GNPNetwork @AnneOsbourn1 @JohnInnesCentre
.@AnneOsbourn1 gives a shoutout to plantiSMASH tool to mine plant genomes for biosynthetic gene clusters, developed in collaboration with @marnixmedema plantismash.secondarymetabol… ncbi.nlm.nih.gov/pubmed/2845… #KSsynbio
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.@AnneOsbourn1 of @JohnInnesCentre presenting on plant metabolite production, namely triterpenes & their functions in nature & pharmacology #KSsynbio
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Now talking at #KSsynbio: our network member & @StanfordBioE Professor Christina Smolke on microbial manufacturing of synthetic opioids
Replying to @GNPNetwork @yitang_ucla
.@yitang_ucla gives a shoutout to our fungal team’s heterologous expression platform for natural products in S. cerevisiae, published this week: biorxiv.org/content/early/20… #KSsynbio
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Now speaking at #KSsynbio: our network member @yitang_ucla, conference organizer & fungal natural product expert, whose lab works on biosynthesis & discovery of natural products, biocatalysis via engineering enzymes & metabolic engineering
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Jaclyn Winter of @UUtah presents her lab’s work on elucidating terpene biosynthetic mechanisms using a specialized S. cerevisiae strain for terpene production: ncbi.nlm.nih.gov/pubmed/2578… #KSsynbio
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Our network member Beth Sattely describing efforts to improve plant fitness - identification of pathways & metabolites involved in pathogen defense published in @nature: ncbi.nlm.nih.gov/pubmed/2635… #KSsynbio
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Jon Clardy describing the “unknown unknowns” concept of the unknown pathways that produce unknown natural products - a focus of our network’s research #KSsynbio
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Replying to @GNPNetwork @StanfordMed @KeystoneSymp
Chaitan Khosla addresses de-orphaning assembly line polyketide synthases, starting from our earlier work cataloguing these led by @MHillenmeyer: ncbi.nlm.nih.gov/pubmed/2430… #KSsynbio
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Our network member & @StanfordMed #ChemH Director Chaitan Khosla now giving the keynote address @KeystoneSymp on Natural Products / #synbio #KSsynbio
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Much of our network is attending the Natural Products & #synbio @KeystoneSymp in Olympic Valley. Looking forward to a great meeting! #KSsynbio
It’s out! A dream team of over 150 authors, 54 chapters, > 1000 pages and arguably the best general text available on the fungi. Very happy to have been part of it. ASM Press: THE FUNGAL KINGDOM.
Image from Neil Gow (@neil_gow)
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Bioactive Natural Products Prioritization Using Massive Multi-informational Molecular Networks pubs.acs.org/doi/10.1021/acs…
Image from Natural Products (@NatprodCbn)
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What an honour to give the opening keynote at the SIMGBM meeting in Palermo, in this wonderful palazzo! simgbm.it/notizie-simgbm/96-…
Image from Marnix Medema (@marnixmedema)
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Start teaching mycology! by Freimoser joins Stop neglecting fungi! in our community site naturemicrobiologycommunity.… & rdcu.be/vTkN
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Our new paper in Nature."SAM-dependent enzyme-catalysed pericyclic reactions in natural product biosynthesis." rdcu.be/vPrD
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Very interesting study by the Brady lab on N-acyl synthases in the human microbiome... teapaw.org/naturerevmicro/status/…
Nature Reviews Microbiology (@NatureRevMicro) profile pictureNature Reviews Microbiology@NatureRevMicro30 Aug 2017
Commensal bacteria make GPCR ligands that mimic human signalling molecules @nature nature.com/nature/journal/va…
Image from Nature Reviews Microbiology (@NatureRevMicro)
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