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Nature research paper: In situ targeted base editing of bacteria in the mouse gut go.nature.com/3VW8iuJ
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1/Explore the latest in genomics with our Random Promoter DREAM Challenge outcomes, offering insights into designing the best sequence-to-expression models. Ideal for those looking to train neural networks on genomics sequence datasets. 🧬💻 biorxiv.org/content/10.1101/…
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Nature research paper: Coordination of cohesin and DNA replication observed with purified proteins go.nature.com/493ppQg
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It would be so cool if you could put rhodopsin into yeast and get them to grow faster in the light.... cell.com/current-biology/ful…
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Sometimes, no simple way of describing the complexity of the data exists, at least not one that humans can readily interpret.
Then, faithfully representing the data is at odds with finding simple explanations.
Fig. 2e from nature.com/articles/s41592-0…
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Finally out!
We found that mRNAs are not uniformly distributed across the cytoplasm.
mRNA architecture is the strongest determinant for localization.
Subcytoplasmic location of translation controls protein output.
cell.com/molecular-cell/full…
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From AI to the Y chromosome (and everything in between)
Our editors pick their favorite research articles from 2023 go.nature.com/3uMSHnm
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Excited to share our latest studies published in Nature yesterday “Single-cell CRISPR screens in vivo map T cell fate regulomes in cancer”@Nature @StJudeResearch
nature.com/articles/s41586-0…
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In a major milestone for science, for medicine, and for patients, the world’s first CRISPR drug has been approved in the UK.
“A new treatment for sickle-cell disease and transfusion-dependent β-thalassemia has been authorised by the Medicines and Healthcare products Regulatory Agency (MHRA) for patients aged 12 and over after a rigorous assessment of its safety, quality and effectiveness.”
Congratulations to the many scientists, doctors, patients, and industry leaders who made this development possible.🍻
gov.uk/government/news/mhra-…
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Happy Sc2.0 day. 10 new papers published today in Cell Genomics, Cell and Molecular Cell. Telling the story of 8 more completed chromosomes (including ours) and a tRNA neochromosome and bringing more than half the syn genome together into a single cell.
cell.com/cell-genomics/curre…
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Congrats to all of @iGEM HQ for an incredibly amazing and impressive 2023 Grand Jamboree!
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CRISPR offers an alternative to viral delivery – if efficiency can be improved. #AdFeature with @GenScript
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Even when exposed to diverse wild microbes, laboratory mice still mount strong type 2 helper T cell responses to various allergen challenges, a new @SciImmunology study reports. scim.ag/4qa
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Translocation of linearized full-length proteins through an engineered nanopore under opposing electrophoretic force go.nature.com/3PpPTDi
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Now online! Stepwise emergence of the neuronal gene expression program in early animal evolution dlvr.it/SwLzrB
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Our featured article: Deafness: from genetic architecture to gene therapy go.nature.com/3nSfeMF #Review by Christine Petit, Crystel Bonnet & Saaïd Safieddine @institutpasteur @univ_paris_cite @CNRS
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Irène Joliot-Curie was a battlefield radiologist, activist, politician, and daughter of two of the most famous scientists in the world: Marie Skłodowska and Pierre Curie.
Discover her journey to her own Nobel Prize: bit.ly/2D7FAzk


























