CEO and Co-founder of Wobble Genomics Tweets are my own and do not reflect Wobble Genomics. TAMA creator/developer https://xitter.cf/t.co/eNhbhPbF2x
Edinburgh, Scotland
Joined July 2017
- Tweets6.1K
- Following493
- Followers819
- Likes8.7K
Richard Kuo retweeted
ESMO25 & SABCS25 will dramatically reshape breast cancer treatment. We’re preparing an outstanding program for Miami Breast 2026 (March 5-8) to unpack the impact of these upcoming paradigm shifts. Don’t miss it: free registration using the code TARANTINO! registration.gotoper.com/mbc…
Richard Kuo retweeted
How to write a scientific paper in fifteen steps. #ScientificPaper #PaperWriting @PLOSCompBiol
journals.plos.org/ploscompbi…
Richard Kuo retweeted
SG is a highly effective ADCs, and when used adequately, it saves lives. This includes careful management of toxicities, with prophylaxis when indicated. In this article we review the data & provide RW perspectives on the management of toxicities with SG. academic.oup.com/oncolo/adva…
Richard Kuo retweeted
Strobealign v0.16.0 has been released. It comes with both runtime and accuracy improvements. Full changelog here github.com/ksahlin/strobeali…
Richard Kuo retweeted
Release of DeepVariant 1.8. Large speed improvement (~67% faster) via small model for easy sites. New Pangenome-aware option. Reduces error by ~30% for vg-mapped WGS ~10% for BWA WGS ~5% BWA exome. New config for custom model users, see release notes 1/3
github.com/google/deepvarian…
ALT Runtime figure for new version of DeepVariant with and without small model. Showing reduction in runtime of 155 minutes to 101 minutes with Illumina, 174 minutes to 71 minutes with PacBio, and 295 minutes to 114 minutes with Oxford Nanopore.
Richard Kuo retweeted
Do not miss this awesome special issue! Lots of great contributions in LRS #genomics and #trancriptomics
The Long-read sequencing Special Issue is now LIVE! Guest-edited by @ahoischen, @sedlazeck, and @anaconesa!
Richard Kuo retweeted
#Genomics is revolutionising how we understand #GeneticMaterial, offering incredible insights into how genes 🧬 function and interact. This session will explore how combining data from multiple #Biological layers—genomics, proteomics, #Metabolomics, and more—is unlocking new breakthroughs💫
✨ Davide Gianni, Senior Director Functional Genomics in Discovery Sciences, #BioPharmaceuticals R&D, @AstraZeneca
✨ Debora Lucarelli, Chief Technology Officer, @tagomics
✨ @perman_jorayev, Ph.D., Investor, @AmadeusCapital
✨ Frances Stocks Allen, Partner, @CooleyLLP
✨@GenomeRIK, CEO, @WobbleGenomics
#TechBio #TechBioUK #biotech
I'll be taking part in a panel discussion at the BIA Techbio event on October 16. Excited for the discussion!
At TechBio UK 2024, we're diving deeper into the future of healthcare with our #Genomics Track: 'Beyond genomics – delivering on applications of #Multiomics.' 🚀 ➡ ow.ly/Iqh450TnRGs
This session will explore how combining data from multiple #Biological layers—genomics, proteomics, #Metabolomics, and more—is unlocking new breakthroughs. 💫
📌 Davide Gianni, Senior Director Functional Genomics in Discovery Sciences, #BioPharmaceuticals R&D, @AstraZeneca
📌 Debora Lucarelli, Chief Technology Officer, @tagomics
📌 @perman_jorayev, Ph.D., Investor, @AmadeusCapital
📌 Frances Stocks Allen, Partner, @CooleyLLP
📌 @GenomeRIK, CEO, @WobbleGenomics
Special thanks to our headline supporter
@EliLillyandCo and event supporters @ASTRAZENECAUK, @awscloud, @Citeline, @CooleyLLP, @HSBCInnovation, @JNJNews and @lifearc1
👏
#TechBio #TechBioUK #Biotech
Richard Kuo retweeted
This year’s medicine laureates Victor Ambros and Gary Ruvkun studied a relatively unassuming 1 mm long roundworm, C. elegans.
Despite its small size, C. elegans possesses many specialised cell types such as nerve and muscle cells also found in larger, more complex animals, making it a useful model for investigating how tissues develop and mature in multicellular organisms.
Read how the 2024 medicine laureates’ investigations into C. elegans revealed an entirely new dimension to gene regulation: bit.ly/4dlPE6f
#NobelPrize
Richard Kuo retweeted
BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.
Richard Kuo retweeted
Today I will be speaking at the @NeuroAlc, hosted by Prof @NietoAngela @BCBHubCSIC @CSICval @i2sysbio
Richard Kuo retweeted
At #ECCB2024? Do not miss the highlight talk presentation of @Conesa_Lab member Alejandro Paniagua about our @ELIXIREurope tool #SQANTI3, at 10:15 h at Teatro Room. @HiTSeq @PacBio @nanopore @LongtrecEU @i2sysbio @BCBHubCSIC . Thanks to @CSIC INFRAS2024 for travel support!
Richard Kuo retweeted
making a lot of pairwise alignments (PAF) and needed a way to confirm validity of both coordinates and alignment github.com/ekg/pafcheck
Richard Kuo retweeted
Super exciting to see what the future holds for nanopore beyond DNA and RNA sequencing nature.com/articles/s41586-0…
Richard Kuo retweeted
Sebra: @PacBio Iso-Seq in pre-implantation embryo find novel isoforms rich in antisense and intergenic. Conserved in primates, suggesting driving recent evolution.
pubmed.ncbi.nlm.nih.gov/3790…
Richard Kuo retweeted
Use of 26 @PacBio Iso-Seq cell line data to build a RNA foundation model LoRNA to predict transcriptome architecture, including isoform abundance, exonic structures, and variant pathogenicity. #bioinformatics
biorxiv.org/content/10.1101/…
Richard Kuo retweeted
We've updated the @PacBio Kinnex single-cell RNA SMRT Link v13.1 troubleshooting guide to cover what are the metrics you should expect and how to analyze not officially tested kits such as GEM-X. #bioinformatics
pacb.com/wp-content/uploads/…
Richard Kuo retweeted
Me + @opentrons + KAUST on how you can automate @PacBio Kinnex kits :-)
Join Opentrons, PacBio, and Angel Angelov, PhD - Staff Scientist at KAUST Core Laboratories! Learn how to automate your PacBio Kinnex library prep workflow with Opentrons robots and understand the benefits of automating long-read sequencing library prep. Don’t miss out on this opportunity to enhance your genomics research with cutting-edge automation! 🔬💡
🗓 Date: September 12, 2024
🕗 Time: 8:00 AM (PST) | 11:00 AM (EST) | 5:00 PM (CET)
👉 Register Now: bit.ly/4dwuRxp
Richard Kuo retweeted
Our study on methods to detect subgenomic RNAs (sgRNA) is now out. This is work from Thomas Baudeau (from @CamilleMrcht and @m_salson Mikaël Salson's groups), who visited my group last summer. doi.org/10.1093/nar/gkae687 1/5
Richard Kuo retweeted
Very excited to share that our @EoscPortal OSCARS proposal was selected for funding! In the next 2 years, we'll collaborate with @erga_biodiv to develop open-source pipelines for #SQANTI3 and #longreads supported genome annotation oscars-project.eu/oscars-fir… @ELIXIREurope @BCBHubCSIC
