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Herman Sillje

@HSillje
Joined August 2022
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Proud to see our state of the art review about novel insights of PLN cardiomyopathy being published in JACC:BTS! Reassessing the Mechanisms of PLN-R14del Cardiomyopathy: From Calcium ... sciencedirect.com/science/ar…
Image from Herman Sillje (@HSillje)
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@CircRes Dec 8th Issue is Out! ahajrnls.org/3wPOBJJ Cover: Immunofluorescent staining of cardiomyocytes from mice affected by PLN-R14del mutation (magenta) showing severe disorganized sarcoplasmic reticulum (SR, cyan) which leads to cell necrosis;nuclei-blue.
Image from Circulation Research (@CircRes)
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Exciting breakthroughs in PLN-R14del cardiomyopathy! Our latest research has just been published in Circulation Research. ahajournals.org/doi/10.1161/…
DWORF Extends Life Span in a PLN-R14del Cardiomyopathy Mouse Model by Reducing Abnormal Sarcoplas...

DWORF Extends Life Span in a PLN-R14del Cardiomyopathy Mouse Model by Reducing Abnormal Sarcoplas...

BACKGROUND: The p.Arg14del variant of the PLN (phospholamban) gene causes cardiomyopathy, leading to severe heart failure. Calcium handling defects and perinuclear PLN aggregation have both been...

ahajournals.org
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