Hi everyone. New to Twitter, high enthusiasm. Posts from any and all lab members... We study signaling & develop molecular imaging tools. Science is beautiful!
UNC-Chapel Hill
Joined August 2011
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Do you like protein engineering, dynamic molecular machines, signaling, microscopy or organic chemistry? We have exciting new projects and are hiring in a number of fields. Please take a look at hahnlab.com/positions.html
We are excited about a new biosensor technique we just published. Can image single molecule conformational changes within living cells, and can make biosensor engineering substantially easier. authors.elsevier.com/a/1dudA…
ALT Graphical abstract for Liu et al, Biosensors based on peptide exposure show single molecule conformations in live cells. Cell, 2021:Oct.11. https://doi.org/10.1016/j.cell.2021.09.026.
Fired up about our new paper by Marston et al. with 1) a biosensor approach for GEFS 2) simultaneous GEF/GTPase imaging 3) a statistical approach to dissect causality between live cell events. tinyurl.com/y5kygzb9; rdcu.be/b4fhc.
ALT The image shows the design of the GEF biosensor, multiplexed imaging of GEF and GTPase activities, and statistical methods to derive causal connections from imaging data.
iPalm of frustrated phagocytosis, taken by Ana Nogueira and Shiqiong Hu with our good friends at the @AICjanelia.
