Berlin, Germany
Joined April 2021
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- Followers62
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Very happy and proud to finally see our paper on rescuing dysferlin deficiency with muscle stem cells & #CRISPR published in @NatureComms. Big thanks to all co-authors for their great work! nature.com/articles/s41467-0… @MDC_Berlin @ChariteBerlin
Helena Escobar retweeted
A #CRISPR therapy for muscular dystrophy developed at #mdcBerlin and @ChariteBerlin is showing promise in mice.
The study was published in @NatureComms.
mdc-berlin.de/news/press/dev…
ALT scientific image of muscle fibers
Very happy to have our work featured on the cover of Mol Ther - Nucleic Acids. Beautiful image by @SilviaDiFran. mRNA-mediated delivery of CRISPR tools to edit human muscle stem cells. @SimoneSpuler @ChrisStadelmann. @MDC_Berlin @MolTherapy
Helena Escobar retweeted
We are looking for a highly motivated #PhD #candidate to work on Unveiling an unprecedented function of 3-O-sulfated heparans in the cell nucleus and its importance for #myogenesis. Applicants should contact us on [email protected] at latest by early next week! Pls RT!
Helena Escobar retweeted
Are you looking for #PostDoc opportunities in #singlecell in Barcelona? In my lab we are looking for candidates to apply for a Beatriu de Pinós fellowship to use scRNA-seq to study neurodegenerative diseases. DM if you are interested. agaur.gencat.cat/en/beques-i…
And @SilviaDiFran !
#CRISPR can repair mutations that lead to muscle atrophy. @ChrisStadelmann, @HelenaScobar & @SimoneSpuler want to use this tech for therapies. They introduced the tool into muscle stem cells using #mRNA. @MolTherapy #mdcBerlin @ChariteBerlin @helmholtz_de
mdc-berlin.de/news/press/usi…
Helena Escobar retweeted
From @MDC_Berlin researchers in @moltherapy Nucleic Acids (#MTNA): #mRNA-mediated delivery of #geneediting tools to human primary muscle #stemcells cell.com/molecular-therapy-f…
Wowww enhorabuena Diego y equipo!
El tratamiento de la diabetes con células madre ya no es ciencia ficción abc.es/salud/enfermedades/ab… a través de @abc_es
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Happy to share our latest study on using mRNA to deliver CRISPR tools to human muscle stem cells ex vivo, achieving very efficient gene and base editing in a single, selection-free step!
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Helena Escobar retweeted
Please RT. We are hiring!! computational #postdoc in #singlecell transcriptomics in #Barcelona @idibell_cat @p_cmrc Deadline of applications 13th june. More info 👇idibell.cat/es/ofertes-feina…
Helena Escobar retweeted
#Epispadie führt zu lebenslanger Inkontinenz. Kann #Stammzell-Transplantation helfen? Ein Team um @SimoneSpuler (@ChariteBerlin) führt klinische Studie durch, gefördert von @BMBF_Bund und @berlinnovation.
@HealthCapitalBB @ResearchGermany #braincityberlin
mdc-berlin.de/de/news/press/…
Helena Escobar retweeted
In the video, @SimoneSpuler and lead author Helena Escobar Fernandez now give insight into the study @JCI_insight:
youtube.com/watch?v=AgNlm9qC…
Researchers at the ECRC, a joint entity of the #mdcBerlin and @ChariteBerlin, have developed a new gene-editing technique that could lead to the first potential cell therapy for genetic muscle disorders. The team now explained its findings in @JCI_insight: mdc-berlin.de/news/press/mil…
Very happy about our cover on JCI Insight!
#Cover: Base editing repairs an SGCA mutation in human primary muscle #StemCells: buff.ly/3vmpmvH
Image: patient-derived primary muscle stem cells, fused into multinucleated myotubes in vitro following gene repair by base editing
@SimoneSpuler @ChariteBerlin
#Therapeutics
Helena Escobar retweeted
Researchers at the ECRC, a joint entity of the #mdcBerlin and @ChariteBerlin, have developed a new gene-editing technique that could lead to the first potential cell therapy for genetic muscle disorders. The team now explained its findings in @JCI_insight: mdc-berlin.de/news/press/mil…
Forschende des ECRC berichten in @JCI_insight von einer neuartigen Genschere, die möglicherweise den Weg für eine Therapie der #Muskeldystrophie ebnet. Mehr: mdc-berlin.de/de/news/press/… #mdcBerlin @SimoneSpuler @ChariteBerlin
Helena Escobar retweeted
🥼 Scientists at @MDC_Berlin show that autologous gene repaired human muscle stem cells can be harnessed for cell replacement therapies of #MuscularDystrophies.
bit.ly/32cS5G8
Check out our paper on near complete correction of a muscular dystrophy causing mutation in primary human muscle stem cells by base editing!
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Helena Escobar retweeted
Proudly presenting the peer-reviewed version of our manuscript “ACME dissociation: a versatile cell fixation-dissociation method for single-cell transcriptomics” in @Genome Biology
#ACME #SingleCell
genomebiology.biomedcentral.…
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