Researcher at Tel Aviv University. I like to play with embryo-like models to understand development.
Joined April 2018
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Iftach Nachman retweeted
New preprint!
These elongating embryo-like structures formed entirely from sheep stem cells in vitro.
They develop neural tubes, somites, neurons, and kidney progenitors — modeling post-gastrulation trunk development.
🧵👇 1/8
Our work is finally published in @Dev_Cell! We predict and affect endodermal morphotype choice in mouse #gastruloids. Great work by @NaamaFa , with key contributions from Chen Sacharen and @LaraAvni. Full paper at authors.elsevier.com/a/1jCam…
Online now: Coordination between endoderm progression and mouse gastruloid elongation controls endodermal morphotype choice dlvr.it/T7qQrb
Iftach Nachman retweeted
Batch correction of single cell sequencing data via an autoencoder architecture by Reut Danino, Iftach Nachman and Roded Sharan doi.org/10.1093/bioadv/vbad1… @IftachN #SingleCellSequencing #Bioinformatics
Iftach Nachman retweeted
Dear American friends. Our Prime Minister has a tendency to lie in his interviews for International media, so I came to help with some facts. Please pass on to your friends - and come help us, Israelis who are fighting for democracy, save our country.
Iftach Nachman retweeted
📢 New post on FocalPlane
In our biggest ever preprint list, we highlight #preprints on #bioimageanalysis and new tools and techniques in #imaging over the previous six weeks.
focalplane.biologists.com/20…
Iftach Nachman retweeted
On Friday, the sun put on a dazzling show for us. My friend @TheVastReaches and I worked hard over the last 5 days to produce this incredibly detailed 140 megapixel image to illustrate how wonderfully dynamic and beautiful our star can be. Make sure you zoom in!
Iftach Nachman retweeted
Our paper is out @ScienceAdvances! Check out how a single line of inner hair cells within the mammalian cochlea🐚 forms. Congrats to the fantastic @roecon91 @ShaharTaiber & Olga Loza. See the thread below. science.org/doi/10.1126/scia…
Why are in-vitro embryo-like models so variable, while the embryo develops so robustly?
We try to tackle this in a new preprint, using the gastruloid model and morphogenetic progression of definitive endoderm (DE).
biorxiv.org/content/10.1101/…
We believe this approach can be extendable to other structures in the gastruloid system, as well as to other organoids for controlling variability, and will also shed light on the factors that provide the embryo its morphogenetic robustness.
Kudos to @naamafa for bravely leading this effort, and to Chen Schiff for all the machine learning code!
Iftach Nachman retweeted
רבים שואלים אותי, חיים, איך ידעת לזהות במאמרך לפני שלושה שבועות שהיעד הבא של מכונת הרעל הליכודית יהיה נגיד בנק ישראל (ורק התחלנו)?
האמת היא שהתשובה קלה. בקיאות בתולדות התנועות הפשיסטיות בספרד ואיטליה. זה אחד לאחד ישראל. הנגיד במובן הזה הוא רק דוגמה.
מה היסוד של התנועות האלו?
Iftach Nachman retweeted
Link to the paper (there are many more facts and discussions to read in this excellent Opinion):
pnas.org/doi/10.1073/pnas.16…
Iftach Nachman retweeted
Somitogenesis in a dish from Human pluripotent stem cells ! here come the Somitoids and Segmentoids Olivier Pourquié @harvardmed & the Axioloids @alevlab .This will help dissecting the mechanisms of human somite formation @Nature
rdcu.be/c12OX
rdcu.be/c12Ph
Iftach Nachman retweeted
Knowing how to give a good talk is a crucial skill to have, but it's mostly not formally taught very well. Here's a 🧵on my strategy for how to prepare for the presentation, actually present it, and then answer the questions.
Iftach Nachman retweeted
Our review on synthetic developmental biology is out @ScienceMagazine!
@GMartinezAra and @KStapornwongkul discussed what developmental processes have been reconstituted/controlled so far and what tools/approaches will be the key in the next stages.
science.org/doi/10.1126/scie…
Iftach Nachman retweeted
Wow! Scientists have observed a single-cell alga evolve in real time into a multicellular organism. The transition took around a year and was caused by the introduction of a predator into the environment. nature.com/articles/s41598-0…
Iftach Nachman retweeted
In case you are wondering about how to kick start your week.
Here is the interview of our dearest developmental biologist @AMartinezArias
youtu.be/ajf1U-sZpzc
#development #sciencetwitter #AcademicTwitter
