@JAMAPsych

JAMA Psychiatry is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.

 Chicago, IL
ja.ma/tjamapsychiatry
Joined July 2009
  • Tweets13.5K
  • Following277
  • Followers58.5K
2.1KMedia
Among people with #ParkinsonDisease and mood dysfunction, #Psilocybin was associated with lower systemic markers of inflammation and mitochondrial stress after treatment. ja.ma/4idaolc

Psilocybin and Inflammatory and Mitochondrial Stress Markers in Parkinson Disease

This nonrandomized clinical trial assesses associations between psilocybin therapy and changes in systemic markers of inflammation and mitochondrial stress in people with Parkinson disease and mood...

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Early clinical studies suggest that low-intensity #FocusedUltrasound can modify symptom-relevant circuitry and may improve psychiatric symptoms, but translation will depend on safety standards, target validation, and standardized reporting. ja.ma/4j2g57A

Focused Ultrasound Neuromodulation in Psychiatry

This article explores the therapeutic potential of low-intensity focused ultrasound to modulate focal brain regions for noninvasive and reversible deep brain stimulation.

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馃挰 Viewpoint: Evaluation of large language models in #MentalHealth care should reflect the realities of psychiatric practice and should not rely on isolated institutional efforts. ja.ma/3WE4iD3
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Among patients with major depressive disorder, #MachineLearning predicted relapse with moderate accuracy, but the best model used only clinical relapse risk factors. Multimodal data did not improve prediction. ja.ma/4yDTt1p
A forest plot titled 'Forest Plot of Unimodal and Multimodal Model Performances' comparing mean balanced accuracy (SD) across unimodal and multimodal models, with data points ranging mostly between 0.5 and 0.7.

ALT A forest plot titled 'Forest Plot of Unimodal and Multimodal Model Performances' comparing mean balanced accuracy (SD) across unimodal and multimodal models, with data points ranging mostly between 0.5 and 0.7.

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Greater exposure to adverse #SocialDeterminants was associated with neurobiological abnormalities in #SchizophreniaSpectrum conditions, linking SDOHs to clinical outcomes and supporting equity-oriented approaches. ja.ma/47DbOQS

Social Determinants of Health and Neurobiology Across the Schizophrenia Course

This systematic review examines structural, functional, neurochemical, and plasticity brain changes associated with social determinants of health in individuals with, or at risk for, schizophrenia-...

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#SelectiveSerotoninReuptakeInhibitors are an essential component of perinatal mental health care, and treatment decisions in pregnancy should balance risks of untreated major depressive disorder with benefits and potential risks of treatment. ja.ma/4dYmM7b

Depression and SSRI Treatment During Pregnancy

This Special Communication outlines current evidence regarding effects of both major depressive disorder and selective serotonin reuptake inhibitor (SSRI) treatment on pregnancy and offspring...

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馃搳 Among young adults and several older age groups, increasing #CannabisUseDisorder severity challenges the notion that cannabis has low addictive potential. ja.ma/476zmgZ

Trends in the Prevalence and Severity of Alcohol and Cannabis Use Disorders Among US Adults

This cross-sectional study investigates age- and sex-specific trends in the prevalence and severity of alcohol and cannabis use disorders among US adults.

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On the day after the 10 deadliest US mass shootings, nationwide traffic fatalities increased by 14%, a rise equivalent to nearly three-quarters of the deaths during the events themselves. ja.ma/4ehpAMK

The Broader Impact of Mass Shootings on Traffic Fatalities

This study attempts to assess whether major mass shootings are associated with short-term increases in fatal motor vehicle crashes, as a potential extension of their broader mortality impact.

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馃挰 Editorial: After medication abortion or procedural #Abortion, psychotropic medication prescribing was modestly higher in the following year, but the association should not be interpreted as causal. ja.ma/4hJ7NPM

How Should We Interpret the Association Between Abortion and Mild Psychiatric Illness?

In this issue of JAMA Psychiatry, in a cohort study drawn from the Danish population registry, Steinberg et al1 concluded that neither medication abortion nor procedural abortion was associated with...

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馃挰 Viewpoint: Family-based care for #Psychosis may need to address the digital home, where #SocialMedia and #ArtificialIntelligence shape symptom interpretation, conflict, treatment beliefs, and relapse warning signs. ja.ma/3VQK88G
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A Veterans Crisis Line #CaringLetters intervention was not associated with changes in #Suicide mortality among high-risk veterans who contacted the crisis line, although the previous parent trial found greater health care use among recipients. ja.ma/4zA6FVF
A screenshot of the JAMA Psychiatry journal article title page. The brief report is titled \"Caring Letters and Suicide Mortality Among US Veterans Who Contacted the Veterans Crisis Line.\" Authors listed include Mark A. Reger, PhD, et al.

ALT A screenshot of the JAMA Psychiatry journal article title page. The brief report is titled \"Caring Letters and Suicide Mortality Among US Veterans Who Contacted the Veterans Crisis Line.\" Authors listed include Mark A. Reger, PhD, et al.

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Among adults taking #GLP1 receptor agonists who were drinking at initiation, nearly half reported drinking less alcohol during the first 3 months after starting treatment. ja.ma/3UnXo4e
A JAMA Psychiatry research letter titled Patient-Reported Changes in Alcohol Use Following Glucagon-Like Peptide-1 Receptor Agonist Initiation by Lori Uscher-Pines, PhD, et al., published online October 14, 2026.

ALT A JAMA Psychiatry research letter titled Patient-Reported Changes in Alcohol Use Following Glucagon-Like Peptide-1 Receptor Agonist Initiation by Lori Uscher-Pines, PhD, et al., published online October 14, 2026.

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馃搳 Viewpoint: #Suicide risk models are advancing, but health systems often lack the infrastructure needed to select, implement, recalibrate, and sustain them in routine care. ja.ma/4hM5o6Y

Suicide Risk Models Are Ready鈥擮ur Health Systems Are Not

This Viewpoint argues that suicide risk prediction models are advancing faster than the shared infrastructure health systems need to evaluate, select, and sustain them and proposes a federated...

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馃挰 Viewpoint: Current laws governing #ArtificialIntelligence in mental health may be difficult to enforce because key terms such as therapy, self-help, companion chatbot, and intended use are not clearly defined. ja.ma/4yQSdZH
A screenshot of a JAMA Psychiatry article titled, The Need to Clarify Regulation of Mental Health Artificial Intelligence by William R. Smith, MD, PhD, et al., published online October 14, 2026.

ALT A screenshot of a JAMA Psychiatry article titled, The Need to Clarify Regulation of Mental Health Artificial Intelligence by William R. Smith, MD, PhD, et al., published online October 14, 2026.

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Online #SportsBetting legalization was associated with more mental health-related outpatient visits and prescription use, suggesting greater demand on the behavioral health system as gambling access expands. ja.ma/4ylqq2w
Six line graphs (A-F) showing percentage point differences in prescriptions and outpatient visits for depression, anxiety, and SUD relative to legalization years, comparing men and women. All charts show an upward trend post-legalization.

ALT Six line graphs (A-F) showing percentage point differences in prescriptions and outpatient visits for depression, anxiety, and SUD relative to legalization years, comparing men and women. All charts show an upward trend post-legalization.

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馃挰 Viewpoint: Longitudinal precision functional mapping combines individualized brain network mapping with repeated imaging to distinguish trait-like illness markers from state-like symptom changes in #Psychiatry. ja.ma/4zhQbS3

Longitudinal Precision Functional Mapping in Psychiatry

This Viewpoint discusses longitudinal precision functional mapping in psychiatry.

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Among older adults, #ADHD was associated with increased risk of later mild cognitive impairment or dementia, and higher genetic liability was also associated with greater risk. ja.ma/3UpXqsi
Figure 2 displays two graphs showing cumulative incidence of MCI or dementia by age. A: ADHD diagnosis (orange curve) shows higher incidence than No ADHD (blue), HR=4.11. B: High ADHD Polygenic Risk Score (orange) shows higher incidence than Low (blue), HR=1.35.

ALT Figure 2 displays two graphs showing cumulative incidence of MCI or dementia by age. A: ADHD diagnosis (orange curve) shows higher incidence than No ADHD (blue), HR=4.11. B: High ADHD Polygenic Risk Score (orange) shows higher incidence than Low (blue), HR=1.35.

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馃挰 Viewpoint: In clinical high risk for developing #Psychosis, impaired social functioning is both a predictor of psychosis onset and a major source of disability, supporting trials that measure recovery with person-centered functional outcomes. ja.ma/4hG3Gnn

Deconstructing Social Functioning in Psychosis Risk

This Viewpoint recommends viewing recovery from social functioning deficits as a co鈥損rimary outcome among individuals at clinical high risk for developing psychosis alongside the traditional primary...

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Machine learning models using periodic health assessment data identified US Army soldiers at elevated risk of subsequent #Suicide and nonfatal #SuicideAttempt, with distinct predictors between the two. ja.ma/4yJCj3d
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Among patients with prior #SexualViolence, hypervigilance remained the highest #PTSD symptom over time, while negative alterations in cognition and mood recovered most slowly. ja.ma/4y2cfir

Prior Sexual Violence, PTSD, and Recovery After New Trauma

This case-control study investigates if trajectories of posttraumatic stress disorder (PTSD) symptom recovery after new trauma differ based on history of sexual violence.

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