Josef Fowler (@JFowlerUHCOP) profile picture

Josef Fowler

@JFowlerUHCOP

Graduate Researcher in the Garey Lab at UHCOP. Studying PPIs and C Diff

Joined August 2023
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🚨Our @biorxivpreprint is out Clostridioides difficile binary toxin CDT induces biofilm-like persisting microcolonies‼️ 🔬🦠🧫 @bruno_dupuy @institutpasteur @Samy_Gobaa @BenoitChassaing
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Cool article for this weeks @TheGareyLab journal scan. A single author? Talk about heavy lifting. pubmed.ncbi.nlm.nih.gov/3615….
Suppression of vacuolar-type ATPase and induction of endoplasmic reticulum stress by proton pump...

Suppression of vacuolar-type ATPase and induction of endoplasmic reticulum stress by proton pump...

The long-term use of PPIs inhibits lysosomal V-ATPase, leading to ER stress and ROS accumulation, which may result in an increased risk of gastric cancer. Because lysosomes and the ER are common...

pubmed.ncbi.nlm.nih.gov
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