@JLand52
Joined February 2010
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With a contemporary smartphone, capturing, transmitting, and replicating sounds and visuals is a breeze, yet replicating scents remains elusive. If you want to change this, consider joining the 2025 @DR_E_A_M Olfaction Challenge at synapse.org/Synapse:syn64743…. @jeriscience
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Can we predict what a molecule smells like from its structure? A new exchange in @ChemSenses debates this question. @KingFunk5000 @emilyjmayhew
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Doty replied, pushing back on several points. We see modern models predicting perception as half full and he sees them as half empty. buff.ly/0soT0wW

Response to Comments of Pellegrino et al.

I thank Robert Pellegrino and his associates for taking the time to read my review (Doty (2025) and to put forward what they view are its four key argument

academic.oup.com
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Doty raises a point about the limits of our odor descriptors. Here's a vial from our lab. A trained panel described it as "Musty, Ozone, Earthy, Medicinal." A perfumer smelled it and said: "The hot tub is near." We have room to improve how we describe what we smell.
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Scientists at Firmenich buff.ly/jq1TyYa and now Givaudan buff.ly/u2gP5Ow report several olfactory receptors that appear to map cleanly onto specific odor notes (earthy, grapefruit, woody, etc.).
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Replying to @JLand52 @DR_E_A_M
Building on last year's Mixture Discriminability Challenge, we're offering a dataset of 650+ blends, each assessed by trained panelists using a 51-word scent lexicon.
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My favorite part of these challenges is after the competition closes. All participants get together and work collaboratively on a manuscript summarizing key insights and where the field stands. Join us! synapse.org/Synapse:syn64743…

DREAM Olfactory Mixtures Prediction Challenge 2025

'DREAM Olfactory Mixtures Prediction Challenge 2025' (Synapse ID: syn64743570) is a project on Synapse. Synapse is a platform for supporting scientific collaborations centered around shared biomed...

synapse.org
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Joel Mainland retweeted
Monell Center@MonellSc13 Dec 2024
🧵 In case you missed it: #APPLICATIONS FOR THE MONELL SCIENCE APPRENTICESHIP PROGRAM ARE OPEN Apply (by Tuesday, December 31, 2024) on monell.org/science-apprentic…
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Joel Mainland retweeted
Monell Center@MonellSc19 Aug 2024
YALL!!! It's a wrap on the 2024 Monell Science Apprenticeship Program. And this year, it's a tie-- We have not one, but two Sense-Sational Science Award winners, Aiden and Mustafa!
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We're recruiting! The Wachowiak lab at @UtahNeurosci has postdoctoral positions available. Interested in odor coding, neural dynamics, active sensing, in vivo imaging/ephys? Check us out! Please RT. wachowiaklab.org/ #ScienceJobs #Neuroscience
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Drugs like Ozempic are great for weight loss, but they make some people feel sick. We discovered that the brain circuits mediating the appetite suppression are distinct from those that mediate nausea – a finding that may be leveraged to develop more selective GLP1-based drugs.
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Joel Mainland retweeted
Monell Center@MonellSc10 Jul 2024
Today in @Nature-- @MonellSc researchers, led by @AmberAlhadeff, share new findings that point towards a possible way to reduce adverse side effects of popular next-generation obesity medications like GLP1-based drugs, known as semaglutide and marketed as Ozempic® and Wegovy®
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Joel Mainland retweeted
DREAMchallenges@DR_E_A_M13 May 2024
Amazing @JLand52 will be presenting!
Sage Bionetworks
@Sagebio13 May 2024
Curious how to use predictive models to discriminate between odor mixtures & unravel the mysteries of our sense of smell? Join @jeriscience from @IBMresearch & @DR_E_A_M for the Olfactory Mixtures Prediction Challenge webinar today (noon PT) to learn more: synapse.org/#!Synapse:syn534…
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