Physician scientist at the University of Texas MD Anderson Cancer Center. Views are my own. @MDAndersonNews #lungcancer #endcancer
Joined September 2010
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The TUSC2 gene plays a critical role in healthy aging. Gene expression is lost in human tissues, including the brain, with aging suggesting that healthy aging could be promoted by TUSC2 gene therapy.
sciencedirect.com/science/ar…
Jack A. Roth, M.D. retweeted
I was reminded of an old paper from #eldeirylab at Penn 30 years ago👇
In vitro evaluation of a p53-expressing adenovirus as an anti-cancer drug
onlinelibrary.wiley.com/doi/…
View my updated web site:
jackarothmd.org
700+ scientific publications from my laboratory spanning 40+ years of translational cancer research can be queried by the AI chatbot without a paywall
#endcancer #OncoAlert @MDAndersonNews @AACR
@ScienceNews @LUNGevity @ASCO @aaas @AATSHQ
Jack A. Roth, M.D. retweeted
Bolton: There's a downside here to that occurred to me, and that is when Trump calls up Putin to berate him for providing Iran this intelligence. Putin says, let's make a deal, we'll cease all intelligence supply of intelligence to Iran, if you cease the supply of all intelligence to Ukraine…
Jack A. Roth, M.D. retweeted
This week @TheLancet cover
and link to their accompanying editorial
thelancet.com/journals/lance…
Jack A. Roth, M.D. retweeted
Here the Moderna flu data the FDA refused to review.
This is the most important slide from the company's study of its experimental flu vaccine-- exactly the data FDA said it wouldn't even review.
And below is a thread of relevant slides from that presentation and links to other relevant studies I wanted to bookmark. (I'm a reporter who covers this stuff.)🧵1/14
Jack A. Roth, M.D. retweeted
If you read one thing this week, read today's @nytimes piece by @SimarSBajaj bit.ly/49ABdvd It names a truth people with #lungcancer live with every single day.
This well-written article makes it clear that stigma doesn't just hurt people emotionally; it is a life or death barrier. People delay diagnosis, care, and support because they're afraid of being judged.
Lung cancer is not a morality story. And nicotine addiction isn't a bad habit or personal failure - It's a DISEASE and should be treated that way, with compassion and evidence-based care, not judgment.
Thank you, @JimPantelas, for always being so open and honest. And thank you, @drCarterBawam, @hawkeyestudts, @NarjustFlorezMD, and others, for continuing to remind people of the most basic truth: no one 'earns' this disease and no one 'deserves' it!
Please help change the conversation and shift the narrative from shame and blame to hope and humanity.
#KilltheStigma #LCSM #WordsMatter
Jack A. Roth, M.D. retweeted
The most highly cited paper of the year is out!
Cancer Statistics 2026 from @AmericanCancer in @CACancerJournal
acsjournals.onlinelibrary.wi…
"In summary, decades of scientific investment have translated to longer lives for people with even the most fatal cancers" - let's keep going!
China leads research in 90% of crucial technologies - a dramatic shift this century. Nature. 2026 Jan;649(8095):13-14. doi: 10.1038/d41586-025-04048-7. PMID: 41388085.
“At the beginning of this century, the United States led more than 90% of the assessed technologies, whereas China led less than 5%…” US Science must be supported and adequately funded if we are to reverse this alarming trend.
Jack A. Roth, M.D. retweeted
As a liver doctor who has treated patients with hepatitis B for decades, this change to the vaccine schedule is a mistake. The hepatitis B vaccine is safe and effective. The birth dose is a recommendation, NOT a mandate.
Before the birth dose was recommended, 20,000 newborns a year were infected with hepatitis B. Now, it’s fewer than 20. Ending the recommendation for newborns makes it more likely the number of cases will begin to increase again. This makes America sicker.
Acting CDC Director O’Neill should not sign these new recommendations and instead retain the current, evidence-based approach.
Jack A. Roth, M.D. retweeted
Cassidy finally takes at least one glove off. “The ACIP is totally discredited.”
Aaron Siri is a trial attorney who makes his living suing vaccine manufacturers. He is presenting as if an expert on childhood vaccines. The ACIP is totally discredited. They are not protecting children.
cdc.gov/acip/downloads/agend…
Jack A. Roth, M.D. retweeted
Intraop challenges after induction therapy for #NSCLC: Effect of nodal disease on technical complexity. Read the JTCVS Open article by @HopeFeldmanMD, @maraantonoff, et al: doi.org/10.1016/j.xjon.2022.… @rjmehran @BorisSepesi @sgswisher @AraVaporciyan @nicolaszhoudo @JackARothMD #JTCVS
Jack A. Roth, M.D. retweeted
Proud to see @WomenInThoracic in @nytimes. The challenges highlighted are real, yet our meeting was filled with positivity, momentum, and a commitment to a better future for our mentees, patients, and daughters.
Women are wanted and needed in CT surgery!
nytimes.com/2025/11/29/healt…
Congratulations to Dr. Antonoff for her leadership of this groundbreaking organization: Women in Thoracic Surgery. @MDAndersonNews @AATSHQ
nytimes.com/2025/11/29/healt…
Jack A. Roth, M.D. retweeted
A press release summarizes what I thought was the most important lung cancer abstract presented at #ASTRO25. It represents the updated REVISED STARS study results from MDACC. astro.org/news-and-publicati…
Jack A. Roth, M.D. retweeted
Today over 1,000 current and former HHS employees just sent a letter calling on Secretary RFK Jr. to resign.
“Should he decline to resign, we call upon the President and U.S. Congress to appoint a new Secretary of Health and Human Services, one whose qualifications and experience ensure that health policy is informed by independent and unbiased peer-reviewed science.”
"Medical groups must continue to stand up for science and truth." Source: Axios share.google/awnzvDX29OqYMQq…
Chaos reigns
nytimes.com/2025/08/27/healt… via @NYTimes
