
PhD Candidate, U of Denver – Nichols Lab (@SANICHOLS_DU) Animal origins, evolution, sponges, innate immunity, microbes, symbioses. Also dinosaurs. he/him 🏳️🌈
Denver, CO
Joined October 2011
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Came to collect some lake water for a couple experiments this week and accidentally, unapologetically began looking for sponges
#sponge #freshwaterporifera #microbes
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First nuclear tests, then #AgentOrange now the long suffering Johnston Atoll faces #SpaceX and its #military transport plans “If we scare the [birds] off of this island, they don’t have another place to go.” washingtonpost.com/climate-e…
The proteins have learned to crochet
This is apparently a protein-protein interaction diagram... Published in 2024 by Elsevier's Journal of Agriculture and Food Research. doi.org/10.1016/j.jafr.2024.…
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Hello folks!
With exciting new grants and new projects in our lab, ✨we are hiring!✨ Please share with prospective Ph.D. students and/or postdocs interested in evolution, genetics, and microbes!
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Our short report on a remarkable feature of #ctenophores out now: Reverse development in the ctenophore Mnemiopsis. We show that Mnemiopsis is capable of reversal from mature lobate to early cydippid🤩. @MSarsCentre @UiB @biorxivpreprint #rejuvenation
biorxiv.org/content/10.1101/…
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The first week of the 2024 Symbiosis Course @MBLScience is in the books! We studied various cnidarian model organisms to study the molecular and cellular bases of symbiosis. So fun! On to squid, sponges, and amoebas this week! #MBLSYM2024 @MooreFoundation
Well this is fun :)
Looks like there’s a planarian hanging out in this sponge’s osculum
#sponge #biology #invertebrates
Took a Timelapse to commemorate this #sponge being 6 months old!
Alas, an unexpected bout of shrimp cannibalism has stolen the show…
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We have a new pre-print! We characterize the recent, dynamic evolution of caspase-1, caspase-4, and friends 🥰
Evolutionary dynamics of pro-inflammatory caspases in primates and rodents biorxiv.org/cgi/content/shor… #biorxiv_evobio
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Imagine growing a miniature version of the human intestine in the lab to study gut biology in great detail and test medicines before clinical trials? We are happy to share our latest publication on bioengineered human mini-intestines: authors.elsevier.com/sd/arti… Let’s dive in!
Love this shot of a Northern Right Whale Dolphin by @seataceans
These are such beautiful iconic animals, a species of dolphin without a dorsal fin.
They deserve a MUCH better common name.
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My first dissertation chapter is out in mBio! We cultured a vertically transmitted endosymbiont, sequenced its genome, and showed that it is stably inherited across generation when injected into new hosts!
Intracellular endosymbiont is capable of axenic culture and can be stably inherited across host generations. #mBio @gpmaeda @NancyMoran15 journals.asm.org/doi/10.1128…
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When your antibody sucks and what little signal is there is just buried in background
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This is a rare look at a mountain lion on its way to cache (or store) its food. The lion will return to their cache over the next few days to continue eating.
Our Backyard
Glacier View Meadows
Livermore, CO
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E. coli or destined to bring balance to the world? #avatar – at Denver, CO
































