James Joly (@JamesHJoly) profile picture

Part time scientist, full time endurance sport junkie. Interested in all things proteomics, systems biology, and metabolism. Currently @NautilusBio

Joined April 2018
Photo by James Joly (@JamesHJoly)Photo by James Joly (@JamesHJoly)Photo by James Joly (@JamesHJoly)Photo by James Joly (@JamesHJoly)Photo by James Joly (@JamesHJoly)Photo by James Joly (@JamesHJoly)Photo by James Joly (@JamesHJoly)Photo by James Joly (@JamesHJoly)Photo by James Joly (@JamesHJoly)Photo by James Joly (@JamesHJoly)
Explore our new preprint featuring novel data generated on the Nautilus Proteome Analysis Platform! The preprint covers how we use Iterative Mapping to quantify tau proteoforms at the single-molecule level: biorxiv.org/content/10.1101/… #Proteomics #Neuroscience #Proteoforms #AlzheimersDisease
1
2
9
483
Excited to share one of the things we’ve been working on at Nautilus – Iterative Mapping of proteoforms - a first-of-kind single-molecule method to measure proteoforms! We applied this technology to study one of my favorite proteins: Tau. biorxiv.org/content/10.1101/… 1/n🧵
1
2
5
271
And if you'll allow me one very self-indulgent tweet... coming to work these last 6 months and getting to analyze a layer of biological information that nobody has ever really been able to see has been one of the coolest experiences I've ever had.
1
43
And if you're interested in being part of diving into the depths of the proteome... we're hiring! Reach out if you see a fit and are passionate about proteomics. nautilus.bio/careers/
1
54
Single absolute biomarkers aren’t going to cut it.
Why don’t single-protein #biomarkers cut it in biology? In a new episode of "Translating Proteomics," @paragmallick and Andreas Huhmer make the case for new multi-protein, multi-time point, and even multiomic biomarkers that can power #PrecisionMedicine. ow.ly/ZjQg50RAK8N
1
128
In our new #podcast 🎙️and video 📺 series, our Co-Founder and Chief Scientist @paragmallick and Senior Director Andreas Huhmer explore the science of #proteomics, its growing impact on all biological research, and more. Check out the first episode here: nautilus.bio/blog/new-podcas…
3
3
9
1,048