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Jane Dudley

@Jane_Dudley_Lab

Postdoc scientist at the Francis Crick Institute | Excited about the study of ubiquitination at the interface of cell biology and biochemistry

 London, U.K.
crick.ac.uk/research/find-a-researcher/jane-dudley
Joined January 2024
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  • Following69
  • Followers36
8Media
Photo by Jane Dudley (@Jane_Dudley_Lab)Photo by Jane Dudley (@Jane_Dudley_Lab)Photo by Jane Dudley (@Jane_Dudley_Lab)Photo by Jane Dudley (@Jane_Dudley_Lab)Photo by Jane Dudley (@Jane_Dudley_Lab)Photo by Jane Dudley (@Jane_Dudley_Lab)Photo by Jane Dudley (@Jane_Dudley_Lab)Photo by Jane Dudley (@Jane_Dudley_Lab)
Y'all can also find me on Bluesky 💙🦋 bsky.app/profile/janedudley.…
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Super diverse research at @TheCrick annual science meeting! Everything from cancer immunology to pregnancy physiology, viral structural biology, and even ancient genomic history across Europe! Great to see the whole institute get together ☺️
Image from Jane Dudley (@Jane_Dudley_Lab)
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What's a pseudoligase?🧐 Well, it looks a lot like an #ubiquitin E3 ligase but (on its own) can't catalyse ubiquitination. In our new ✨preprint✨ we see 12% of TRIM protein RING domains are actually pseudoligases! Implications in #immunity #cancer #neurodegeneration #TPD +more!
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biorxiv.org/content/10.1101/…
‘Identification of RING E3 pseudoligases in the TRIM protein family’

‘Identification of RING E3 pseudoligases in the TRIM protein family’

TRIpartite Motif (TRIM) family proteins have diverse roles across a broad variety of cellular functions, which are largely presumed to depend on their ubiquitin E3 ligase activity, conferred by a...

biorxiv.org
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@KatrinRittinger @ddeos @katmcphie
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Endlessly fascinating and exciting conference with great discussions #EMBOubiquitin24 ! Can’t wait to get back to the lab with some new ideas…
Image from Jane Dudley (@Jane_Dudley_Lab)
Image from Jane Dudley (@Jane_Dudley_Lab)
Image from Jane Dudley (@Jane_Dudley_Lab)
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Just prepping my data for the #EMBOubiquitin24 meeting at the end of the month! The programme is looking 👌 Hoping Croatia can serve up some sunshine too... meetings.embo.org/event/24-u…
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Gorgeous super-resolution #microscopy to uncover a really interesting mechanism of #mitochondria regulation nature.com/articles/s41586-0…
Lysosomes drive the piecemeal removal of mitochondrial inner membrane

Lysosomes drive the piecemeal removal of mitochondrial inner membrane

Nature - We show that cytosolic inner mitochondrial membrane vesicles, devoid of outer mitochondrial membrane or mitochondrial matrix, are formed during resting state and directly herniate into...

nature.com
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Join us this Saturday 20 July for Discovery Day! 🧪🙌 We’re opening the Crick up to families for a fun-filled day of activities. Will you become an ‘immune cell Avenger?’ 🦸🏽‍♀️ Or does a science magic show sound like your thing? 🪄 🕒 Explore from 11.00am crick.ac.uk/whats-on/discove…
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Really exciting findings from @Dr_James_Lee lab @TheCrick! Whilst working @CrohnsColitisUK I saw how passionate he was about communicating his work to patients & it's amazing to see its impact now whilst working at the Crick 👏🧬 theguardian.com/society/arti… nature.com/articles/s41586-0…
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Had a blast volunteering as a resident scientist for our ‘Sip of Science’ visitor engagement at the #HelloBrain exhibition! @TheCrick 🧠🤓 really recommend a visit - super tactile and fun 💙 N.B. Why do kids always ask the hardest questions?!
Image from Jane Dudley (@Jane_Dudley_Lab)
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🧠🤨😆✨ Super interesting (& witty!) talk ‘Three Lessons About the Brain from the Neuroscience of Emotion’ from scientist, author & communicator @LFeldmanBarrett @TheCrick … followed by a fascinating philosophical panel session! #Neuroscience #Philosophy #BeingHuman #SciComm
Image from Jane Dudley (@Jane_Dudley_Lab)
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Couldn’t help be see parallels between the textural Do Ho Sun ‘Tracing Time’ exhibition @NatGalleriesSco & the fabulous new #HelloBrain @TheCrick ! Both share such beautiful imaginings of our inner worlds! Fascinating! 🧠🧬🩷🩵🎨🧵
Image from Jane Dudley (@Jane_Dudley_Lab)
Image from Jane Dudley (@Jane_Dudley_Lab)
Image from Jane Dudley (@Jane_Dudley_Lab)
Image from Jane Dudley (@Jane_Dudley_Lab)
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It may be raining but I’m still excited for my first ever visit to Germany - guten tag #heidelberg ! 🇩🇪 Looking forward to joining the @EMBO Lab Leadership course tomorrow 👩‍🔬🧑‍🔬
Image from Jane Dudley (@Jane_Dudley_Lab)
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#ValentinesDay... science-style! 👩‍🔬🫶 About 5 yrs ago I was looking at some super-res microscopy & was so excited to find an early endosome (marked by EEA1) in the shape of a heart!💕 Obvs the feeling is mutual @gammoh_lab @EdinUni_IGC embopress.org/doi/full/10.15…
Image from Jane Dudley (@Jane_Dudley_Lab)
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Love this interview with my colleague @katmcphie! So brilliant to hear honest conversations about women in science 👩‍🔬👏 there are still real challenges but also exciting opportunities for amazing careers too. linkedin.com/feed/update/urn… @TheCrick #STEM #WomenInScienceDay
#womeninscience #girlsinstem | The Francis Crick Institute

#womeninscience #girlsinstem | The Francis Crick Institute

We spoke to two Crick researchers who discussed why they love doing science, and how science can be a flexible career for women and parents, but it needs practical changes, role models, and vocal...

linkedin.com
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Brilliant belated lab Christmas party! Building terrarium zen gardens then delicious tapas, drinks & fun with the team. Perfect to pep us up mid-January & motivate our science for 2024 🍾🥼⚡️🪴
Image from Jane Dudley (@Jane_Dudley_Lab)
Image from Jane Dudley (@Jane_Dudley_Lab)
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Debating whether I'm more proud of the pun or the science... Think the latter just about clinches it... #neuroscience #ubiquitin Really loved bringing these studies together to build a cohesive story in my first ever paper as a corresponding author! frontiersin.org/articles/10.…
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