Dad, Fisherman, Collector, Mend-ologist, Microscopist.

Sydenham Ontario, CA
Joined May 2019
Jeff Mewburn retweeted
Multiplexing with primary antibodies from the same species has always been a challenge. The Premix&Stain protocol with Smart Secondary Nanobodies addresses this directly. And here is a 5-color example showing what that looks like in practice. Three targets were labeled using mouse primary antibodies, detected with Smart Secondaries (FluoTag-X2 anti-mouse) plus direct GFP tag labeling for a fourth channel via FluoTag-X2 anti-GFP. Phalloidin STAR BLUE serves as a structural counterstain for actin. ⬜Actin: abberior STAR BLUE Phalloidin 🟥NUP target 1 (GFP-tagged): FluoTag-X2 anti-GFP abberior STAR 550 🟩Golgi: FluoTag-X2 anti-mouse abberior STAR ORANGE 🟦NUP target 2: FluoTag-X2 anti-mouse abberior STAR RED 🟧Mitochondria: FluoTag-X2 anti-mouse abberior STAR deepRED These images showcase two new additions to the nanobody conjugate portfolio, developed in collaboration with NanoTag Biotechnologies: STAR deepRED and STAR 550 conjugates extend the spectral range of the FluoTag toolbox. Find the full portfolio in the comments. #SmartSecondaries #PremixAndStain #STARdyes #FluoTag #abberior #NanoTagBiotechnologies #MulticolorImaging
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Jeff Mewburn retweeted
The ultimate display of a mother's instinct. When a charging hippo threatens her calf, this mother elephant doesn't hesitate to unleash her full power. Raw, unfiltered survival on the African savanna/ - @Crazymoments01
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TIME is pleased to be hosting Dr Paul Kubes as our fall 2025 TIME biannual lecturer @queensutime . Dr Kubes is an expert in microscopy & inflammation who has recently moved to Queen's University. Join us at Medical Grand Rounds @QueensuDOM next Thursday at 0745 & meet Dr Kubes.
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Back in 2017, "Big Sugar" performed at the Danforth Music Hall in Toronto, and #Rush's Alex Lifeson sat in with the band for a couple of songs including the Big Sugar classic "Ride Like Hell" and a cover of Led Zeppelin's "Good Times Bad Times" ...
May 8, 2020 - Big Sugar's "Eternity Now" released, featuring Alex Lifeson on the title track youtube.com/watch?v=kGNxyLnT…
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Neil Peart's drum solo from this show ...
May 8, 2011 - #Rush plays the Malmo Arena in Sweden on the "Time Machine" tour. Here's fan-shot vid of "Workin' Them Angels" from the show
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Congratulations @DavidLillicrap !🎉 Very well-deserved! Proud to be your student.
Congratulations to the #EAHAD Lifetime Achievement Award 2025 winner @DavidLillicrap. #EAHAD2025 #EAHADCongress
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We recently announced a call for applications for 3rd & 4th yr u/grad students to apply for our 2025 summer studentships in cancer research @QueensuSCRI For details, visit our website or send us an email: [email protected] @QueensUHealth @queensuResearch scri.queensu.ca/
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After all these years, I still believe in it:
"It's not a goal that is the goal, it's actually the path towards the goal." 2014 chemistry laureate Stefan Hell shares his best career advice for young scientists and researchers. #NobelPrize
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Little big step towards better live cell imaging.
Bye, bye bleaching – hello #abberior LIVE HaloX! HaloX is an exchangeable label that transiently binds to #HaloTag fusion proteins, allowing long-term protein detection during live-cell imaging. Say goodbye to bleaching issues and capture extended imaging periods with ease! Read more: abberior.rocks/dyes-labels/a… HaloX licensed by @spirochrome #abberior #STED #LiveCellImaging #halo #halotag #confocal #imaging #superresolutionmicroscopy #microscopy #fluorescentmicroscopy #nanoscopy #superresolutionSTEDmicroscopy
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New study from us: science.org/doi/10.1126/scia… High mtDNA copy number promotes lung cancer growth in the mouse, whereas mtDNA depletion in tumor cells reduces tumor growth. This tumor-intrinsic role for mtDNA can be exploited for development of future lung cancer therapies.
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Jeff Mewburn retweeted
Guess what? Mitochondria are weirder than we thought
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One of the best parts of the job, getting to play with the lastest gear!
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Santorini with a few good friends!
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Have seen this logo hundreds of times. Amazing to stand at the doorstep! Oxford has some amazing lattice lightsheet microscopes too!
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I wish the researchers at @harvardmed many fundamental discoveries with the new #Minflux system!
Happening now! @Abberior is installing our new MINFLUX! We are so excited and can’t wait to get this up and running for you all!!! #imaging #scitwitter
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Congratulations Dr. Sue Moffatt 👏
Congratulations to Wilma Hopman & Sue Moffatt, two outstanding members of the #queensuhealth community👏Their extraordinary contributions to the university are being recognized during Homecoming this fall with the #queensu Distinguished Service Award. queensu.ca/gazette/stories/d…
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Our #STED primer is out, you can learn about tips and tricks and current challenges in STED imaging
STED microscopy enhances the spatial resolution by reducing the effective fluorescence emission volume, disrupting the linear relation between excitation and spontaneous emission probability. Find out how in this weeks Primer: go.nature.com/4dD0PYX
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Vanessa Gilles: “We’re not cheaters. We’re damn good players. We’re a damn good team... We proved that today” #CanWNT
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Today would have been Terry Fox’s 66th birthday. Happy birthday, Terry ❤️ A true Canadian hero 🇨🇦🐐
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