
@CUHKMedicine graduate, CardioOncology, echo/HF, epidemiology research. Fellow of @escardio Cellist, classical music lover T/RT = my own.
Hong Kong
Joined August 2014
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Jeffrey Chan, MBChB MPH PhD FESC retweeted
On June 30, 2026, the NEJM retracted the clinical trial that got a drug approved by the FDA, triggering a $3.7B acquisition by Amgen.
The reason: the primary endpoint data was manipulated.
Here's how it happened, how it came to light, and who paid the price. 🧵
Jeffrey Chan, MBChB MPH PhD FESC retweeted
🚨 𝗕𝗥𝗘𝗔𝗞𝗜𝗡𝗚 from #ACC2026: Two major RCTs just challenged everything we thought about Impella pumps in cardiac care.
The results? Surprising.
The implications? Massive.
A thread on what every cardiologist needs to know 🧵👇
Jeffrey Chan, MBChB MPH PhD FESC retweeted
A low-cost and expert-driven medical technology is being used in rural areas in Australia!
The machine is operated by a sonographer remotely (using a gaming controller) and helps perform an ultrasound examination.
Doctor shortages shouldn't mean that patients have to travel more (sometimes for no medical reason), but to use technologies that can extend the reach of medical care.
This is a perfect example of that!
A bit late but excited to have this on #EJPC! We showed that⬆️IL6 was a/w ⬆️eGFR decline, albuminuria, and CKD risk
Thank you to my co-lead @ykjohnson07, amazing guidance from @DrMichaelShapir, & team (tags below)
academic.oup.com/eurjpc/adva…
Jeffrey Chan, MBChB MPH PhD FESC retweeted
You know what’s financially profitable? Treating someone for liver disease throughout their life (Hepatitis B is incurable).
Know what’s not? Giving them a cheap vaccine at birth that prevents it all.
Jeffrey Chan, MBChB MPH PhD FESC retweeted
Contrary to much of the nonsense you may read on here, mRNA vaccines don't cause deaths - they prevent them
This massive study from France showed that not only did mRNA vaccines not increase mortality but they reduced deaths and saved lives
Jeffrey Chan, MBChB MPH PhD FESC retweeted
🚨 NEW: One of the largest COVID-19 vaccine studies ever (28 MILLION people in France) just dropped.
Results?
• 74% lower risk of death from severe COVID-19
• 25% lower risk of all-cause mortality
• No increase in 4-year mortality
• Vaccinated people had lower risk of death from any cause.
In short: mRNA vaccines weren’t just safe — they were protective across the board. 🔥📉
Jeffrey Chan, MBChB MPH PhD FESC retweeted
在宏福苑里的大多数都是经济条件比较一般的香港人,这样的情况应该有好几千个家庭。
真的太让人心酸了,这视频看得我太难过了。
Jeffrey Chan, MBChB MPH PhD FESC retweeted
HK does have a housing issue but the place that is set on fire isn’t “public housing” in the way it’s understood in the West (or even in Hong Kong). I don’t blame the Ms Ren for the error - it’s yet another eg of Western media not appreciating the nuances behind housing in Hong Kong when reporting on the fire.
The place where the fire started is called Wang Fook COURT, which in Hong Kong parlance denotes residential housing construction of which is arranged by the government to be sold below market price to lower middle income earners, but primary buyers who decide to sell at a later date must first pay the difference between purchase price and the place’s market price at time of purchase. In other words, the Government effectively gives interest-free loans to the first hand buyers of such apartments with terms that end when the first hand buyer sells.
By contrast, public housing as the term is typically understood (ie government builds and people rent at lower than market rates) are another category of housing altogether, and in Hong Kong they are typically called “[Name] HOUSE”. While the HK Government has tried emulating Singapore and letting long term tenants buy their own public housing units at below market rates, the take-up hasn’t been great because these apartments are subject to a whole lot more restrictive covenants as to the “enjoyment” (in the property law sense of the term) of them, compared with the COURT apartments that get sold.
Proud to be in the top 2% of #cardiovascular #medicine researchers globally!!! Only possible thanks to @GaryTse1 @vass_vassiliou and Prof CF Ng, and of course @GarimaVSharmaMD @DrMichaelShapir @EChrisDee @Satti_DI and many others!!! elsevier.digitalcommonsdata.…
Honoured that our 2023 publication on #EJPC about the association between psych distress and CV health in #cancersurvivors has been cited by the 2025 @escardio clinical consensus Statement on mental health and CV disease! @Satti_DI @EChrisDee @GarimaVSharmaMD @GaryTse1 @virani_md
Jeffrey Chan, MBChB MPH PhD FESC retweeted
Our 📝 exploring the relationship b/w #SDOH profile & delays in AF ablation is finally out in @JACCJournals #JACCCEP 🔥
Grateful for the mentorship of Dr. David Spragg @HughCalkinsMD @DrJMarine Dr. Ronald Berger @NinoIsakadze @aroniskn
🔗jacc.org/doi/10.1016/j.jacep…
@hopkinsheart
An senior US government official demanding a peer-reviewed journal to retract a study based on Danish data and funded by the Danish government is actually insane. The level of audacity is incomprehensible.
It's ridiculous this was even necessary.
The Annals of Internal Medicine has rejected HHS Secretary RFK Jr's demand to retract the Danish vaccine study of 1.2 million children, finding 'no evidence of scientific misconduct.' (1/2)
reuters.com/business/healthc…"
Jeffrey Chan, MBChB MPH PhD FESC retweeted
It's ridiculous this was even necessary.
The Annals of Internal Medicine has rejected HHS Secretary RFK Jr's demand to retract the Danish vaccine study of 1.2 million children, finding 'no evidence of scientific misconduct.' (1/2)
reuters.com/business/healthc…"
Jeffrey Chan, MBChB MPH PhD FESC retweeted
Published today:
A study of >1.2 million kids doesn’t support aluminum in vax associated with 50 chronic disorders including autism & autoimmune disease.
acpjournals.org/doi/10.7326/…
@NightShiftMD @EpiEllie
Jeffrey Chan, MBChB MPH PhD FESC retweeted
My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15
Jeffrey Chan, MBChB MPH PhD FESC retweeted
Not only was the scientific response to COVID not a failure, it was one of the most astonishing feats of science in human history.
Jeffrey Chan, MBChB MPH PhD FESC retweeted
Super effort by @Satti_DI @JeffreyChansky and @ISHVnews #CardioOb team and collaborators on this important analysis on psychological distress and #CVH in #pregnancy in #JACCadvances @CandiceSilvers1 @Sadeer_AlKindi
Graded association with advserse psychological distress and CVH
Our new study in @JACCJournals #JACCAdvances explores the relationships between psychological distress and #CVH in pregnancy 🤰🫀 #CardioX
Grateful to co-lead this with @JeffreyChansky under the incredible mentorship of @GarimaVSharmaMD
Link: jacc.org/doi/10.1016/j.jacad…
Jeffrey Chan, MBChB MPH PhD FESC retweeted
Our new study in @JACCJournals #JACCAdvances explores the relationships between psychological distress and #CVH in pregnancy 🤰🫀 #CardioX
Grateful to co-lead this with @JeffreyChansky under the incredible mentorship of @GarimaVSharmaMD
Link: jacc.org/doi/10.1016/j.jacad…



























