@JonathanAnomaly

https://xitter.cf/t.co/kd5ubQYRxj

jonathan-anomaly.com/
Joined July 2022
  • Tweets354
  • Following235
  • Followers2.1K
12Media
1/ Today we launch an ambitious paper on the ethics of embryo screening. While the technology is new, our hopes and fears about our future children are as old as the Greek myths, including stories about Hera, goddess of fertility and the namesake of our company @herasight
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Jonathan Anomaly retweeted
Massimo
@Rainmaker1973Oct 20
Maybe one of the most unforgettable surfing moments was captured by David Tereva. [🏄‍♂️ terevadavid]
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“There will be no art, no literature, no science… There will be no distinction between beauty and ugliness. There will be no curiosity, no enjoyment of the process of life. All competing pleasures will be destroyed.” Orwell, 1984
Morgoth
@MorgothsReviewOct 17
This is what the barbarians just burned down in France.
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shoumik
@shmkdbrOct 10
Embryo selection is one of the most interesting technologies out there. If you could choose your kid’s height, would you? What about intelligence? Or more saliently, the risk of key diseases that your kid might be predisposed to? And how do we even know the tech is real? I discuss all this and more with @JonathanAnomaly , whose company @herasight is imputing polygenic risk scores for embryos based on fairly accessible inputs. The quagmire of ethical and scientific questions all this presents, I think, is ultimately tractable and offers reason for optimism
Legible
@LegibleBioOct 10
Embryo selection and the science of creating future people with @JonathanAnomaly from @herasight 00:00 - From Academia to Herasight 07:12 - Is Embryo Selection Controversial 11:31 - Polygenic Scores Explained 21:14 - Why Insurance Hasn’t Covered It 28:18 - Who Uses Screening and Why 32:35 - IVF Limits and Future Tech 36:52 - Selection vs Editing and Gattaca Fears 42:07 - Ethical Boundaries 43:01 - Breakthrough Imputation Proof 48:49 - Winning Clinics Over 51:18 - Ethics Backlash Explained 55:28 - Preference Cascade Theory 59:19 - Blank Slate Debate 01:03:09 - Pleiotropy Tradeoffs 01:08:29 - Autism Risk Predictor 01:13:37 - Repro Tech And Birth Rates 01:20:17 - Relationships And Family Futures 01:24:25 -Books Recs
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Many people out there have grown up thinking they can't have kids as they're so worried about their family risk of conditions like schizophrenia. That changes now. So cool.
Tobias Wolfram
@_twolframOct 8
Today we launch NeuroRisk, the first embryo test for autism and schizophrenia that looks for mutations in evolutionarily important genes. These mutations are individually rare but over 10% of people carry at least one mutation in this class.
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Jonathan Anomaly retweeted
Aella
@Aella_GirlOct 8
I used NeuroRisk for genetic screening for myself, and found that I have a mutation in six3. This likely caused my brother's death shortly after birth, and gives ~25% risk of my own kids suffering the same. I'll be using this info in my embryo selection!
Tobias Wolfram
@_twolframOct 8
Today we launch NeuroRisk, the first embryo test for autism and schizophrenia that looks for mutations in evolutionarily important genes. These mutations are individually rare but over 10% of people carry at least one mutation in this class.
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Alex Strudwick Young
@AlexTISYoungOct 8
An important new innovation from Herasight: NeuroRisk. NeuroRisk identifies embryos carrying damaging mutations in evolutionarily conserved genes, which increase risk for autism, schizophrenia, and other disorders - finding cases missed by polygenic scores and known genes.
Tobias Wolfram
@_twolframOct 8
Today we launch NeuroRisk, the first embryo test for autism and schizophrenia that looks for mutations in evolutionarily important genes. These mutations are individually rare but over 10% of people carry at least one mutation in this class.
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Crémieux
@cremieuxrecueilOct 8
Fascinating! Embryo selection just keeps getting better because the predictors just keep improving all the time. Now, just a handful of mutations = a large IQ and intellectual disability gradient to select on.
Tobias Wolfram
@_twolframOct 8
Today we launch NeuroRisk, the first embryo test for autism and schizophrenia that looks for mutations in evolutionarily important genes. These mutations are individually rare but over 10% of people carry at least one mutation in this class.
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Jonathan Anomaly retweeted
Tobias Wolfram
@_twolframOct 8
Today we launch NeuroRisk, the first embryo test for autism and schizophrenia that looks for mutations in evolutionarily important genes. These mutations are individually rare but over 10% of people carry at least one mutation in this class.
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Announcing a new genetic predictor for autism and other neurodevelopmental disorders:
Tobias Wolfram
@_twolframOct 8
Today we launch NeuroRisk, the first embryo test for autism and schizophrenia that looks for mutations in evolutionarily important genes. These mutations are individually rare but over 10% of people carry at least one mutation in this class.
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