Joshua Iszatt (@JoshuaIszatt) header
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🐙

Perth, Western Australia
Joined January 2022
Photo by Joshua Iszatt (@JoshuaIszatt)Photo by Joshua Iszatt (@JoshuaIszatt)
Watching my first Piers Morgan show (podcast?) with @ericweinstein … I feel most scientists should watch it purely for the chat about peer review 📖 ✅
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Joshua Iszatt retweeted
Speed skater Yang Jingru uses the craziest strategy to to fool everyone and win Gold at the Youth Olympics. teapaw.org/i/status/1818856033948…
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The platypus is possibly the weirdest animals. It’s a mammal but lays eggs, its duck-billed, beaver-tailed, otter-footed and venomous. It has electroreceptors for locating prey, eyes with double cones, no stomach, and 10 chromosomes. It's fluorescent and glows under UV light.
Readers added context they thought people might want to know
The platypus has 10 sex chromosomes¹ ² and a total of 52 chromosomes³ not 10 chromosomes in total. ¹ genomebiology.biomedcentral.com/articles/10.11… ² nature.com/articles/natur… ³ pnas.org/doi/full/10.10…
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Short read phage genome assembly pipeline: github.com/JoshuaIszatt/phan… - A bit more complicated for short reads... are configuration files really the best way?
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Our bacteriophage research to combat global crisis on antimicrobial resistance got funding to train AI models on AWS!
Congrats to @karpievitch and team!. Very proud to get AWS support for this important extension to our Phage program using AI to match phage against AMR bacteria. @telethonkids @WalyanCentre @CurtinUni @CHIRI_curtin @UWAresearch
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Made a simple long read phage assembly pipeline with @AVaitekenas and @samueltmont . - No logging, no checks, nothing fancy, just click and hope (for now)... - Need to turn it into a conda package somehow next? github.com/JoshuaIszatt/phun…
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Joshua Iszatt retweeted
I think this is BIG. MutS protein recognizes mismatches in DNA. AlphaFold3, when given the MutS sequence and long DNA with the mismatch, finds the mismatch and models the complex in the correct conformation.
Replying to @rfleiro
You won't believe... Left - crystal structure of MutS bound to G:T mismatch, in red (PDB ID: 1E3M). Right - AlphaFold3 model with longer and different DNA and A:C mismatch, in red... It managed to find the mismatch?? 🤯The models are here: oc.embl.de/index.php/s/eJwzE…
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Whilst this is an issue… it is also hilarious 😂
Somehow my reviewers always needed 3 months of convincing about the choice of Kruskal–Wallis versus Wilcoxon Rank-Sum as the test of statistical significance for supplementary figure 7j but giant AI generated rat balls just sails right though sure why not
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Joshua Iszatt retweeted
🤪🤪🤪🤪🤪🤭
Replying to @BBCRadio1PR
Congratulations to Jess Iszatt who will become the new host of BBC Introducing on Radio 1 (Sundays, 11pm – 12am) 💥 Her first show will be on Sunday 10 September. Welcome to the Radio 1 family @jjiszatt 💫 2/4
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I have many friends who refuse vaccination for hilarious reasons but rabies is not the way to prove it 😂 - “He’s out of line… but he’s right”
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Shameless tweet naming someone a “Karen” for caring about the environment… 🤦🏻‍♂️
Karen loses her mind over a man sitting in his Tesla, claims it puts out toxic emissions that are endangering the lives of nearby residents.
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If I got paid £50 per review I would do one once a week.
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🦠🧬🖥️ Excited to announce Bakta v1.7.0 AND a major DB update! New Features: - A lightweight DB version -> only 1.2 Gb (zipped) - Gene symbol curation for CDS & operons - A metagenome mode github.com/oschwengers/bakta… More information below 👇 (1/10)
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Thankyou @ConquerCF for your support of this important #phagetherapy research, as covered on @9NewsPerth by @_KelHaywood. Find out more about phage therapy as a treatment option for #antibioticresistant #superbugs 👉bit.ly/3DPP69Q @telethonkids @PCHFWA @PerthChildrens
Perth scientists are tackling superbugs that are resistant to antibiotics. For those with serious diseases like cystic fibrosis, their work is instrumental to keeping them healthy. @_KelHaywood #9News
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Joshua Iszatt retweeted
Absolutely gutted by Last of Us portrayal of lodgepole pine 16 km west of Boston. But hey, novel mycorrhizae and climate conditions may present new opportunities for rapid range shifts. #lastofusepisode3
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Joshua Iszatt retweeted
Extremely grateful and humbled to receive the Best Oral Presentation Award from @ASMicrobiology at the @ischemo 32nd ICC! Thank you @micro_rp for the insightful talk and advices given at the conference :)
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Replying to @JoshuaIszatt
@JoshuaIszatt from @WalyanCentre is presenting at International Congress of Antimicrobial Chemotherapy today. “We describe the characterisation of lytic bacteriophages active against MRSA, which is an antibiotic resistant type of bacteria.” (1 of 2) @ischemo
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