@KlcoLab

The Klco lab at @stjuderesearch - Defining the molecular and biological causes of pediatric myeloid tumors

 Memphis, Tennessee
stjuderesearch.org/site/lab/klco
Joined May 2021
  • Tweets65
  • Following233
  • Followers264
21Media
Our POE summer student, Elizabeth, gave an outstanding presentation on our ongoing research into UBTF tandem duplications. It's been another fantastic summer in the lab, and we are grateful for your incredible effort. Wishing you all the best! 👏👏👏 @StJude @StJudeResearch
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Had a blast at the annual Klco Lab Pool Party yesterday! Fun in the sun and great food. 🌞🍔 #SummerVibes #LabLife
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🎉 Big congratulations to our very own Jeff Klco on his promotion to Full Member @StJude ! Congrats, Jeff – you deserve it! 👏 @StJudeResearch
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🎉 Klco Lab’s first graduate student Lauren Ezzell has successfully completed their candidacy exam! 🥳 Huge congratulations on this amazing achievement! Here's to more groundbreaking research and success ahead. 🌟 #AcademicAchievement #GradStudentLife
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Had a great time at the @KlcoLab social! Work hard, play hard! 😤 @wiseacrebrew
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Molecular ‘super-glue’ shows promise of cancer drug discovery platform stjude.org/media-resources/n…

Molecular ‘super-glue’ shows promise of cancer drug discovery platform

Learn how St. Jude created a molecular super-glue to target cancer-related protein casein kinase 1 alpha (CK1α) & how the platform may lead to new treatments.

stjude.org
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Updated genomic landscape for pediatric acute myeloid leukemia enables new treatment possibilities: stjude.org/media-resources/n…

Updated genomic landscape for pediatric acute myeloid leukemia enables new treatment possibilities

Scientists at St. Jude Children’s Research Hospital refined and enhanced the classification system for a type of pediatric leukemia using genomic and transcriptomic analysis.

stjude.org
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The Klco lab dinner was the perfect way to catch up and compare notes after a long day of learning from the best and brightest minds that #ASH23 has to offer!
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The Klco lab is proud to have Masayuki Umeda presenting his recent data on the characterization of NUP98-rearranged leukemias. #ASH23
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Congratulations Jeff for being selected as the mentor of the year at @StJudeResearch well deserved!
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Klco lab at #ASH22. It was such a great meeting. Looking forward to seeing everyone next year.
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The Klco Lab retweeted
Andy Lane@lane_andy13 Dec 2022
Great dinner with current and former trainees of my mentor Tim Ley, who will receive the Stratton Medal tomorrow from @ASH_hematology #ASH2022. This field is all about mentor/mentee relationships and the communities they build.
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We got the cover!
Journal of Clinical Investigation
@jclinicalinvest1 Nov 2022
#Cover: Samd9l mutant mice recapitulate phenotypes seen in pediatric myelodysplastic syndromes: buff.ly/3zoHdGm Image: non-random chromosomal deletions of the mutant Samd9l locus in the mouse model; Credit: Virginia Valentine & Marcus Valentine @KlcoLab @StJudeResearch
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Relapse is common in children with acute myeloid leukemia and can be complicated to treat. Researchers at St. Jude found a mutation in AML that can be used to stratify high-risk patients and better guide treatment. bit.ly/3T05ARV @OncologyTimes @BCD_AACR @KlcoLab
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Check out our recent collaborative work co-led by Masayuki Umeda. We identified a new AML subtype with CBFB alteration. @BloodJournal @StJudeResearch
Munich Leukemia Laboratory@leukaemielabor4 Oct 2022
Reanalysis of 553 pediatric #AML #WTS led to the identification of a new AML subtype with recurrent 9bp insertions in exon 3 of CBFB. The GEP of cases with CBFBins was similar to CBFB::MYH11 AML but had a more stem-like signature (BCL2L14, MEIS1, HOXA). doi.org/10.1182/blood.202201…

Description of a novel subtype of acute myeloid leukemia defined by recurrent CBFB insertions

TO THE EDITOR:

ashpublications.org
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Check out this article on our recent exciting #SAMD9L story led by @SherifAbdlhamed and @MelvinThomasIII! @jclinicalinvest @StJudeResearch jci.org/articles/view/158869 blogs.stjude.org/progress/ne…
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@Hema_News @HSC_papers #BMF #Hematology
Congratulations @juanmar_barajas !
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In honor of postdoc appreciation week, we would like to recognize the wonderful postdocs in the lab! Thank you for all that you do!
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Also, @juanmar_barajas celebrated his way and gave a nice talk about his project for the experimental hematology seminar, good job Juan!
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